Faraz Quraishi

Rutgers, The State University of New Jersey

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Rania Aziz

Rutgers, The State University of New Jersey

Ming Xiong

Rutgers New Jersey Medical School

Molly Amin

Rutgers New Jersey Medical School

Leanne Haroun

Rutgers New Jersey Medical School

Anuradha Patel

Monroe Carell Jr. Children's Hospital

Cooperative Institutions

Rutgers, The State University of New Jersey

Rutgers New Jersey Medical School

Sichuan University

West China Hospital of Sichuan University

First Affiliated Hospital of Jiangxi Medical College

Nanchang University

Second Affiliated Hospital of Nanchang University

Hubei Polytechnic University

State Key Laboratory of Biotherapy

Chinese PLA General Hospital

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Anaesthetic considerations in a 15 month old with Patau's Syndrome: a case report and review of the literature

Anaesthesia Cases (2017)

Molly Amin Leanne Haroun Faraz Quraishi Rania Aziz Anuradha Patel

Summary Patau's syndrome, trisomy 13, is associated with multiple abnormalities of various organ systems, all of which present a challenge to the anaesthetist. Mortality in infancy is high; therefore there are few published reports regarding the anaesthetic management of patients with Patau's syndrome. Our case report describes the anaesthetic management for a 15‐month‐old male who underwent elective cleft palate repair and we review previous published cases. Anaesthetic considerations and the common abnormalities found in Trisomy 13, such as craniofacial, cardiac and renal defects are discussed.

Trisomy

Craniofacial surgery

Local anaesthetic

10.21466/ac.acia1mo.2017

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A Review of Anesthetic Effects on the Developing Brain - Animal versus Human Models

Journal of Neonatal Biology (2016)

Faraz Quraishi Ming Xiong

In the last 30 years a large amount of data, both animal and human, has come out indicating that perhaps the most commonly used general anesthetics (inhaled anesthetics such as nitrous oxide and iso/sevo/desflurane, but also propofol) may have an effect on the neurodevelopment of an unborn fetus. The neurotoxic effects of volatile anesthetics have been tested numerous times in animal models ranging from rats to primates, and there is a large amount of reliable data which have confirmed that these agents do, in fact, cause interruption and even degeneration of neuronal development, with clinically significant cognitive and behavioural changes neonatal. Does this data apply to the human model?

Omics

Animal model

10.4172/2167-0897.1000240

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