Wenpeng Dai

Research Field

Trifluoromethylation

10.1016/j.tet.2015.08.016

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Citations (20)

NNICE 2024 TOC

Wei Xie Xueying Zhang Xiaole Huang Fengbo Zheng Lifen Jiang

10.1109/nnice61279.2024.10498382

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ChemInform Abstract: Silver‐Mediated anti‐Markovnikov and Markovnikov‐Selective Hydrotrifluoromethylthiolation of Terminal Alkynes.

ChemInform (2016)

Wei Wu Wenpeng Dai Xinfei Ji Song Cao

Abstract The direct oxidative hydrotrifluoromethylthiolation of terminal alkynes yields vinyl trifluoromethyl thioethers as anti‐Markovnikov and Markovnikov adducts in moderate to good yields depending on the reaction conditions.

Markovnikov's rule

10.1002/chin.201645067

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ChemInform Abstract: Palladium‐ and Nickel‐Catalyzed Kumada Cross‐Coupling Reactions of gem‐Difluoroalkenes and Monofluoroalkenes with Grignard Reagents.

ChemInform (2015)

Wenpeng Dai Juan Xiao Guanyi Jin Jingjing Wu Song Cao

10.1002/chin.201515082

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CCDC 1405947: Experimental Crystal Structure Determination

The Cambridge Structural Database (2015)

Guanyi Jin Xuxue Zhang Dan Fu Wenpeng Dai Song Cao

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc1j604w

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ChemInform Abstract: Mild and Metal-Free Trifluoromethylation and Pentafluoroethylation of gem-Difluoroalkenes with TMSCF₃and TMSCF₂CF₃.

ChemInform (2015)

Guanyi Jin Xuxue Zhang Dan Fu Wenpeng Dai Song Cao

A direct and efficient approach for the trifluoromethylation and pentafluoroethylation of 1,1-diaryl-2,2-difluoroethenes with TMSCF3 and TMSCF2CF3 in the presence of TBAF is developed.

Trifluoromethylation

10.1002/chin.201602050

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Copper- and Nickel-Catalyzed Cross-Coupling Reaction of Monofluoroalkenes with Tertiary, Secondary, and Primary Alkyl and Aryl Grignard Reagents

Organometallics (2018)

Hongyan Shi Wenpeng Dai Biyun Wang Song Cao

A highly efficient cross-coupling reaction of monofluoroalkenes with tertiary, secondary, and primary alkyl and aryl Grignard reagents in the presence of a catalytic amount of copper or nickel catalyst, respectively, has been developed. The reactions proceeded smoothly at room temperature, providing (E)-alkene isomers in moderate to high yields. Plausible mechanisms of the Ni-catalyzed coupling reaction of monofluoroalkene with Grignard reagents are suggested.

Alkene

Coupling reaction

Grignard reagent

10.1021/acs.organomet.7b00859

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Citations (36)

Synthesis of Exocyclic Trisubstituted Alkenes via Nickel‐ Catalyzed Kumada‐Type Cross‐Coupling Reaction of gem‐ Difluoroalkenes with Di‐Grignard Reagents

Advanced Synthesis & Catalysis (2016)

Wenpeng Dai Xuxue Zhang Juan Zhang Yingyin Lin Song Cao

Abstract A practical, nickel‐catalyzed Kumada‐type double cross‐coupling reaction of gem ‐difluoroalkenes with 1,4‐ or 1,5‐di‐Grignard reagents was developed. The reaction proceeded efficiently at room temperature and a variety of cyclization products, arylmethylenecyclopentanes and arylmethylenecyclohexanes, were obtained in high to excellent yields, respectively. magnified image

Coupling reaction

Grignard reagent

10.1002/adsc.201500889

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Citations (31)

ChemInform Abstract: Copper‐Catalyzed Coupling Cyclization of gem‐Difluoroalkenes with Activated Methylene Carbonyl Compounds: Facile Domino Access to Polysubstituted Furans.

ChemInform (2015)

Xuxue Zhang Wenpeng Dai Wei Wu Song Cao

Abstract The first general route for the efficient synthesis of trisubstituted furan derivatives is developed.

Domino

Methylene

10.1002/chin.201541122