Hung‐Chi Lue

National Taiwan University Hospital

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Co-Authors

Mei‐Hwan Wu

National Taiwan University Hospital

138

Jou‐Kou Wang

National Taiwan University Hospital

115

Ing‐Sh Chiu

National Taiwan University Hospital

Ming‐Tai Lin

National Taiwan University Hospital

Chung‐I Chang

National Taiwan University Hospital

Shu‐Hsun Chu

Third Affiliated Hospital of Zhengzhou University

Shyh‐Jye Chen

National Taiwan University Hospital

Shuenn‐Nan Chiu

National Taiwan University Hospital

Chi‐Ren Hung

National Taiwan University Hospital

En‐Ting Wu

National Taiwan University Hospital

Cooperative Institutions

National Taiwan University Hospital

185

National Taiwan University

169

National Yang Ming Chiao Tung University

Taipei Medical University

National Cheng Kung University

Mackay Memorial Hospital

China Medical University

Taipei Veterans General Hospital

Chang Gung Memorial Hospital

Fu Jen Catholic University

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Influence of maturation on diastolic events of left ventricle in children.

PubMed (1992)

Mei‐Hwan Wu Jing‐Ming Wu Sue-Chin Chien Hung‐Chi Lue

To delineate the influence of maturation process on diastolic events of cardiac cycle, we had performed M-mode and Doppler echocardiography in 120 normal subjects aged from 1 hour to 16 years. The isovolumic relaxation period (IVRP, msec), defined as the time interval between the aortic valve closure to the mitral valve opening, was not statistically different in various age groups. Different equations based on individual ranges of cycle length (CL) were disclosed for each of three different age groups, demonstrating a positive linear correlation between IVRP and CL. On the contrary, an equation showing a linear correlation between diastolic total period (DTP, msec) and CL could be applied to all age groups: DTP = 0.58 x CL-75.2 (r = 0.89, p less than 0.001). Similarly applicable to all age groups, the duration of early diastolic filling (D-F, msec) changed with DTP in all age groups by an equation: D-F = 0.57 x DTP + 0.11 (r = 0.93, p less than 0.001). Ratios between the maximal velocity of early (E) and atrial (A) diastolic filling increased gradually with age. This was largely due to an increase in E with maturation, suggesting a depressed early diastolic filling in the young hearts. We conclude that the patterns of diastolic relaxation and filling are heterogeneously affected by the degree of maturation and represent the net results of complex interactions between changing inactivation properties and loading status at various stages.

Isovolumic relaxation time

Cardiac cycle

Age groups

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Citations (2)

Heart Rate by Age

Hung‐Chi Lue

10.1002/9780470995020.ch1

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Citations (0)

Surgical repair of ventricular septal defect with aortic insufficiency.

PubMed (1979)

Tasi Ch Lee Yc Yang Yj Shu‐Hsun Chu Hung Cr

Aortic Valve Insufficiency

Heart septal defect

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Allergic Reactions in Rheumatic Fever Patients on Long-term Benzathine Penicillin G: The Role of Skin Testing for Penicillin Allergy

PEDIATRICS (1996)

Milton Markowitz Hung‐Chi Lue

An injection of 1.2 million U benzathine penicillin G (BPG) every 3 or 4 weeks has proven by far to be the most effective method to prevent recurrences of acute rheumatic fever.1-3 The efficacy of this method of prophylaxis was first demonstrated more than 40 years ago, and since its introduction, it has played a major role in reducing the morbidity and mortality from rheumatic fever.4 Rheumatic fever causes 25% to 40% of all cardiovascular diseases in developing countries.5 Because of the impact of this disease on public health, the World Health Organization (WHO) has helped establish programs for prevention of recurrent attacks of rheumatic fever in many developing countries.6 WHO recommends BPG as the prophylactic drug of choice. One of the problems encountered has been the high drop-out rates among patients enrolled in these programs. Among the reasons for discontinuing prophylaxis is the fear of an allergic reaction.7 The initial study using BPG for the prevention of recurrences of rheumatic fever in children and adolescents reported only 5 (1.2%) mild allergic reactions among 410 patients receiving monthly injections.1 Since then, although rheumatic fever prevention in the United States (U.S.) has consisted almost exclusively of using BPG, there been very few documented reports of serious allergic reactions in rheumatic fever patients on long-term prophylaxis. The only fatalities reported in the American literature occurred in four adults with advanced rheumatic heart disease.8,9 The salutary experience with BPG in the U.S. contrasts sharply with the numerous anecdotal reports of fatal allergic reactions to BPG in many developing countries.

Acute rheumatic fever

10.1542/peds.97.6.981

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Citations (42)

Epidemiological Features of Kawasaki Disease in Taiwan, 1976–2007: Results of Five Nationwide Questionnaire Hospital Surveys

Pediatrics & Neonatology (2013)

Hung‐Chi Lue Lei-Ru Chen Ming‐Tai Lin Luan‐Yin Chang Jou‐Kou Wang

Case fatality rate

10.1016/j.pedneo.2013.07.010

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Citations (41)

Masked gradient of infundibular stenosis in right atrial isomerism with pulmonary venous obstruction

The American Journal of Cardiology (1994)

Jou‐Kou Wang Hung‐Chi Lue Ing‐Sh Chiu Mei‐Hwan Wu Chung‐I Chang

10.1016/0002-9149(94)90892-3

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Citations (2)

A Electrocardiographic Study of Normal Newborn Infants

Acta paediatrica sinica (1962)

Hung‐Chi Lue Chiung-Min Chen Chiung-Lin Chen

At birth a fundamental change in the circulation occurs. With the establishment of respiration the lungs expand, the pulmonary pressure falls, the blood in the left auricle increases, the pressure in the left auricle rises and the valve covering the foramen ovale tends to close, and the direction of the blood flow through the ductus arteriosus is reversed or virtually ceases1. Thus, in stead of one circulation-systemic, two circulations-systemic and pulmonary-are established. All these changes are reflected more or less in the electrocardiograms. It was in 1908, five years after Einthoven's invention of the string galvanometer, when Nicolai and Funaro published the first study of electrocardiograms in infants and children^2. The studies made hither-to-now disclose that the patterns of electrocardiogram vary progressively with age as with growth of the. infants and chi1dren.^3,4,5,6,7,8 Establishment of adequate standards of the normal, therefore, should be of fundamental importance before any attempt is made for diagnostic evaluation of the abnormal. Because there, was no such a study ever made in Taiwan, our purpose in undertaking this work is to find out the characteristic electrocardiographic patterns during the period of from birth to one week of life, and to establish criteria for the electrocardiograms of normal newborn in this particular period of life.

Ductus arteriosus

Foramen

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Citations (2)

Cryptococcal Me Ingitis : A Case Report

黃伯驥呂鴻基蕭柳青 Pai-Chi Hwang Hung‐Chi Lue

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Rapid diagnosis of streptococcal pharyngitis with enzyme immunoassay.

PubMed (1990)

Ju-Min Chu Jong‐Min Chen Mei‐Hwan Wu Jin‐Yang Hong Yingming Wang

From June 1988 to May 1989, 444 throat swab specimens were tested with an enzyme immunoassay kit for rapid diagnosis of group A streptococcal pharyngitis. The results were compared with those of throat culture method. The rapid test was positive in 37 of 42 culture-positive specimens and negative in 379 of 402 culture-negative specimens, thus yielding a total agreement of 93.7%, sensitivity 88.1%, specificity 94.7%, positive predictive value 61.7%, negative predictive value 98.7%. According to this practical application, we suggest that enzyme immunoassay test can be applied in outpatient clinics by busy pediatricians for rapid diagnosis of group A streptococcal pharyngitis.

Throat culture

Throat

Outpatient clinic

Group A

Positive predicative value

Microbiological culture

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PEDIATRIC EDUCATION FOR SPECIALISTS IN LESS-DEVELOPED-COUNTRIES - UNDERGRADUATE AND POSTGRADUATE TRAINING

Fernando José de Nóbrega C. A. Canosa V. C. Vaughan Hung‐Chi Lue

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