Jiangnan Peng

Morgan State University

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Mark T. Hamann

Medical University of South Carolina

Susan L. Mooberry

The University of Texas Health Science Center at San Antonio

Michelle Kelly

National Institute of Water and Atmospheric Research

April L. Risinger

The University of Texas Health Science Center at San Antonio

Shagufta Perveen

Government College University, Faisalabad

Jin‐Feng Hu

Fudan University

C.C. Rohena

University of California, San Diego

SL Mooberry

The University of Texas Health Science Center at San Antonio

Robert H. Cichewicz

University of Michigan–Ann Arbor

AL Risinger

The University of Texas Health Science Center at San Antonio

Cooperative Institutions

University of Mississippi

The University of Texas Health Science Center at San Antonio

Morgan State University

Universitas Gadjah Mada

Chinese Academy of Sciences

King Saud University

Centre National de la Recherche Scientifique

University of Illinois Chicago

Central South University

Université Toulouse III - Paul Sabatier

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[Chemical investigation of genus Hedyotis. II. Isolation and identification of iridoids from Hedyotis chrysotricha].

PubMed (1997)

Jiangnan Peng Feng Xz Li Gy Liang Xt

Many species of genus Hedyotis (Rubiaceae) were used as folk medicine for treatment of cold, inflammation, cancer and etc. in China. The alcoholic extract of the whole plant of H. chrysotricha showed good hepatoprotective effects. From the alcoholic extract ten iridoids were isolated and their structures were elucidated as: asperuloside (1), scandoside methyl ester (2), asperulosidic acid (3), deacetyl asperulosidic acid (4), loganin (5), deacetyl asperuloside (6), acetyl scandoside methyl ester (7), 6 beta-hydroxy-genipin (8) and two new compounds named hedyoside (9) and 6'-acetylasperuloside (10), by means of chemical and spectral methods.

Loganin

Folk medicine

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Citations (9)

CCDC 1420620: Experimental Crystal Structure Determination

The Cambridge Structural Database (2016)

Shengxin Cai April L. Risinger Shalini Nair Jiangnan Peng Timothy J. C. Anderson

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Crystal (programming language)

10.5517/ccdc.csd.cc1jp8gy

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Recognizing pioneering Black plant scientists in our schools and society

Trends in Plant Science (2021)

Maxwell Eckelbarger Selena L. Rice Anne Osano Jiangnan Peng Hemayet Ullah

Plant science

Plant Diversity

10.1016/j.tplants.2021.07.021

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Citations (1)

Isochlorogenic Acid Glucosides from the Arabian Medicinal Plant Artemisia sieberi and Their Antimicrobial Activities

Molecules (2023)

Khlood Jamal Areej Mohammad Al‐Taweel Sarah I. Bukhari Raha Orfali Nadine Moubayed

A phytochemical investigation of the stems of the Arabian plant Artemisia sieberi afforded three new isochlorogenic acid derivatives, namely isochlorogenic acid A-3'-O-β-glucopyranoside (1), isochlorogenic acid A-3'-O-β-glucopyranoside methyl ester (2), and isochlorogenic acid C-3'-O-β-glucopyranoside (3), obtained along with thirteen known secondary metabolites belonging to distinct structural classes. The structures of the new metabolites were elucidated by modern spectroscopic techniues based on high-resolution mass spectrometry (HR-ESIMS) and 1D/2D nuclear magnetic resonance (NMR). All isolated compounds were tested for their potential antimicrobial activity against four different bacterial strains (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa), in addition to a fungal strain (Candida tropicalis), The results were expressed as the diameter of the clear zone (in millimetres) around each well. Compounds 1 and 3 (isochlorogenic acid A-3'-O-β-glucopyranoside and isochlorogenic acid C-3'-O-β-glucopyranoside, respectively) displayed remarkable antifungal effect and potent antibacterial activities against B. subtilis and S. aureus, respectively. 3α,4α-10β-trihydroxy-8α-acetyloxyguaian-12,6α-olide (6) and angelicoidenol 2-O-β-d-glucopyranoside (9) emerged as interesting dual antibacterial (selective on P. aeruginosa)/antifungal agents.

Phytochemical

10.3390/molecules28227460

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Citations (1)

Corrigendum to “Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms”: [Chemical Review 108 (2008) 264−287]

Chemical Reviews (2009)

Hui Fan Jiangnan Peng Mark T. Hamann Jin‐Feng Hu

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrigendum to "Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms": [Chemical Review 108 (2008) 264−287]Hui Fan, Jiangnan Peng, Mark T. Hamann, and Jin-Feng Hu*Cite this: Chem. Rev. 2010, 110, 6, 3850Publication Date (Web):October 16, 2009Publication History Received26 September 2009Published online16 October 2009Published inissue 9 June 2010https://pubs.acs.org/doi/10.1021/cr900322fhttps://doi.org/10.1021/cr900322fcorrectionACS PublicationsCopyright © 2009 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2179Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (46 KB) Get e-AlertscloseSUBJECTS:Cell physiology,Chemical structure,Inhibitors,Organic compounds,Photocyclization Get e-Alerts

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10.1021/cr900322f

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Citations (36)

The Marine Bromotyrosine Derivatives

ChemInform (2007)

Jiangnan Peng Jing Li Mark T. Hamann

10.1002/chin.200730231

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Citations (2)

New Manzamine Alkaloids from an Indo-Pacific Sponge. Pharmacokinetics, Oral Availability, and the Significant Activity of Several Manzamines against HIV-I, AIDS Opportunistic Infections, and Inflammatory Diseases

Journal of Medicinal Chemistry (2004)

Muhammad Yousaf Nicholas L. Hammond Jiangnan Peng Subagus Wahyuono Kylie A. McIntosh

12,28-Oxamanzamine A (1), 12,28-oxa-8-hydroxymanzamine A (2), and 31-keto-12,34-oxa-32,33-dihydroircinal A (3) were isolated from two collections of an Indo-Pacific sponge, and their structures were assigned on the basis of 1D and 2D NMR spectroscopic data. These compounds possess a novel manzamine-type ring system generated through a new ether bridge formed between carbons 12 and 28 or between carbons 12 and 34 of the typical manzamine structure and add to our growing understanding of manzamine SAR and metabolism. Based on molecular modeling studies, the formation of these oxidation products is highly sterically favored. The potent antiinflammatory, antifungal, and anti-HIV-1 activity for a number of previously reported manzamines is also presented in addition to the pharmacokinetic studies of manzamine A (5). Oral and intravenous pharmacokinetic studies of manzamine A in rats indicated the compound to have low metabolic clearance, a reasonably long pharmacokinetic half-life, and good absolute oral bioavailability of 20.6%, which supports the value of these compounds as potential leads for further preclinical assessment and possible development.

Sponge

Indo-Pacific

10.1021/jm030475b

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Citations (111)

Bromopyrrole Alkaloids from the Jamaican Sponge Didiscus oxeata

ChemInform (2005)

Jin‐Feng Hu Jiangnan Peng Abul B. Kazi Michelle Kelly Mark T. Hamann

Abstract For Abstract see ChemInform Abstract in Full Text.

Sponge

10.1002/chin.200550184

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Citations (0)

Further Studies on New Furostanol Saponins from the Bulbs of Allium macrostemon.

Chemical and Pharmaceutical Bulletin (1994)

Jiangnan Peng Xin‐Sheng Yao Yoshihito Okada Toru Okuyama

Further studies by means of preparative HPLC led to the isolation of two new furostanol saponins, macrostemonoside J (1) and L (3), along with an artifact, macrostemonoside K (2) from the bulbs of Allium macrostemon. On the basis of chemical evidence and spectral analysis (1H-, 13C-NMR and FAB-MS), the structure of 1 was elucidated to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,22,26-tetrahydroxy-25(R)-5 beta-furostan 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside. 3 was deduced to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,26-trihydroxy-25(R)-5 beta-furostan- 20(22)-ene 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside.

Spectral Analysis

Liliaceae

10.1248/cpb.42.2180

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Citations (31)

ChemInform Abstract: Reductive Amidation of Nitroarenes: A Practical Approach for the Amidation of Natural Products.

ChemInform (2009)

Amir E. Wahba Jiangnan Peng Mark T. Hamann

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.200941074

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