RESUME La tuberculose du Cavum est peu frequente et son association a une localisation tuberculeuse nasosinusienne est rare. Elle est caracterisee par une presentation clinique qui fait tout de suite penser a une pathologie tumorale maligne. Le diagnostic repose sur l'examen anatomopathologique. Le traitement est essentiellement medical a base d’anti bacillaire. ABSTRACT Cavum tuberculosis is uncommon and its association with nasosinus tuberculosis localization is rare. It is characterized by a clinical presentation which immediately brings to mind a malignant tumor pathology. The diagnosis is based on anatomopathological examination. The treatment is mainly medical based on anti-bacillary.
Introduction: Intraductal carcinoma is often associated with high-grade, high-stage adenocarcinoma. Its frequency is variable and it is considered a poor prognostic factor. In our context, when prostatic carcinoma is diagnosed, pathologists do not always report the presence of this anatomopathological entity. We therefore conducted a study to determine the epidemiological and anatomopathological profile of patients with this lesion in Dakar. Materials and Methods: This is a retrospective descriptive study covering a 1-year period from January to December 2022. It focused on cases of intraductal carcinoma diagnosed among prostatic carcinomas collected in the anatomopathology laboratories of Hôpital Général Idrissa Pouye (HOGIP) and Hôpital Militaire de Ouakam (HMO). It was based on archives of anatomopathological reports, blocks and slides. A total of 200 cases of prostatic carcinoma were collated and reviewed to identify those presenting with intraductal carcinoma according to the diagnostic criteria of Guo and Epstein. Results: 87 cases of intraductal carcinoma were found, representing 43.5% of prostatic carcinomas. The mean age was 71 years. Patients in their seventh decade were the most represented, i.e. 42.5%. The majority of samples examined were biopsies (72.4%). The mean PSA level was 965.91 ng/ml, with extremes ranging from 0.03 to 10,000 ng/ml. Histologically, 96.5% of cases (N = 84) were invasive prostatic carcinoma. Gleason score 8 (4 + 4) was the most common, accounting for 42.53% (N = 37). On average, the study found four (04) foci of intraductal carcinoma per specimen, with extremes ranging from 1 to 30. Dense cribriform architecture accounted for 78.16%, loose cribriform for 11.5%, solid for 8.04% and micropapillary for 2.3%. Six cases (6.9%) showed foci of comedonecrosis. The vast majority of radical prostatectomies (87.5%) were classified as pT3. Node invasion and perineural sheathing were observed in 12.5% and 52.32% of cases respectively. Conclusion: Intraductal carcinoma is a poor prognostic factor that must be systematically reported in the anatomopathological report. In Senegal, it is often associated with advanced stage, high-grade carcinoma and high PSA levels.
La localisation cervicale de la tuberculose est rare et peut prendre l'apparence d'un cancer du col utérin. La présentation pauci-symptomatique et l'évolution insidieuse sont à l'origine d'un retard diagnostique. Les symptômes communément rencontrés sont non spécifiques, ce qui contribue au retard thérapeutique et majore le risque d'infertilité qui reste la séquelle quasi inéluctable. Nous rapportons un cas de tuberculose du col utérin dont le diagnostic de prime abord n'a pas été évident. En effet une patiente a été adressée à notre département pour suspicion de cancer du col utérin. Le diagnostic de suspicion de cancer a été alors retenu devant un col qui saignait au contact avec une tomodensitométrie abdomino-pelvienne en faveur d'une tumeur du col utérin. Une biopsie de confirmation histologique a été indiquée. On a retrouvé à l'examen anatomopathologique, un granulome épithélio-giganto-cellulaire avec nécrose caséeuse, compatible avec une tuberculose cervicale. La recherche d'un terrain était négative. Un traitement antituberculeux instauré a conduit à la guérison. Retenue souvent sur la base d'éléments présomptifs, la décision diagnostique et thérapeutique de tuberculose du col cervicale reconnait la place de l'examen anatomopathologique.
Ewing’s sarcomas are a heterogeneous group of aggressive tumors affecting mostly children and young adults. They account for 10% of primary malignancies of the bones and 3% of all malignancies in children. They mainly affect the long bones, pelvis, and ribs. Cranial vault localization is extremely rare and indeed account for less than 1% of all localizations in the body. We are reporting the unusual case of a 3-year-old child who presented to our unit with a macrocrania which had been evolving for 2 months prior to his admission, associated with sporadic vomiting and a right frontal swelling that was gradually installed. The cerebral computed tomography scan showed a right frontoparietal lytic tissular process, heterogeneously enhanced after injection of contrast material; with dural invasion and intraparenchymal extension. The child was biopsied and the pathological examination concluded Ewing’s sarcoma. The evolution was fatal with the passing of the child 2 weeks after the biopsy.
RESUME Introduction. Le cancer broncho-pulmonaire primitif est un probleme de sante publique peu etudie au plan anatomopathologique au Senegal. Le but de notre travail etait de decrire le profil epidemiologique et histologique de ce cancer dans ce contexte. Methodologie. Il s’agit d’une etude retrospective incluant tous les cas de cancer broncho-pulmonaire primitif, diagnostiques dans les laboratoires d'anatomie et de cytologie pathologique de Dakar, sur une periode de 5 ans. Resultats. Nous avons recense 161 patients dont 86,2 % d’hommes. Les sujets âges de 60 ans et plus (50%) et ceux provenant de la population active (44,1%) etaient les plus touches. Les fumeurs actifs representes 87,5% des cas renseignes, dont un nombre moyen de paquets-annee chiffre a 42,9. Les biopsies constituaient l’essentiel des prelevements (96,3%). Le type histologique predominant etait l’adenocarcinome (45,3%). Il touchait davantage les femmes (64,3%), essentiellement âgees. Conclusion. Le cancer broncho-pulmonaire primitif au Senegal touche autant les sujets âges que la population active, surtout tabagique et se caracterise par une predominance des adenocarcinomes affectant plus les femmes âgees. Il est souvent diagnostique a un stade inoperable. La prevention primaire, le diagnostic precoce et l’etude des facteurs de risque et alterations moleculaires sont de mise. ABSTRACT Introduction. Primary bronchopulmonary cancer is a public health problem, and its histological features are largely unknown in Senegal. The aim of our study was to describe the epidemiology and the histological aspects of this cancer in our country. Methods. This was a cross sectional retrospective study carried out between January 2013 and December 2017, including all cases of primary bronchopulmonary cancer, diagnosed in the anatomy and pathological cytology laboratories in Dakar. Results: We recruited 161 patients, 86.2% of whom were men. Those aged 60 and over (50%) and those from the active population (44.1%) were the most affected. Active smokers represented 87.5% of the reported cases, with an average number of pack-years of 42.9. Biopsies made up the bulk of the samples (96.3%). The most common histological type was adenocarcinoma (45.3%), which most affected women (64.3%) who were usually elderly. Conclusion: Primary bronchopulmonary cancer in Senegal affects both the elderly and the active population, especially tobacco users. Adenocarcinoma is the most common histology and is affects more commonly older women. It is often diagnosed at an inoperable stage. Primary prevention, early diagnosis and study of risk factors and molecular alterations are essential.
Background: Sinonasal hemangiomas are rare, especially hemangiomas of the sphenoid sinus, for which very few cases have been reported. Observation:We report the case of a 20-year-old patient who had consulted for epistaxis associated with headache.A CT scan of the nose and sinuses revealed a heterogeneous tumor process filling the sphenoid sinus.A minimally invasive endonasal surgery under endoscopic guidance allowed complete removal of the tumor.The histological study of the surgical specimen had revealed capillary hemangioma.After 27 months of decline, no recurrence was noted. Conclusion:Capillary hemangioma is very rare in its sphenoidal location.Endonasal endoscopic excision allows optimal control, after a good pre-operative evaluation.
Background: Objectives of the study were to record the results of uterine cervical smear tests of women in the Diourbel region to compare epidemiological data with the results of uterine cervical smear tests.Methods: This was a retrospective study of 201 satisfactory cervical smears performed in the period from 01 December 2018 to 01 December 2019 at the laboratory of the regional hospital Henrich Lubcke of Diourbel. All women with a satisfactory smear were included in our study, so we classified patients according to age and parity.Results: The mean age of the patients was 38.41 years with a standard deviation of 11.51 years. The extremes were 15 and 64 years. The age group (30-40 years) was in the majority at 32.34%. Multiparous patients were in the majority, accounting for 43.28%. The cervix was macroscopically healthy in 61.19% of patients and inflammatory in 12.94%. There was 18.41% low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL) accounted for 1% of smears. A statistically significant relationship existed between parity and smear result with p˂0.01.Conclusions: Cervical cancer is one of the most fatal cancers in women and the smear remains the safest and most effective means of prevention.
Rhabdomyosarcoma (RMS) belongs to the soft tissue sarcomas that have striated muscle differentiation. It is most common in young children under 5 years of age and adolescents. The definite diagnosis of rhabdomyosarcoma is based on histology and the positivity of striated muscle markers in immunohistochemistry. Our objective was to describe the prognostic characteristics of RMS diagnosed in Dakar. MATERIAL AND METHODS: This was a retrospective and descriptive study spread over nine (09) years from 1 January 2011 to 31 December 2019. It was conducted from the histological report archives of the anatomy and pathology laboratories of Dakar. Paraffin blocks were reread and immunohistochemically studied by manual method. Antidesmin and antimyogenin antibodies were used. RESULTS: We collected 44 patients with rhabdomyosarcoma out of 228 cases of soft tissue cancers, i.e. 19.29% of all malignant soft tissue tumours. The mean age of the patients was 25.41 ± 23.95 (standard deviation) years with a median age of 16 years and extremes of 6 months and 81 years. Patients were less than or equal to 17 years of age in 61.4% of cases. A clear male predominance was observed with 29 men (65.9%) against 15 women (34.1%). Rhabdomyosarcomas were located in the limbs in 34.1% of cases, in the head and neck in 29.5% of cases and in the genitourinary tract in 25% of cases. The average tumour size was 7.45 cm ± 4.64 (standard deviation) with a minimum of 2 cm and a maximum of 17 cm. It was greater than or equal to 5 cm in 15 patients (68.2%). Embryonal rhabdomyosarcoma (ERMS) was the most frequent histological type with 34 cases (77.3%), followed by pleomorphic rhabdomyosarcoma 7 cases (15.9%) and alveolar rhabdomyosarcoma 3 cases (6.8%). The histological subtypes of ERMS consisted of conventional ERMS (91.18%); botryoid RMS (5.88%) and spindle cell RMS (2.94%). The correlation between histological type and age was statistically significant (p = 0.039). A relationship was also observed between histological type and site (p = 0.026). According to the American IRS classification, the tumour was classified as group I in 41% of cases, group II in 50% of cases and groups III and IV in 4.5% each. CONCLUSION: Rhabdomyosarcoma is a rare malignant tumour in Dakar. It is often a voluminous tumour of the limbs which affects mainly males. The embryonal type is the most frequent histological form.
Intestinal metaplasia of the bladder is a rare pathology, estimated at less than 1% of bladder pathologies. Some forms, including pseudo tumor glandular cystitis, can mimic cancer. We report a rare case of this pathology, little studied in our context, treated in Senegal and we underline the epidemiologicalclinical and anatomopathological particularities.
'%3e%3cg id='b'%3e%3cpath id='a' d='M0-100V0h50z' transform='rotate(18 0 -100)'/%3e%3cuse xlink:href='%23a' transform='scale(-1 1)'/%3e%3c/g%3e%3cuse xlink:href='%23b' transform='rotate(72)'/%3e%3cuse xlink:href='%23b' transform='rotate(144)'/%3e%3cuse xlink:href='%23b' transform='rotate(216)'/%3e%3cuse xlink:href='%23b' transform='rotate(288)'/%3e%3c/g%3e%3c/svg%3e)
