K.‐E. Kreus

University of Oulu

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Lung Transplantation and Pulmonary Arteriolar Circulation

Scandinavian Journal of Thoracic and Cardiovascular Surgery (1970)

Pentti Ketonen S Mattila Leena Siirilä K.‐E. Kreus

The pathophysiological basis of the increase in pulmonary vascular resistance associated to lung transplantation has not been indisputably clarified. The purpose of the present work was to study the effect of lung transplantation on the pulmonary circulation at the ar-teriolar level. Autotransplantation of the left lung was performed on 9 mongrel dogs. Pulmonary arteriolar pulsation was measured by cinédensitography before and after autotransplantation. The aortic, pulmonary arterial and venous and left atrial pressures, as well as ECG, were recorded simultaneously. A comparison was made between the simultaneous arteriolar pulsation curves of the transplanted left and intact right lungs. The operation produced a fall in the aortic and pulmonary arterial pressures and an increase in the pulse rate due to blood loss during the operation, but no notable pressure gradients in pulmonary arterial or venous anastomoses. The autotransplantation caused a slight, but not significant, decrease in the arteriolar pulsation of the transplanted lung as compared with the intact contra-lateral lung. It was, therefore, concluded that the increase in pulmonary vascular resistance observed in earlier investigations could not be explained on the basis of an impaired distensibility of the pulmonary arterioles.

Autotransplantation

10.3109/14017437009134249

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Citations (2)

Pulmonary Sequestration and Pterygium Colli Syndrome

Scandinavian Journal of Thoracic and Cardiovascular Surgery (1971)

S Mattila L Virkkula K.‐E. Kreus

AbstractA rare case of a male pterygium colli syndrome associated with an extralobar pulmonary sequestration is reported. The patient had webbed neck, low-set ears, low-set hair line, aplasia of the left kidney and hypoplastic mesenterial vessels referring to Turner's syndrome, but a normal XY sex chromosome constitution. The pulmonary sequestration was resected and the patient made an uneventful recovery.

Pterygium

10.3109/14017437109134282

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Citations (0)

Disodium cromoglycate in exercise-induced asthma.

BMJ (1969)

A Muittari K.‐E. Kreus

Disodium cromoglycate

Sodium cromoglycate

Exercise-induced asthma

10.1136/bmj.4.5676.170-a

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Citations (17)

Non‐synchronized Direct Current Countershock

Acta Medica Scandinavica (1965)

E. Waris T. M. Scheinin K.‐E. Kreus Juhani Salokannel B. Scheinin

10.1111/j.0954-6820.1965.tb04275.x

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Citations (5)

Recurrent ventricular tachycardia.

Heart (1969)

Juhani Salokannel E. Waris K.‐E. Kreus

10.1136/hrt.31.4.517

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Citations (6)

Fatal Cytomegalovirus Disease in a Previously Healthy Adult

Scandinavian Journal of Infectious Diseases (1972)

E. Waris O. Räsänen K.‐E. Kreus R Kreus

A woman, aged 43, developed symptoms of congestive heart failure apparently due to myocarditis. Signs of encephalitis, subacute hepatitis and adrenal insufficiency were noted during the disease. There was a 4-fold rise in complement-fixing antibodies to cytomegalovirus (CMV) and large intranuclear inclusion-bearing cells were found in the urine. The patient died after 7 months. At autopsy were found changes apparently due to CMV myocarditis and a possibly specific inflammation of the adrenals. The liver showed subacute hepatitis, while no specific changes were seen in the brain or in other organs.

Cytomegalovirus

Viral Hepatitis

10.3109/inf.1972.4.issue-1.13

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Citations (27)

ALPRENOLOL IN THE TREATMENT OF ARRHYTHMIAS IN ACUTE CORONARY PATIENTS

Acta Medica Scandinavica (1970)

K.‐E. Kreus S. J. Salokannel H Isomäki E. Waris

Abstract. Alprenolol, a beta‐receptor blocking agent with a slight intrinsic beta‐receptor stimulating effect, has been given to 15 acute coronary patients intravenously for treatment of acute arrhythmias. The results were successful in one case out of three with atrial fibrillation, in none of the three cases with ventricular tachycardia, in three cases out of four with supraventricular tachycardia, in three cases out of four with ventricular ectopic beats, and unsuccessful in the only atrial flutter case. In four cases the injection of 2.5–5.0 mg of alprenolol resulted in sudden circulatory collapse and clinical shock. In all these cases the blood pressure was readily restored with metaraminol or noradrenaline infusion without complications. It is evident that the beta‐receptor stimulating effect is not sufficient to compensate the drawbacks of beta‐blockade in this drug. Alprenolol cannot be recommended in the treatment of arrhythmias in acute coronary patients.

Alprenolol

Metaraminol

Supraventricular arrhythmia

10.1111/j.0954-6820.1970.tb08053.x

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Citations (7)

Body Plethysmographic Studies in Non-Smoking, Healthy Adults

Scandinavian Journal of Clinical and Laboratory Investigation (1982)

A. A. Viljanen B. C. Viljanen P. K. Halttunen K.‐E. Kreus

Reference values for Raw, SGaw, FRC, VC, RV, TLC, RV/TLC and ERV were measured in a series of 268 non-smoking males and 244 non-smoking females, all 18 – 65 years old.The measurements were taken with a constant-volume body plethysmograph (Siregnost, Siemens), using an analog computer to correct differences in temperature and humidity.Equations were derived using age, height and weight as predictors. The reproducibility was tested.

Plethysmograph

10.1080/00365518209168379

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Citations (11)

The Peripheral Lung Pulse and Bronchial Circulation

Scandinavian Journal of Thoracic and Cardiovascular Surgery (1971)

K.‐E. Kreus S Mattila Pentti Ketonen

The recording of the peripheral lung pulse by cinedensigraphy has been used to an increasing extent in the study of the regional pulmonary perfusion. The intensity of pulsation, expressed as pulsation index, has been used as synonymous with the blood flow and psr-fusion. Nothing, however, is known about the contribution of the bronchial circulation to the form and amplitude of the cinedensigraphic pulse. The purpose of the present study was to clarify this experimentally. The bronchial vessels of the right lungs of ten mongrel dogs were divided and the cinedensigraphic pulses of both lungs were recorded before and after severance of the vessels. It was noted that the pulmonary parenchymal pulsation did not show any significant change in form or amplitude after interruption of the bronchial circulation. Therefore the cinedensigraphic pulse, reflecting the intensity of the pulmonary arterial blood flow, is unaffected by the bronchial circulation.

Peripheral vessels

Circulation (fluid dynamics)

Parenchyma

Intensity

10.3109/14017437109135548

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Citations (0)

Body plethysmographic studies in non-smoking, healthy adults.

PubMed (1982)

A. A. Viljanen B. C. Viljanen P. K. Halttunen K.‐E. Kreus

Plethysmograph

Source

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Citations (30)