Yves Maury

Laboratoire Physiologie Cellulaire & Végétale

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Co-Authors

Marc Peschanski

Inserm

Cécile Martinat

Institut des Cellules Souches pour le Traitement et l'Étude des Maladies Monogéniques

R. K. Khetarpal

National Bureau of Plant Genetic Resources

Marina Bershteyn

Broad Center

Catherine Priest

Lineage Cell Therapeutics (United States)

Morgane Gauthier

Inserm

Cory R. Nicholas

University of California, San Francisco

Luis C. Fuentealba

University of California, San Francisco

G. Boudazin

Virologie et Immunologie Moléculaires

Alessandro Bulfone

Environment Park

Cooperative Institutions

Inserm

Centre National de la Recherche Scientifique

Institut des Cellules Souches pour le Traitement et l'Étude des Maladies Monogéniques

Institut National de la Recherche Agronomique

Université Paris-Saclay

University of California, San Francisco

Laboratoire Physiologie Cellulaire & Végétale

Université Paris Cité

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Université d'Évry Val-d'Essonne

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Introduction dans les plantes de genes derives de sequences du virus Y de la Pomme de terre

HAL (Le Centre pour la Communication Scientifique Directe) (1989)

Christophe Robaglia J. Masson Marie-Hélène Durand Tardif Yves Maury F. Casse‐Delbart

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Quality control of seed for viruses : present status and future prospects

Yves Maury R. K. Khetarpal

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Citations (1)

Non-invasive metabolic biomarkers of interneuron cell transplantation therapy in an epilepsy model

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2023)

Marina Radoul Kai Qiao Donghyun Hong Mansi Parekh Philip Hampel

Interneuron transplantation targeting GABAergic network dysfunction is a novel alternative therapeutic approach for chronic focal epilepsy. However, in vivo monitoring of response to such cellular therapeutics remains challenging. Here, we combined high resolution in vivo and ex vivo 1 H MRS to investigate the metabolic alterations in epileptic hippocampus in a preclinical model of chronic mesial temporal lobe epilepsy, and the effect of human inhibitory interneuron transplantation on metabolism. We discovered that hippocampal levels of GABA, NAA/Cr, GLX/Cr, GABA/GLX and GABA/NAA were reversed to healthy control levels in epileptic mice transplanted with inhibitory interneurons, providing unique biomarkers of therapeutic response.

Interneuron

Ex vivo

10.58530/2022/0590

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Isolation and properties of mesophyll cells of Chinese Cabbage (B. chinensis) infected with Turnip yellow mosaic virus.

Annales de Phytopathologie (1970)

J. Albouy Chantal Kusiak Hervé Lapierre F. Laquerrière Yves Maury

Turnip mosaic virus

Mosaic virus

Isolation

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Une observation inattendue dans la transmission du Pea Seed borne Mosaic Virus par la semence de Pois

HAL (Le Centre pour la Communication Scientifique Directe) (1990)

R.K. Khetarpal J.M. Bossennec Yves Maury

Mosaic

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A planned production experiment in an experimental herd.

Cl. Maire Yves Maury F. Poline

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Human pluripotent stem cells for disease modelling and drug screening

BioEssays (2011)

Yves Maury Morgane Gauthier Marc Peschanski Cécile Martinat

Abstract Considerable hope surrounds the use of disease‐specific pluripotent stem cells to generate models of human disease allowing exploration of pathological mechanisms and search for new treatments. Disease‐specific human embryonic stem cells were the first to provide a useful source for studying certain disease states. The recent demonstration that human somatic cells, derived from readily accessible tissue such as skin or blood, can be converted to embryonic‐like induced pluripotent stem cells (hiPSCs) has opened new perspectives for modelling and understanding a larger number of human pathologies. In this review, we examine the opportunities and challenges for the use of disease‐specific pluripotent stem cells in disease modelling and drug screening. Progress in these areas will substantially accelerate effective application of disease‐specific human pluripotent stem cells for drug screening.

Human disease

10.1002/bies.201100071

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Citations (58)

[Potato leafroll virus: purification, serologic detection and quantitative analysis in plants].

PubMed (1978)

M Mehrad Hervé Lapierre Yves Maury

The Potato Leafroll Virus has been purified from Potato. An antiserum obtained allows the use of the Enzyme Linked-Immunosorbent Assay, a direct means to detect the PLRV in the plant and to assess its real concentration.

Potato leafroll virus

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Embryonic stem cells neural differentiation qualifies the role of Wnt/β-Catenin signals in human telencephalic specification and regionalization

Stem Cells (2013)

Camille Nicoleau Christine Varela Caroline Bonnefond Yves Maury Aurore Bugi

Abstract Wnt-ligands are among key morphogens that mediate patterning of the anterior territories of the developing brain in mammals. We qualified the role of Wnt-signals in regional specification and subregional organization of the human telencephalon using human pluripotent stem cells (hPSCs). One step neural conversion of hPSCs using SMAD inhibitors leads to progenitors with a default rostral identity. It provides an ideal biological substrate for investigating the role of Wnt signaling in both anteroposterior and dorso-ventral processes. Challenging hPSC-neural derivatives with Wnt-antagonists, alone or combined with sonic hedgehog (Shh), we found that Wnt-inhibition promote both telencephalic specification and ventral patterning of telencephalic neural precursors in a dose-dependent manner. Using optimal Wnt-antagonist and Shh-agonist signals we produced human ventral-telencephalic precursors, committed to differentiation into striatal projection neurons both in vitro and in vivo after homotypic transplantation in quinolinate-lesioned rats. This study indicates that sequentially organized Wnt-signals play a key role in the development of human ventral telencephalic territories from which the striatum arise. In addition, the optimized production of hPSC-derived striatal cells described here offers a relevant biological resource for exploring and curing Huntington disease.

Ganglionic eminence

Neural Development

Directed differentiation

10.1002/stem.1462

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Citations (100)

[Isolation of the replicase of FH5 phage and its functioning in vitro at 2 different temperatures].

PubMed (1968)

Manifacier Sa P. Boistard P Cornuet J. Huppert H. Lapierre

Isolation

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