Georgia Chrousos

Washington Center

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Lorenz E. Zimmerman

Armed Forces Institute of Pathology

Martin P. Kolsky

Georgetown University

Jorge C. Kattah

Illinois College

Herbert J. Manz

Georgetown University Medical Center

Allan E. Kolker

Glaucoma Research Foundation

Michael Marmor

New York University

Ralph Dutton

Kathleen Edward

Bernard Becker

Ruhr West University of Applied Sciences

Susanh Davis

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Johns Hopkins University

STMicroelectronics (France)

University of Southern California

Doheny Eye Institute

New York Eye and Ear Infirmary

Smith-Kettlewell Eye Research Institute

University of California, Los Angeles

Iowa City Public Library

Harvard University

Ophthalmology Associates (United States)

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Deleted Journal (1995)

Douglas R. Anderson R Beck Mark S. Blumenkranz James D. Brandt James J. Crawford

10.1016/s0161-6420(14)80008-0

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Bilateral Orbital Involvement in Fatal Giant Cell Polymyositis

Ophthalmology (1990)

Jorge C. Kattah Lorenz E. Zimmerman Martin P. Kolsky Georgia Chrousos Richard M. Chavis

The case of a young woman with giant cell polymyositis is described. She had bilateral, severe, midly painful proptosis and ophthalmoplegia. Extensive pharyngeal, laryngeal, and cardiac muscle involvement occurred 18 months later coincident with fatal cardiac arrhythmia. At autopsy, extensive muscle necrosis and giant cells were noted in extraocular, pharyngeal, laryngeal, and cardiac muscle with only minimal involvement of other striated muscles.

10.1016/s0161-6420(90)32554-x

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Metastatic Prostate Cancer to the Optic Canal

Ophthalmology (1993)

Jorge C. Kattah Georgia Chrousos Joan Roberts Martin P. Kolsky Lorenz E. Zimmerman

Optic neuropathies represent a common cause of blindness among patients with cancer. The authors present the clinical and imaging findings and discuss the management of optic nerve involvement from metastatic prostate cancer to the optic canal.Five patients with advanced metastatic prostate cancer had visual loss. Neuro-ophthalmologic examination and pre- and post-gadolinium orbital and brain magnetic resonance imaging (MRI) were performed. Compressive optic neuropathy secondary to extensive optic canal involvement was demonstrated in all of the patients. Neuropathologic examination was accomplished in two cases. A combination of steroid and focal radiation therapy was used for treatment in four patients.Imaging and neuropathologic findings demonstrated a compressive optic neuropathy secondary to both epidural metastases and to deformity and hypertrophy of the optic canal due to metastatic cancer. Treatment was of benefit in three cases.Acute and subacute unilateral or bilateral optic neuropathy in patients with prostate cancer may be the result of optic canal metastases. Magnetic resonance imaging shows a characteristic pattern of bone hypertrophy and deformity with optic nerve compression. Early combination steroid and radiation therapy may induce long-lasting improvement.

Optic canal

10.1016/s0161-6420(93)31413-2

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Pheochromocytoma and Paraganglioma -- Endotext

Feingold Kr B Anawalt Alison M. Boyce Georgia Chrousos Kia Dungan

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