Objective To investigate the relationship between resistance index(RI) of prostate capsular artery and prostate cancer(PCa).Methods The RI of prostatic capsular artery was measured in 87 patients undergoing transrectal ultrasound-guided needle prostate biopsy.The results were analyzed with those of total proastate specific antigen(tPSA),free/total PSA(f/tPSA) and proastate specific antigen density(PSAD).The cutoff value of RI for diagnosing PCa was determined by ROC curve.Results Of 81 cases,31 patients were diagnosed as PCa and 56 cases were with benign prostatic hyperplasia(BPH).The RI of prostatic capsular artery was higher in PCa patients than that in BPH patients(0.78±0.10 vs.0.72±0.10)P0.05).The values of tPSA,f/tPSA and PSAD were also significantly different between PCa and BPH patients(P0.05).However,higher RI and PSAD were found only in PCa patients among those with gray PSA value(4-10 ng/ml)(P0.05).The best cutoff value determined by ROC curve to diagnose PCa was 0.72.The sensitivity and specificity for diagnosing PCa were 77.4% and 78.6%,respectively,when two cutoff values of RI≥0.72 and PSAD0.15 ng·ml-1·cm-3 were serially combined.Conclusion RI of prostatic capsular artery might have significant clinical value in differentiating PCa from BPH among the patients underwent needle prostate biopsy,especially among those with PSA gray value.The relative high sensitivity and specitivity of diagnosing PCa could be achieved by serially combined detecting RI of prostatic capsular artery and PSAD.
Objective: To evaluate the value of transrectal contrast-enhanced ultrasound(CEUS) in the differential diagnosis of prostate begin and malignant nodules.Methods: Thirty-three patients with 38 nodes were examined with transrectal ultrasound(TRUS) and CEUS.And then nodule-target TRUS guided biopsy was performed on those nodules.After biopsy,datum of CEUS were replayed and time intensity curves(TIC) of regions of interest(ROI) were analyzed with auto tracking contrast quantification(ACQ)software.Several parameters were measured on each nodule.Statistic analyses of all data were performed between the groups divided by pathologic results.Results: Twenty of 38 nodules were benign and the other 18 ones were malignant.Most of prostate cancer nodules showed increased enhancement(14/18).However,the benign nodules mainly showed equal enhancement(14/20).The average time to peak(TTP) and accelerating time(ACT) of malignant nodule,(26.03 ± 3.12) s and(8.22 ± 3.07) s respectively,were shorter than those of benign nodule,(30.98 ± 7.15) s and(12.26 ± 5.30) s,respectively(P 0.05).And peak intensity(PI) of prostate cancer nodule,(20.43 ± 5.32) dB,was lower than that of benign lesion,(23.51 ± 2.51) dB,P 0.05.The difference of two groups had statistical significance.Conclusion: CEUS could reveal the presence of vasculature within the lesions of prostate cancer objectively.TTP,ACT and PI could help to discriminate prostate malignant lesions from benign ones.
Objective To explore the ultrasound diagnostic value in hashimoto thyroiditis(FHT).Methods Gray-scale and color Doppler flow images(CDFI) of 15 FHT patients confirmed by surgery pathology were retrospectively analyzed.Results Fifteen single lesions in the thyroids of 15 FTH patients were detected by gray-scale ultrasound scan.The around parenchyma was well-distributed.Ele-ven(73.3%) of 15 lesions were of well-defined margin.Twelve(80%) of 15 lesions were regular and 12(80%) lesions were hypoechoic.Eight lesions with uneven echogenicity were like the map and were of no significant occupation effect.Hyperechoic calcification was detected in 2(13.3%) lesions.Extremely abundant blood flow sign as focal inferno was showed in CDFIs of 4(26.7%) lesions.Ten(66.7%) of 15 lesions showed mildly abundant blood flow sign and 1(6.7%) lesion had no blood flow sign.Conclusion The FHT has characterized ultrasound appearance and ultrasound is helpful to the clinical diagnosis of FHT.
Objective To evaluate the diagnostic and differential diagnostic effects of ultrasound in testicular tumors and tumor-like lesions.Methods Ultrasound features of 33 cases of testicular masses were reviewed and the results were compared with pathological findings.Results For the 33 cases of testicular masses,12 cases were diagnosed as seminoma,6 cases as lymphoma,6 cases as epidermoid cyst,2 cases as mixed germ cell tumor,2 cases as teratoma,1 case as embryonal carcinoma,1 case as endodermal sinus tumor and 3 cases of the other tumor.Conclusions Ultrasound has important value in the diagnosis and differential diagnosis of testicular tumor and tumor-like lesions,and it can be considered first choice of clinical imaging examination.
Key words:
Testicular tumor; Tumor-like lesions; Ultrasound; Diagnosis and differential diagnosis
Objective To evaluate the value of transrectal contrast enhanced ultrasound(TR-CEUS) in diagnosis of benign and malignant prostatic neoplasms.Methods Sixty patients with elevated level of serum prostate specific antigen and suspected prostate diseases were examined with transrectal uhrasound(TRUS), and TR-CEUS.The pattern and intensity of CEUS in these patients were observed;and the patients with nodules were examined with CEUS guided biopsy and sextant system biopsy after ultrasound imaging.Time-intensity curves (TIC) were drawn to calculate the parameters, and the difference between benign and malignant nodes was compared.Results All sixty prostate patients were confirmed by pathological examination.Thirty-seven patients belong to benign lesions, among them 15 patients with nodule lesion had total 20 nodules, while 22 cases had benign prostatic hyperplasia.In 23 cases of malignant lesions, 18 cases had centralized nodules and 5 cases showed diffuse pathologic changes.Benign nodes of inner gland showed a main pattern of homogenous enhancement and a clear node zone, whereas, malignant nodes displayed significant enhancement in peripheral tissue.The time to peak and accelerating time (ACT) of malignant nodes were shorter than those of benign nodes (P 0.05).The accordance rate of TR-CEUS in the differential diagnosis of benign and malignant prostatic lesions was higher than that of TRUS (P<0.05).In addition, the sensitivity, specificity and accurate rate of TR-CEUS were higher than those of TRUS, whereas, both misdiagnosis and missed diagnosis rate of TR-CEUS were lower than those of TRUS.Conclusions TR-CEUS has clinical value for early discovery of prostatic cancer and has higher application value to differentiate malignant from benign diseases.
Key words:
Endosonography; Microbubbles; Prostatic neoplasms
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