Gillian R. Naro

Penn State Milton S. Hershey Medical Center

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Timothy Craig

Pennsylvania State University

Ian R. Ross

Washington University in St. Louis

Rashmi Banjade

Penn State Milton S. Hershey Medical Center

Aparna Daley

Penn State Milton S. Hershey Medical Center

Jennifer B. Jacobs

Penn State Milton S. Hershey Medical Center

Rezhan Hussein

Penn State Milton S. Hershey Medical Center

Nicholas Noverati

Thomas Jefferson University Hospital

Cooperative Institutions

Penn State Milton S. Hershey Medical Center

Pennsylvania State University

Hershey (United States)

Washington University in St. Louis

John Cochran VA Medical Center

Crittenton Hospital Medical Center

Vinmec International Hospital

University of Leeds

Centre for the Observation and Modelling of Earthquakes, Volcanoes and Tectonics

University of California, San Diego

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

The Role of C1-Esterase Inhibitors in the Management of Vasogenic Edema in Glioblastoma

Case Reports in Medicine (2020)

Gillian R. Naro Nicholas Noverati Timothy Craig

Glioblastoma (GB) is one of the most common adult primary brain tumors, classified as a grade IV astrocytoma and highly malignant in nature. As the tumor grows and disrupts the blood-brain barrier (BBB), vasogenic edema can result. The edema has the potential to significantly contribute to a patient’s morbidity and mortality. Bradykinin has been theorized to play a role in this process as well as encourage tumor spread. Here we discuss a case in which a patient with vasogenic edema and angioedema refractory to antihistamines and high dose corticosteroids responded to C1-esterase inhibitor (C1INH) therapy. Though data exist concerning the role of bradykinin in GB, no clinical studies using C1INH have been done in humans with GB.

Brain Edema

Refractory (planetary science)

Brain tumor

10.1155/2020/7981609

Cite

Citations (6)

POPS case: A 30-year-old Filipino woman with fevers, lymphadenopathy, painful scalp lesions, and a neck mass

Allergy and Asthma Proceedings (2020)

Aparna Daley Gillian R. Naro Timothy Craig Rezhan Hussein Rashmi Banjade

We described a case of a 30-year-old Filipino woman who presented with fevers, night sweats, left hip pain, painful scalp lesions, and a neck mass. Symptoms began 6 months earlier, with nasal drainage, fever, cough, and occasional hemoptysis, which did not resolve with outpatient antibiotics. A further workup revealed lymphadenopathy and several lytic bone lesions. Her hospital course was later further complicated by the development of a tracheoesophageal fistula secondary to an esophageal mass and, then later, aseptic meningitis. Extensive diagnostic workup and immunologic tests were performed and finally led to the diagnosis. Here, we discussed the diagnostic workup and pathophysiology of the underlying condition. This case illustrated the importance of appropriate immunologic workup to make the diagnosis of a rare condition that proves to be clinically significant and presents challenges in management.

Tracheoesophageal Fistula

Neck mass

Neck pain

10.2500/aap.2020.41.200012

Cite

Citations (2)