Faculty of Medicine, Department of Pediatrics, Section of Gastroenterology, Hacettepe University, Ankara, Turkey Reprint requests and correspondence: İnci Nur Saltık Temizel, MD, Hacettepe University, Section of Gastroenterology, Faculty of Medicine, Department of Pediatrics, 06100 Ankara, Turkey. Received 15 January 2003; accepted 20 January 2003

Pediatric gastroenterology

University faculty

Reprint

10.1111/j.1572-0241.2003.07510.x

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Citations (1)

Midazolam and Pethidine for the Sedation of Children Undergoing Gastrointestinal Endoscopy

Critical Care Medicine (2000)

Figen Gürakan Aysel Yüce Hasan Özen İnci Nur Saltık‐Temizel

Gürakan, Figen MD; Yüce, Aysel MD; Özen, Hasan MD; Saltik, Inci Nur MD Author Information

Pethidine

Midazolam

10.1097/00003246-200006000-00112

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Citations (2)

Giant Omental Cyst (Lymphangioma) Mimicking Ascites and Tuberculosis

Iranian Journal of Radiology (2016)

Asuman Nur Karhan Tutku Soyer Altan Güneş Beril Talim İbrahim Karnak

Omental and mesenteric cysts are both rare pathologies in children. Children who have omental cysts usually display symptoms of abdominal distension, with or without a palpable mass. The mass can simulate ascites on clinical observation, or tuberculosis on radiological images. The optimal treatment for this condition is complete resection. The presenting symptoms of abdominal distension and the simulation of septated ascites and abdominal tuberculosis are unusual. Reported cases in the literature usually display symptoms of abdominal distension, abdominal pain, painless mass or possible ascites. We describe the clinical presentation of a five-and-a-half-year-old boy who was treated for a diagnosis of abdominal tuberculosis and ascites at another hospital. After three years, he underwent abdominal surgery, and an omental cyst was found intraoperatively. The diagnosis was confirmed by pathological examination.

Abdominal distension

Abdominal mass

Lymphangioma

10.5812/iranjradiol.31943

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Citations (15)

Cytokine profile in serum and gingival crevicular fluid of children with inflammatory bowel disease: A case‐control study

Journal of Periodontology (2021)

Buket Acar Ersin Gümüş Selcen Ozcan Bulut Cansu Özşin‐Özler Meryem Seda Boyraz

Abstract Background To evaluate the cytokine profile in gingival crevicular fluid (GCF) and serum of pediatric inflammatory bowel disease (IBD) patients and determine the cluster patterns of cytokines. Methods Fifty IBD patients and 21 systemically healthy children were enrolled in the study. The GCF samples were collected from the participants during periodontal examination and periodontal indices were recorded. Based on activity indexes and response to conventional treatment, patients with IBD were further categorized into subgroups as: remission, active disease, and treatment‐resistant. Serum samples were obtained from IBD patients to determine serum levels of cytokines. The levels of pro‐ (interleukin (IL)‐1β, IL‐12, IL‐21, IL‐22, IL‐23, IL‐17A, IL‐17F) and anti‐inflammatory (IL‐4, IL‐10) cytokines in serum and GCF were measured using Enzyme‐linked Immunosorbent Assay (ELISA) kits. Results Among 50 IBD patients, 58% were in remission, 20% had active disease, and 22% were defined as treatment‐resistant. The severity of gingival inflammation measured by the criteria of Löe had increasing trends in IBD patients with active disease and treatment resistance. GCF IL‐1β level was lower and GCF IL‐4 and GCF IL‐23 levels were higher in IBD patients compared to healthy controls. In the active disease group, more cytokine clusters occurred compared to the control group and other IBD subgroups, as explained by increased cytokine‐cytokine interactions. Conclusions Considering the increased complexity of cytokine interactions and the increased severity of gingival inflammation in patients with active disease, it can be concluded that disease activity might have an impact on gingival inflammation in pediatric patients with IBD.

10.1002/jper.21-0514

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Citations (6)

Role of flumazenil for paradoxical reaction to midazolam during endoscopic procedures in children

The American Journal of Gastroenterology (2000)

İnci Nur Saltık‐Temizel

Flumazenil

Midazolam

Paradoxical reaction

10.1016/s0002-9270(00)02028-1

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Citations (4)

Comparison of familial and psychological factors in groups of encopresis patients with constipation and without constipation.

PubMed (2015)

Sadriye Ebru Çengel Kültür Devrim Akdemir İnci Nur Saltık‐Temizel

The study aimed to evaluate the differences between groups of encopresis patients with constipation and without constipation. The Symptom Checklist- 90-Revised, the COPE Questionnaire, the Relationship Scales Questionnaire, the McMaster Family Assessment Device and the Parenting Style Scale were used to evaluate, respectively, maternal psychiatric symptoms, coping abilities, attachment style, family functioning and children's perceptions of parenting behaviors. Psychiatric diagnoses were evaluated using the K-SADS. A higher level of maternal psychiatric symptoms, impaired role and affective involvement functioning of the family and less psychological autonomy were observed in the group of encopresis patients with constipation than in the group of encopresis patients without constipation. No significant differences were found between the groups in psychiatric comorbidities, maternal coping abilities and attachment style. The two groups had a similar pattern of comorbid psychiatric disorders and maternal psychological factors, although some familial factors-related mainly to parental authority-were differentiated in the encopresis with constipation group.

Encopresis

Functional constipation

Source

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Citations (4)

Clinical and histopathological features of immunoglobulin G4‐associated autoimmune hepatitis in children

Journal of Gastroenterology and Hepatology (2018)

Yusuf Aydemir Zühal Akçören Hülya Demır İnci Nur Saltık‐Temizel Hasan Özen

We aimed to examine the frequency and the characteristics of immunoglobulin G4 (IgG4)-associated autoimmune hepatitis among pediatric patients with autoimmune hepatitis.Immunostaining for IgG and IgG4 was performed in liver biopsies of 40 pediatric patients with autoimmune hepatitis. The patients with more than 10 IgG4-positive plasma cells/high-power field were defined as IgG4-associated autoimmune hepatitis. Clinic, laboratory, and histopathological results were compared between groups.Among the 40 pediatric patients, 34 patients were type 1 and 6 patients were type 2 autoimmune hepatitis. Six patients (15%), four of the type 1 and two of the type 2 autoimmune hepatitis patients, were diagnosed with IgG4-associated autoimmune hepatitis. Clinical, laboratory, and histopathological data were initially similar in both forms. There was a positive correlation between IgG4-positive plasma cell count and degree of portal (r: 0.406, P: 0.009) and lobular inflammation (r: 0.37, P: 0.019), grade of interface hepatitis (r: 0.33, P: 0.03), and fibrosis (r: 0.318, P: 0.046). Time required for normalization of liver transaminases and serum IgG level was significantly shorter in IgG4-associated autoimmune hepatitis (3.3 ± 0.5 vs 6.6 ± 3.5 for alanine aminotransferase, 3.7 ± 0.8 vs 6.7 ± 1.2 for aspartate aminotransferase, 4.3 ± 1.2 vs 7.1 ± 2.7 for gamma-glutamyl transpeptidase, and 7.2 ± 3.1 vs 12.8 ± 4.5 for IgG).Immunoglobulin G4-associated autoimmune hepatitis can be found in pediatric age group and also in type 2 autoimmune hepatitis patients. As steroid response may be better in IgG4-associated autoimmune hepatitis, biopsy specimens should be evaluated for this entity at diagnosis.

Autoimmune Hepatitis

10.1111/jgh.14525

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Citations (23)

Serum Homocysteine Concentrations In Children With Inflammatory Bowel Disease

Journal of Pediatric Gastroenterology and Nutrition (2004)

Makbule Eren İnci Nur Saltık‐Temizel Nurten Koçak

Inflammatory Bowel Diseases

10.1002/j.1536-4801.2004.tb00804.x

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Citations (0)