Yuki Kawasaki

Children's Hospital of Michigan

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Takeshi Sasaki

Children's Hospital of Michigan

Yosuke Murakami

Osaka City General Hospital

Eiji Ehara

Osaka City General Hospital

Susumu Hijioka

National Cancer Center

Yoko Yoshida

Osaka City General Hospital

Tsugutoshi Suzuki

Osaka City General Hospital

Mitsuhiro Fujino

Osaka City General Hospital

Takuji Okusaka

Tokyo National Hospital

Yuta Maruki

National Cancer Center

Chigusa Morizane

National Cancer Center

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The University of Tokyo

117

Osaka University

Gifu University

Kyoto University

Tohoku University

Nagoya University

Osaka City General Hospital

National Cancer Center Hospital East

Tokyo Medical and Dental University

Gifu University Hospital

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中心に嚢胞成分を有するmixed acinar-neuroendocrine carcinomaの1例

Suizo (2021)

T Yuki Jun Ushio Atsushi Kanno Eriko Ikeda Kozue Ando

症例は57歳男性.検診で膵体部の嚢胞性病変が指摘され,当院を紹介された.造影CTでは膵体部に17mm大の中心部に嚢胞成分を伴う充実性腫瘤が認められた.3年後の造影CTでは,嚢胞成分を伴いながら23mm大に腫瘍径が増大し,MRIでは中心部の嚢胞成分はT1WI,T2WIともに高信号を示し,辺縁は拡散低下を伴う充実成分として観察された.超音波内視鏡検査でも同様に,中心に嚢胞成分を伴う充実性腫瘤として観察された.膵体尾部切除が施行され,病理学的にmixed acinar-neuroendocrine carcinoma(MAcNEC)と診断された.腫瘍中央の嚢胞成分は壊死によるものが疑われ,その周囲にsynaptophysin陽性の領域が,更にその周囲にBCL10,trypsin陽性の領域が分かれて確認された.本症例はMAcNECの発生様式を考察する上で示唆に富む症例であり,文献的考察を加え報告する.

Neuroendocrine carcinoma

Degeneration (medical)

10.2958/suizo.36.366

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Citations (1)

Genome-wide cytosine modification analysis by EnIGMA-seq.

The Molecular Biology Society of Japan (2016)

Yuki Kawasaki Yukiko Kuroda Fumitoshi Ishino Takashi Kohda

Cytosine

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Bark beetle outbreaks in Picea abies stands are associated with changes in wood-inhabiting fungal communities and seedling establishment on logs

Fungal ecology (2023)

Yu Fukasawa Václav Pouska Radek Bače Lucie Zíbarová Yuki Kawasaki

Microsite

10.1016/j.funeco.2023.101328

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Citations (1)

Corrigendum: Retrospective cohort study to determine the effect of preinjury antiplatelet or anticoagulant therapy on mortality in patients with major trauma

Frontiers in Medicine (2023)

Fuminori Yamaji Hideshi Okada Ryo Kamidani Yuki Kawasaki Genki Yoshimura

CORRECTION article Front. Med., 18 September 2023Sec. Intensive Care Medicine and Anesthesiology Volume 10 - 2023 | https://doi.org/10.3389/fmed.2023.1281829

Pain medicine

Anticoagulant Therapy

10.3389/fmed.2023.1281829

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An implication of the mitochondrial carrier SLC25A3 as an oxidative stress modulator in NAFLD

Experimental Cell Research (2023)

Takeo Nakanishi Yuki Kawasaki Yoshinobu Nakamura Yuuki Kimura Kotone Kawamura

Steatosis

Mitochondrial ROS

10.1016/j.yexcr.2023.113740

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Citations (5)

pH-dependent molecular weight changes of κ-casein glyco-macropeptide and its preparation by ultrafiltration

Milk science international/Milchwissenschaft (1993)

Yuki Kawasaki Hiroyuki Kawakami Morimasa Tanimoto Shun’ichi Dosako Akira Tomizawa

Ultrafiltration (renal)

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Citations (49)

The Diagnosis of Autoimmune Pancreatitis Using Endoscopic Ultrasonography

Diagnostics (2020)

Atsushi Kanno Eriko Ikeda Kozue Ando Hiroki Nagai Tetsuro Miwata

Autoimmune pancreatitis (AIP) is characterized by enlargement of the pancreas and irregular narrowing of the main pancreatic duct. It is often associated with IgG4-related sclerosing cholangitis (IgG4-SC), in which the bile duct narrows. Although characteristic irregular narrowing of the pancreatic duct caused by endoscopic retrograde cholangiopancreatography is noted in AIP, it is difficult to differentiate between localized AIP and pancreatic carcinoma based on imaging of the pancreatic duct. While stenosis of the bile duct in IgG4-SC is characterized by longer-length stenosis than in cholangiocarcinoma, differentiation based on bile duct imaging alone is challenging. Endoscopic ultrasound (EUS) can characterize hypoechoic enlargement of the pancreas or bile duct wall thickening in AIP and IgG4-SC, and diagnosis using elastography and contrast-enhanced EUS are being evaluated. The utility of EUS-guided fine needle aspiration for the histological diagnosis of AIP has been reported and is expected to improve diagnostic performance for AIP. Findings in the bile duct wall from endoscopic retrograde cholangiopancreatography followed by intraductal ultrasonography are useful in differentiating IgG4-SC from cholangiocarcinoma. Diagnoses based on endoscopic ultrasonography play a central role in the diagnosis of AIP.

Autoimmune Pancreatitis

Endoscopic Ultrasound

10.3390/diagnostics10121005

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Citations (11)

Valley index as a predictor of prenatal diagnosis of total anomalous pulmonary venous connection

Fetal Diagnosis and Therapy (2024)

Wakako Maruyama Yuki Kawasaki Yosuke Murakami Mitsuhiro Fujino Takeshi Sasaki

Total anomalous pulmonary venous connection (TAPVC) has a low prenatal diagnostic rate. Therefore, we investigated whether Doppler waveforms with a low pulsatility in the pulmonary veins can indicate fetal TAPVC.

Pulsatility index

Prenatal screening

10.1159/000539314

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Significance of neoadjuvant chemoradiotherapy for locally advanced pancreatic cancer

HPB (2018)

Hiroshi Kurahara K. Maemura Yulo Mataki Masahiko Sakoda S. Iino

Chemoradiotherapy

Radioresistance

Endoscopic Ultrasound

10.1016/j.hpb.2018.06.1951

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[The value of serum C-reactive protein as a survival determinant in patients with advanced non-small-cell lung cancer].

PubMed (2000)

Kazuhiro Kato Yutaka Hitsuda Yuki Kawasaki Tadashi Igishi K Yasuda

We retrospectively reviewed the information in our data base concerning 127 patients with advanced non-small-cell lung cancer. Seventeen pretreatment clinical variables including serum C-reactive protein (CRP) were analyzed to determine the factors related to survival using Cox's proportional hazards model. Univariate analysis revealed that eleven explanatory variables were significant. In multivariate statistical technique for those variables, six were selected as significant factors. The highest hazard ratio was observed in the serum CRP (3.82). The other factors were therapy (2.52), serum lactate dehydrogenase (2.41), serum total protein (2.20), white blood cell counts (1.98) and performance status (1.80). Median survival times estimated by the Kaplan-Meier procedures in patients with normal CRP (CRP < 0.2 mg/dl) and high positive CRP (CRP > or = 3.0 mg/dl) were 24.9 months and 3.7 months, respectively. These results suggest that serum CRP is an independent survival determinant in advanced non-small-cell lung cancer.

White blood cell

Univariate analysis

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Citations (9)