Debora Lucia

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Carmen Sílvia Valente Barbas

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Fabı́ola Del Carlo Bernardi

Faculdade de Ciências Médicas da Santa Casa de São Paulo

Berenice B. Mendonça

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Seguro Danilovic

Rodrigo Antônio Brandão-Neto

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Alfredo Nicodemos Cruz Santana

Escola Superior de Ciências da Saúde

Alfredo Nicodemos

Carmen Sílvia

Faculdade de Medicina de São José do Rio Preto

Cooperative Institutions

Universidade de São Paulo

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Hospital de Clínicas

Instituto do Coração

Centro Universitário das Faculdades Metropolitanas Unidas

Hospital Universitário da Universidade de São Paulo

Universidade Brasil

Hospital de Clínicas de Porto Alegre

GTx (United States)

Hospital Israelita Albert Einstein

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

A very rare cause of dyspnea with a unique presentation on a computed tomography scan of the chest: macrophage activation syndrome* Uma rara causa de dispnéia com apresentação singular na tomografia computadorizada de tórax: síndrome de ativação macrofágica

Rodrigo Antônio Brandão-Neto Alfredo Nicodemos Alfredo Nicodemos Cruz Santana Debora Lucia Seguro Danilovic

Macrophage activation syndrome is a rare and potentially life-threatening disease. It occurs due to immune dysregulation manifested as excessive macrophage proliferation, typically causing hepatosplenomegaly, pancytopenia and hepatic dysfunction. Here, we report an unusual case of macrophage activation syndrome presenting as dyspnea, as well as (reported here for the first time) high resolution computed tomography findings of an excavated nodule, diffuse ground glass opacities and consolidations (mimicking severe pneumonia or alveolar hemorrhage). The patient was successfully treated with human immunoglobulin. We recommend that macrophage activation syndrome be considered in the differential diagnosis of respiratory failure. Rapid diagnosis and treatment are essential to achieving favorable outcomes in patients with this syndrome.

Macrophage Activation Syndrome

Rare disease

Hepatosplenomegaly

High-resolution computed tomography

Source

Cite

Citations (0)