Sue Sherwin

Birmingham City Hospital

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Milk 99Tcm-HIDA test for enterogastric ble reflux

British journal of surgery (1982)

M Sorgi L. K. Harding D.A. Causer Sue Sherwin I A Donovan

10.1002/bjs.1800690824

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The pharmacokinetics of 99mTc HIDA in man and its relationship to intra-gastric bile acids.

PubMed (1984)

Harding Lk M Sorgi Wolverson Rl F Mosimann Sue Sherwin

We have examined the pharmacokinetics of 99mTc diethyl HIDA in five patients with a T-tube inserted into their common bile duct after choledocotomy. Blood clearance was rapid with 27.5% of the injected dose in the circulation at 2.5 min and 5% at 30 min. The peak bile excretion of 15.4% occurred between 45 and 60 min after injection of the HIDA. By 2 h 69% of the dose was excreted in the bile and 14% in the urine. In a second group of 33 patients a naso-gastric tube was passed after injection of HIDA. The patients drank 400 ml of 10% dextrose and aliquots of the stomach contents were aspirated every 10 min for an hour. In specimens with a pH greater than 4, the amount of HIDA correlated well (p less than 0.01) with the amount of bile acid determined by an enzymatic method.

Stomach tube

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