Ricardo Gomes da Rosa

Universidade Federal do Rio Grande do Sul

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Vera Lucia Eifler‐Lima

Universidade Federal do Rio Grande do Sul

Cedric Stephan Graebin

Universidade Federal Rural do Rio de Janeiro

Ana Néry Furlan Mendes

Universidade Federal do Espírito Santo

José Ribeiro Gregório

Universidade Federal do Rio Grande do Sul

Hugo Cerecetto

Universidad de la República

Maria de Fátima Madeira

Universidade de São Paulo

Diego Benítez

Institut Pasteur de Montevideo

Jones Limberger

Pontifical Catholic University of Rio de Janeiro

Silvana I. Wolke

Universidade Federal do Rio Grande do Sul

Michèle O. de Souza

Universidade Federal do Rio Grande do Sul

Cooperative Institutions

Universidade Federal do Rio Grande do Sul

Universidade Federal de Ciências da Saúde de Porto Alegre

Universidade Estadual de Campinas (UNICAMP)

Universidade Federal do Rio Grande

Universidade de São Paulo

Rede de Química e Tecnologia

University of Lisbon

Centre National de la Recherche Scientifique

Universidad de la República

Universidade Nova de Lisboa

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Oligomerização e cooligomerização de alfa-olefinas catalizadas por sistemas do tipo ziegler-natta a base de complexos de niquel

Ricardo Gomes da Rosa

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Synthesis of limonene β-amino alcohol derivatives in support of new antileishmanial therapies

Memórias do Instituto Oswaldo Cruz (2008)

Stela Regina Ferrarini Cedric Stephan Graebin Jones Limberger Rômulo FS Canto Daiane O Dias

A series of seven limonene β-amino alcohol derivatives has been regioselectively synthesised in moderate to good yields. Two of these compounds were found to be significantly effective against in vitro cultures of the Leishmania (Viannia) braziliensis promastigote form in the micromolar range. The activities found for 3b and 3f were about 100-fold more potent than the standard drug, Pentamidine, in the same test, while limonene did not display any activity. This is the first report of antileishmanial activity by limonene β-amino alcohol derivatives.

Pentamidine

10.1590/s0074-02762008000800005

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Citations (14)

Rhodium-catalyzed carbonylation of allylaminoalcohols: Catalytic synthesis of N-(2-hydroxy-alkyl)-gamma-lactams and bicyclic oxazolidines

Journal of Molecular Catalysis A Chemical (2008)

Jones Limberger Melina Mottin F.F. Nachtigall E.E. Castellano Ricardo Gomes da Rosa

Carbonylation

Catalytic cycle

10.1016/j.molcata.2008.08.005

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Citations (10)

Easy and efficient processes for catalyst recycling and product recovery in organic biphase systems tested in the hydrogenation of hex-1-ene

Chemical Communications (2000)

Ricardo Gomes da Rosa Laura Martinelli Luís Henrique Mendes da Silva Watson Loh

Two organic liquid biphase systems containg poly(ethylene oxide), heptane and either CH2Cl2 or methanol have been tested in the catalytic hydrogenation of hex-1-ene using, respectively, Wilkinsons catalyst and a cationic rhodium complex, both leading to high yields and selectivity, with the latter showing a better performance and enabling easy and efficient product separation and catalyst recycling.

Heptane

Cationic polymerization

Ene reaction

10.1039/a909101g

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Citations (24)

Dipeptide derivatives of primaquine as transmission-blocking antimalarials: effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates.

Pharmaceutical Research (1999)

Maria João Portela Rui Moreira Emília Valente Luís Constantino Jim Iley

Primaquine

Side chain

Blocking (statistics)