Robert‐Paul Juster

Université de Montréal

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Sonia Lupien

Université de Montréal

Marie‐France Marin

Institut Universitaire en Santé Mentale de Québec

Shireen Sindi

Karolinska Institutet

Jens C. Pruessner

University of Konstanz

Philippe Kerr

Université de Montréal

Martin Picard

Columbia University

L. Zachary DuBois

University of Oregon

Charles‐Édouard Giguère

Institut Universitaire en Santé Mentale de Québec

Catherine Raymond

Institut Universitaire en Santé Mentale de Québec

Bruce S. McEwen

Rockefeller University

Cooperative Institutions

Université de Montréal

138

Hôpital Louis-H Lafontaine

Douglas Mental Health University Institute

Institut Universitaire en Santé Mentale de Québec

McGill University

Columbia University Irving Medical Center

University of Toronto

Columbia University

Université du Québec à Montréal

Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal

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Impact of Stress and Strain on Current LGBT Health Disparities

Springer eBooks (2017)

Robert‐Paul Juster Jennifer A. Vencill Philip J. Johnson

Stressor

Allostatic load

Minority Stress

Stigma

10.1007/978-3-319-54509-7_4

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Citations (31)

Diurnal and stress reactive cortisol profiles are altered when adjusting for sex hormones

Psychoneuroendocrinology (2015)

Robert‐Paul Juster Jens C. Pruessner Sonia Lupien

10.1016/j.psyneuen.2015.07.580

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Citations (2)

Should we suppress or reappraise our stress?: the moderating role of reappraisal on cortisol reactivity and recovery in healthy adults

Anxiety Stress & Coping (2019)

Catherine Raymond Marie‐France Marin Robert‐Paul Juster Sonia Lupien

ABSTRACTBackground: People differ in their ability to regulate their physiological stress response. Individual differences in emotion regulation strategies such as suppression and reappraisal may explain this differential response to stress.Objective: The aim of the current study was to assess whether daily use of suppression and reappraisal as well as their interaction predicted physiological stress reactivity and/or recovery, as assessed by variations in cortisol levels.Method: Thirty-eight healthy young adults (13 men) completed the Emotion Regulation Questionnaire and were exposed to a psychosocial stressor, throughout which salivary cortisol was measured.Results: Linear regressions showed main effects of reappraisal and suppression on cortisol reactivity and a main effect of suppression on cortisol recovery, where both strategies were positively associated with stress phases. Moreover, results showed a significant interaction of suppression by reappraisal in predicting both cortisol reactivity and recovery. Simple slope tests revealed that reappraisal moderated the association between suppression and both phases of cortisol responsivity.Conclusion: Our results suggest that reappraisal represents a protective factor against the deleterious effects of suppression on stress responsivity. This study underlines the importance of investigating emotion regulation strategies as a means to understand individual differences in vulnerability to stress-related psychopathologies such as anxiety and depression.

Reactivity

Stressor

10.1080/10615806.2019.1596676

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Citations (23)

Why Does Allostatic Load Not Differ Among Women of Diverse Sexual Orientations?

Journal of Women s Health (2021)

Gabriel Desjardins Mathias Rossi Robert‐Paul Juster

Allostatic load

10.1089/jwh.2021.0347

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Citations (4)

Cortisol reactivity correlates with subjective stress in women in their luteal phase but not in women using oral contraceptives or men

Psychoneuroendocrinology (2017)

Catherine Raymond Marie‐France Marin Robert‐Paul Juster Sonia Lupien

10.1016/j.psyneuen.2017.07.326

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Citations (2)

Increased frequency of mind wandering in healthy women using oral contraceptives

Psychoneuroendocrinology (2018)

Catherine Raymond Marie‐France Marin Robert‐Paul Juster Sarah Leclaire Olivier Bourdon

Mind Wandering

Vulnerability

Depression

Cognitive vulnerability

10.1016/j.psyneuen.2018.11.005

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Citations (12)

A step-by-step and data-driven guide to index gender in psychiatry

PLoS ONE (2024)

Enzo Cipriani Eugénie Samson-Daoust Charles‐Édouard Giguère Philippe Kerr Cécile Le Page

Beyond sex as a binary or biological variable, within-sex variations related to sociocultural gender variables are of increasing interest in psychiatric research to better understand individual differences. Using a data-driven approach, we developed a composite gender score based on sociodemographic and psychosocial variables showing sex differences in a sample of psychiatric emergency patients upon admission (N = 1708; 39.4% birth-assigned females; mean age = 40 years; age standard deviation = 14). This gender score was extracted from a confirmatory factor analysis (CFI = 0.966; RMSEA = 0.044, SRMR = 0.030) and could predict a person’s birth-assigned sex with 67% accuracy. This score allowed the further identification of differences on impulsivity measures that were absent when looking solely at birth-assigned sex. Female birth-assigned sex was also associated with higher rates of mood and personality disorder diagnoses, while higher feminine gender scores were related to higher proportions of anxiety and mood disorder diagnoses. By contrast, male birth-assigned sex and higher masculine gender scores were associated with higher proportions of psychotic and substance use disorder diagnoses. Patients with undifferentiated gender scores (i.e., scoring between masculine and feminine threshold defined by terciles) were more represented in the psychotic disorder group. Considering both sex and gender in psychiatric research is essential and can be achieved even when using secondary data to index gender comprised of demographic and psychosocial variables.

10.1371/journal.pone.0296880

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Citations (5)

Elevated allostatic load is associated with poorer response to repetitive transcranial magnetic stimulation in treatment-resistant depression

Psychiatry Research (2024)

Christophe Longpré-Poirier Jean‐Philippe Miron Nicolas Garel Eugénie Samson-Daoust Élie Rizkallah

Allostatic load

Depression

10.1016/j.psychres.2024.116122

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Citations (0)

Does Time Perspective Modulate Perceived Stress and Reactive Cortisol Levels in Healthy Adults?

PsycEXTRA Dataset (2013)

Lening A. Olivera-Figueroa Marie France Marin Julie Katia Major Robert‐Paul Juster Sonia Lupien

10.1037/e616452013-001

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Mitochondrial and Stress-Related Psychobiological Regulation of FGF21 in Humans

medRxiv (Cold Spring Harbor Laboratory) (2025)

Mangesh Kurade Natalia Bobba-Alves Catherine Kelly Alexander Behnke Quinn Conklin

Abstract FGF21 is a metabolic hormone induced by fasting, metabolic stress, and mitochondrial oxidative phosphorylation (OxPhos) defects that cause mitochondrial diseases (MitoD). Here we report that acute psychosocial stress alone (without physical exertion) decreases serum FGF21 by an average of 20% ( p <0.0001) in healthy controls but increases FGF21 by 32% ( p <0.0001) in people with MitoD—pointing to a functional interaction between the stress response and OxPhos capacity in regulating FGF21. We further define co-activation patterns between FGF21 and stress-related neuroendocrine hormones and report novel associations between FGF21 and psychosocial factors related to stress and wellbeing, highlighting a potential role for FGF21 in meeting the energetic needs of acute and chronic psychosocial stress.

FGF21

10.1101/2025.01.30.25321437

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