Adolfo Valdivia‐Cayoja

Hospital de Clínicas

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Joel M. Montgomery

Centers for Disease Control and Prevention

Shannon Whitmer

Centers for Disease Control and Prevention

Jason H. Malenfant

Centers for Disease Control and Prevention

Nelly Mendoza Loayza

Centro Nacional de Enfermedades Tropicales

Teresa Pérez‐Gutiérrez

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Cinthia Avila Ardaya

Centro Nacional de Enfermedades Tropicales

Trevor Shoemaker

Centers for Disease Control and Prevention

Maria Morales-Betoulle

Centers for Disease Control and Prevention

Stuart T. Nichol

Centers for Disease Control and Prevention

Jonathan S. Towner

Centers for Disease Control and Prevention

Cooperative Institutions

Centers for Disease Control and Prevention

National Center for Emerging and Zoonotic Infectious Diseases

Centro Nacional de Enfermedades Tropicales

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

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Yale University

Onderstepoort Veterinary Academic Hospital

University of Pretoria

Global Viral

Departamento de Epidemiología

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Aspergillus infection of the larynx in a solid organ transplant recipient

Transplant Infectious Disease (2018)

Andrea Wisniowski‐Yáñez Jaqueline Ramírez‐Anguiano Rodrigo Rosado‐Canto Adolfo Valdivia‐Cayoja Teresa Pérez‐Gutiérrez

Abstract Primary laryngeal aspergillosis is a rare condition. Only a few cases have been reported in the past years. Most of them have been reported in healthy patients or with a mild immunocompromised state. We report a case of primary laryngeal aspergillosis in a solid organ transplant recipient ( SOT ), an infection not previously described in this population; we reviewed the published literature in all populations.

Solid organ

10.1111/tid.12900

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Citations (2)

An immunocompromised patient & multiorgan cystic echinococcosis

QJM (2018)

Bruno Ali López Luis Adolfo Valdivia‐Cayoja Pablo F. Belaunzarán-Zamudio Luis Enrique Soto-Ramírez

Cystic echinococcosis

Multiorgan failure

10.1093/qjmed/hcy306

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Citations (1)

Chapare Hemorrhagic Fever and Virus Detection in Rodents in Bolivia in 2019

New England Journal of Medicine (2022)

Roxana Loayza Mafayle Maria Morales-Betoulle Carla Romero Caitlin M. Cossaboom Shannon Whitmer

In June 2019, the Bolivian Ministry of Health reported a cluster of cases of hemorrhagic fever that started in the municipality of Caranavi and expanded to La Paz. The cause of these cases was unknown.We obtained samples for next-generation sequencing and virus isolation. Human and rodent specimens were tested by means of virus-specific real-time quantitative reverse-transcriptase-polymerase-chain-reaction assays, next-generation sequencing, and virus isolation.Nine cases of hemorrhagic fever were identified; four of the patients with this illness died. The etiologic agent was identified as Mammarenavirus Chapare mammarenavirus, or Chapare virus (CHAPV), which causes Chapare hemorrhagic fever (CHHF). Probable nosocomial transmission among health care workers was identified. Some patients with CHHF had neurologic manifestations, and those who survived had a prolonged recovery period. CHAPV RNA was detected in a variety of human body fluids (including blood; urine; nasopharyngeal, oropharyngeal, and bronchoalveolar-lavage fluid; conjunctiva; and semen) and in specimens obtained from captured small-eared pygmy rice rats (Oligoryzomys microtis). In survivors of CHHF, viral RNA was detected up to 170 days after symptom onset; CHAPV was isolated from a semen sample obtained 86 days after symptom onset.M. Chapare mammarenavirus was identified as the etiologic agent of CHHF. Both spillover from a zoonotic reservoir and possible person-to-person transmission were identified. This virus was detected in a rodent species, O. microtis. (Funded by the Bolivian Ministry of Health and others.).

Christian ministry

10.1056/nejmoa2110339

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Citations (25)