Perry T. Kaye

Rhodes University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Benzodiazepine analogues. Part 18—13C NMR analysis of Schmidt rearrangement products from flavonone analogues

Magnetic Resonance in Chemistry (1998)

Malose J. Mphahlele Perry T. Kaye

13C NMR spectra of 1,4- and 1,5-benzoheterazepinones and their tetrazolo derivatives, prepared by the Schmidt rearrangement of flavanone analogues, are reported. The effects of the C-ring heteroatoms on the 13C NMR chemical shifts of the ring-expanded products were found to be of diagnostic value in distinguishing the isomeric products from one another and from the corresponding precursors. © 1998 John Wiley & Sons, Ltd.

Heteroatom

Flavanone

Chemical shift

10.1002/(sici)1097-458x(199801)36:1<69::aid-omr219>3.0.co;2-s

Cite

Citations (5)

ChemInform Abstract: Chiral Organosilicon Compounds. Part 5. Structure of (Cholest-5-en-3. beta.-yloxy)(3,3-dimethylbuten-2-yloxy)dimethylsilane.

ChemInform (1992)

Robin B. English Perry T. Kaye Robin A. Learmonth

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Dimethylsilane

Organosilicon

BETA (programming language)

10.1002/chin.199203235

Cite

Citations (0)

ChemInform Abstract: PREPARATION OF NITRILES BY DEHYDRATION OF PRIMARY CARBOXAMIDES WITH A SUPPORTED PHOSPHORUS PENTOXIDE REAGENT

Chemischer Informationsdienst (1985)

Delene A. Kaiser Perry T. Kaye Lavinthren Pillay Gregory Roos

Phosphorus pentoxide

10.1002/chin.198505174

Cite

Citations (0)

Synthesis and biological screening of diethyl [N-(thiazol-2-yl)carbamoyl]methylphosphonates

ARKIVOC (2018)

Emmanuel O. Olawode Roman Tandlich Earl Prinsloo Michelle Isaacs Heinrich C. Hoppe

A three-step synthesis, involving condensation of bromomethyl aryl ketones with urea to afford 2aminothiazoles, their chloroacetylation and subsequent solvent-free Arbuzov phosphonation has afforded a series of novel diethyl [N-(thiazol-2-yl)carbamoyl]methylphosphonates 3a-3f in good overall yields; the 4carboxythiazole analogue 3g was obtained by selective hydrolysis of the corresponding ethyl ester 3f.The phosphonate esters exhibited significant anti-cancer activity (nM -low µM IC 50 values) against SH-SY5Y cells and, in one case, 7.6 µM MIC90 anti-TB activity against the virulent M. tuberculosis H 37 Rv strain; the chloroacetamido precursors all exhibited some antimalarial (PfLDH) activity, three with IC 50 values in the range 1.0 -8.9 µΜ.

10.24820/ark.5550190.p010.534

Cite

Citations (1)

CCDC 198720: Experimental Crystal Structure Determination

The Cambridge Structural Database (2005)

Kevin A. Lobb Perry T. Kaye

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Crystal (programming language)

10.5517/cc6nsby

Cite

Citations (0)

13C nuclear magnetic resonance spectra of the Senecio alkaloids, retrorsine, swazine, isoline, and hygrophylline

Journal of the Chemical Society. Perkin transactions I/Journal of the Chemical Society. Perkin transactions. I (1981)

Siegfried E. Drewes Ivan Antonowitz Perry T. Kaye P. C. COLEMAN

Examination of the 13C n.m.r. spectra of retrorsine and its hydrolysis products has permitted a complete 13C n.m.r. analysis of this alkaloid and the related pyrrolizidine alkaloids swazine, isoline, and hygrophylline.

Pyrrolizidine alkaloid

10.1039/p19810000287

Cite

Citations (17)

CCDC 639803: Experimental Crystal Structure Determination

The Cambridge Structural Database (2007)

Nceba Magqi Kevin A. Lobb Perry T. Kaye Mino R. Caira

10.5517/ccpgrtp

Cite

Citations (0)

ChemInform Abstract: Regio‐ and Diastereoselectivity in the Thiomethylation of α‐(1‐Hydroxyalkyl)acrylate Derivatives.

ChemInform (1998)

Philip O. Deane Jeffry Guthrie-Strachan Perry T. Kaye Ruth E. Whittaker

10.1002/chin.199842077

Cite

Citations (0)

Chromone Studies. Part 9.1 Dynamic NMR Analysis of Rotational Isomerism in 2-(N,N-Dialkylamino)chromones

Journal of Chemical Research Synopses (1997)

Perry T. Kaye Isaiah D. I. Ramaite

Dynamic 1H NMR spectroscopy has been used to explore the influence of substituents on the internal rotation of the amino group in a series of twelve 2-(N,N-dialkylamino)chromones; the rotational barriers (ΔG‡) in CDCl3 and CD2Cl2 were found to range from 38 to 52 kJ mol-1.

Chromone

10.1039/a702801f

Cite

Citations (2)

Aldol Condensation Reactions Effectively Catalysed by Lewis Acid

Acta Chemica Iasi (2017)

Yusuf Hassan Rosa Klein Perry T. Kaye

Abstract A complex of manganese (III) and R,R-1,2-Diaminocyclohexane linked ketopinic acid ligand was synthesized and utilised as catalyst in the aldol condensation reactions of benzaldehyde with various aliphatic ketones to furnish products with excellent yield of > 99%.

Benzaldehyde

Aldol condensation

Aldol reaction

Lewis acid catalysis

Condensation reaction

10.1515/achi-2017-0007

Cite

Citations (2)