S.C. Ng

Chinese University of Hong Kong

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M. H. Kuok

National University of Singapore

Y. Li

Chinese Academy of Sciences

Z.P. Lu

Shanghai Institute of Optics and Fine Mechanics

Y. Li

Taiyuan University of Science and Technology

Yuan Ping Feng

North University of China

C. K. Ong

National University of Singapore

P.G. Adaikan

National University of Singapore

H. S. Lim

Sungkyunkwan University

H. Jones

Barnsley Hospital

Xiao Hu

Shanxi Medical University

Cooperative Institutions

National University of Singapore

National University Hospital

National University Health System

University College London

Nanyang Technological University

KK Women's and Children's Hospital

Tan Tock Seng Hospital

University of Calgary

Agency for Science, Technology and Research

Chinese Academy of Sciences

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Glass formation in La-based La55Al25(NiCu)20 alloys by Bridgman solidification

Journal of Non-Crystalline Solids (1999)

Z.P. Lu Y. Li S.C. Ng Yuan Ping Feng

Growth velocity

Temperature Gradient

10.1016/s0022-3093(99)00140-4

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Citations (3)

A retrospective record review of tuberculous infections in rheumatoid arthritis patients on biologics in Malaysia.

PubMed (2023)

A M N Nor Hashimah Adrian Lim M. Mohd Zain Seda Gün Liza Mohd Isa

The aim of this study was to analyse the clinical characteristics of patients with rheumatoid arthritis receiving biologics therapy and investigate the association between types of biologics and tuberculosis (TB) infections in 13 tertiary hospitals in Malaysia.

Tocilizumab

Abatacept

Prednisolone

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Citations (0)

Establishing Enteral Feeding in Preterm Infants with Feeding Intolerance: A Randomized Controlled Study of Low-dose Erythromycin

Journal of Pediatric Gastroenterology and Nutrition (2003)

S.C. Ng Joseph Manuel Gomez Victor Samuel Rajadurai Seang‐Mei Saw Seng‐Hock Quak

A prospective, double-blind, randomized, controlled trial was conducted to evaluate the effect of low-dose erythromycin on the time taken to attain full enteral feedings in preterm infants with very low birth weight and feeding intolerance.Two groups of preterm infants (birth weight

Enteral administration

10.1097/00005176-200311000-00009

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Citations (55)

Cholinergic and adrenergic receptors in the oesophageal, pyloric, and special sphincters of the puffer fish, Tetraodon immaculatus

Comparative and General Pharmacology (1973)

S.C. Ng Y. F. Teh Chong Kiat Tan

10.1016/0010-4035(73)90019-0

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Citations (2)

P270 A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease

Journal of Crohn s and Colitis (2023)

Dominik Bettenworth Mark E. Baker W Bemelmann David H. Bruining Geert R. D’Haens

Abstract Background Small bowel fibrostenotic strictures are common in patients with Crohn’s disease (CD). No global consensus recommendations on definitions, diagnosis and clinical management are available. Methods Several systematic reviews followed by a RAND/University of California Los Angeles appropriateness study on the definitions, diagnosis and clinical management of fibrostenosing CD in clinical practice were performed. A panel of 28 global experts and a patient representative were convened. They assessed a total of 152 candidate items. The items were subsequently evaluated for appropriateness. Results No accurate predictive biomarkers are available for naïve or anastomotic fibrostenosing strictures. Accurate diagnosis of fibrostenosing CD requires cross-sectional imaging which should evaluate bowel wall thickness, luminal narrowing and prestenotic dilatation. A potential inflammatory component should be assessed. Abdominal cross-sectional imaging was considered necessary prior to any treatment decision. The panel proposed an approach to medical, endoscopic, and surgical therapies (Figure 1 and Table 1). Technical characteristics for endoscopic balloon dilation and follow up strategies after successful dilation therapy were identified. Appropriateness, types and performance of different surgical approaches in various settings were evaluated. Conclusion This global consensus provides clinical guidance for the diagnostic and therapeutic management of patients with fibrostenotic CD.

Balloon dilation

Clinical Practice

10.1093/ecco-jcc/jjac190.0400

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Citations (1)

O0065 ESTABLISHING REFERENCE VALUES FOR BONE MINERAL DENSITY AND BODY COMPOSITION OF PRETERM NEONATES LESS THAN 2500 G USING DUAL-ENERGY X-RAY ABSORPTIOMETRY

Journal of Pediatric Gastroenterology and Nutrition (2004)

S.C. Ng Yung Seng Lee Siew Leng Low PL Ooi

Introduction: Preterm neonates are susceptible to metabolic bone disease (hypophosphataemic rickets of prematurity) and compromised nutritional status because of “lost opportunities” from an earlier “exutero” existence and subsequent low calcium and phosphorus intake. We evaluated bone mineral density and body composition using dual-energy X-ray absorptiometry (DXA) within the first 2 weeks of life with the view to establishing norms to correlate with serum biochemical indexes. Methods: Dual-energy X-ray absorptiometry (DXA) (XR-36; Norland Corporation, Fort Atkinson, WI; small subjects mode) was used to measure bone mineral density and body composition of 15 well preterm neonates. Preterm neonates with birth weight <2500 grams and without multiple congenital anomalies were recruited once they were off oxygen and ventilator support. The neonates were clothed in standard hospital-issued vests and plastic commercial diapers and were sedated for the procedure. Results: The mean gestation and weight at birth were 32.6 ± 2.1 weeks and 1646 ± 455 g respectively. DXA measurements were made at the mean gestation of 35.1 ± 1.4 weeks and median postnatal age of 16 ± 2.2 days. All the neonates were on a median of 152 ± 7 ml/kg/day feeds (117 ± 6 kcal/kg/day) and had been on feeds for a median of 14 ± 2.4 days. 8 infants were on premature formula alone, 3 on fully-fortified expressed breast milk (FFEBM) alone, 3 on a combination of FFEBM and premature formula and the last infant on a combination of FFEBM and Neosure. The median total body bone mineral density was 0.19 ± 0.05 g/cm2, bone mineral content 36 ± 12.2 g, lean mass 1631 ± 386 g and fat mass 195 ± 113 g. The mean serum biochemical indexes were calcium 2.49 ± 0.08 mM, phosphate 2.2 ± 0.31 mM and alkaline phosphatase 245 ± 83 U/L. None of these neonates required phosphate or vitamin D supplementation. Conclusion: We hope that these reference values/norms will aid the clinician in preventing or treating rickets of prematurity early. Early intervention may be indicated if sequential DXA scans show a significant drift away from these norms.

Dual-Energy X-ray Absorptiometry

Bone mineral content

Metabolic bone disease

10.1097/00005176-200406001-00067

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Therapeutic and reproductive cloning--implications and recommendations.

PubMed (2003)

S.C. Ng Yoke Lan Ng Swee‐Lian Liow N Chen

The announcement of Dolly's birth took the world by storm, mainly because what was thought impossible has become possible. Optimism that new approaches in agriculture and medicine abound, as much as fear and imagination leading to Frankenstein-like scenarios. Scientifically, cloning refers to replicating an animal with the same nuclear genetic material; whilst it may refer to embryos as the source material, the current storm refers to differentiated ("somatic") cells. Cloning technology is useful in the following areas: agriculture, to produce animals of superior or specific qualities; endangered animals, to increase genetic diversity through widening the gene pool; understanding fundamental questions in developmental embryology, through the use of laboratory animals; and in human therapy, to produce cells and possibly tissues for repair and regeneration. In the first 2 instances, it is reproductive cloning. In the last instance, it is therapeutic cloning, as no individuals are "produced". Human reproductive cloning is not allowed by all governments that have deliberated on it, and therapeutic cloning is allowed by some under certain circumstances. As therapeutic cloning has great potential in cures of many diseases, it should be allowed but with safeguards to prevent abuse and reproductive cloning in the human.

Cloning (programming)

Human cloning

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A simple method to determine segregation coefficients for impurities in pulsed-laser annealed silicon

Physics Letters A (1983)

H. Tan C. K. Ong S.C. Ng

Bismuth

Pulsed laser

10.1016/0375-9601(83)90374-2

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Citations (1)

Brillouin spectroscopic evidence for a relaxation mode in ferroelectricPbHPO4andPbDPO4

Physical review. B, Condensed matter (1995)

M. H. Kuok S.C. Ng D. J. Lockwood

Brillouin spectra of ferroelectric ${\mathrm{PbHPO}}_{4}$ (${\mathit{T}}_{\mathit{c}}$=310 K) and its deuterated isomorph ${\mathrm{PbDPO}}_{4}$ (${\mathit{T}}_{\mathit{c}}$=462 K) have been measured as a function of temperature across their transition temperatures. Certain longitudinal acoustic waves are found to exhibit anomalous propagation in the vicinity of ${\mathit{T}}_{\mathit{c}}$. The relaxation times, ${\mathrm{\ensuremath{\tau}}}_{0}$, for a noninteracting dipole are evaluated from the Brillouin shifts, based on a phenomenological approach. The ${\mathrm{\ensuremath{\tau}}}_{0}$ values are the same in both ${\mathrm{PbHPO}}_{4}$ and ${\mathrm{PbDPO}}_{4}$, indicating that the ferroelectric transition is driven by an order-disorder relaxation mode. This study also reveals that the paraelectric phase symmetry is, on a macroscopic scale, centrosymmetric.

Brillouin zone

10.1103/physrevb.51.8005

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Citations (4)

Critical cooling rates of glass formation in Mg-based Mg-Ni-Nd alloys

Journal of Materials Science Letters (1995)

Y. Li S.C. Ng C. K. Ong Huey Hoon Hng H. Jones

10.1007/bf00274627

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Citations (10)