Mónica Patricia Caicedo-Verástegui

Universidad de Los Andes

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Luis Gerardo García-Herreros

Fundación Santa Fe de Bogotá

Aylen Vanessa Ospina

Fundación Santa Fe de Bogotá

Diana Palacios

Universidad Nacional Autónoma de México

Alfredo Saavedra

Instituto Nacional de Salud

Margarita Baldión

Fundación Santa Fe de Bogotá

Javier Leonardo Galindo

Hospital Universitario Mayor, Mederi

Darı́o Londoño

Fundación Santa Fe de Bogotá

Adriana Galeano

Pontificia Universidad Javeriana

Ana Milena Callejas

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

David A. Suárez-Zamora

Fundación Santa Fe de Bogotá

Cooperative Institutions

Fundación Santa Fe de Bogotá

Universidad Nacional de Colombia

Universidad de Los Andes

Asociación Colombiana de Neumología y Cirugía de Tórax

Instituto Nacional de Cancerología

Hospital Universitario Nacional de Colombia

Hospital Universitario San Ignacio

Pontificia Universidad Javeriana

Universidad El Bosque

Instituto de Investigación Sanitaria de Santiago

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Comparison of the QuantiFERON-TB and tuberculin skin test for detection of latent tuberculosis infection in cancer patients in a developing country

ERJ Open Research (2019)

Javier Leonardo Galindo Adriana Galeano David A. Suárez-Zamora Ana Milena Callejas Mónica Patricia Caicedo-Verástegui

Cancer patients have an increased risk of reactivation of latent tuberculosis infection. It is unknown which strategy on screening should be used in this population in developing countries. We aimed to determine the concordance between the tuberculin skin test (TST) and QuantiFERON ® -TB (QFT) assay in order to diagnose latent tuberculosis infection in cancer patients. We conducted a cross-sectional study of the agreement of diagnostic tests. Prevalence and agreement between tests were calculated. A logistic regression to assess predictors of discordance was performed. The accuracy of the TST to predict QFT results by a receiver operating characteristic (ROC) curve was evaluated. We included 149 adults with cancer without active tuberculosis. Prevalence of latent tuberculosis infection was 21.5% (n=32), defined as positive results on either test. Test agreement was moderate for the diagnosis of latent tuberculosis infection (κ=0.43, 90% CI 0.26–0.6). No predictor was associated with the chance of discordant results. Agreement improved slightly using a cut-off point ≥8 mm (κ=0.5, 90% CI 0.35–0.66). In a moderate-incidence setting, a moderate agreement was found between tests in cancer patients. Modification of the cut-off points of test results achieved marginally better agreement between the TST and QFT.

QuantiFERON

Concordance

Skin test

10.1183/23120541.00258-2018

Cite

Citations (9)