Guojie Lu

Panyu District Central Hospital

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Jiayin Wu

Shanghai Jiao Tong University

Haowei Wang

Shanghai Jiao Tong University

Hongze Wang

Shanghai Jiao Tong University

Yi Wu

Guangdong University of Technology

Huihui Yang

Shanghai Jiao Tong University

Qianglong Wei

State Key Laboratory of Metal Matrix Composites

Zengqiang Niu

Huazhong University of Science and Technology

Zijue Tang

Shanghai Jiao Tong University

Le Wan

Shanghai Jiao Tong University

Caiwang Tan

Harbin Institute of Technology

Cooperative Institutions

Shanghai Jiao Tong University

Huazhong University of Science and Technology

Sun Yat-sen University

Southern Medical University

State Key Laboratory of Metal Matrix Composites

Guangdong Provincial People's Hospital

Sichuan University

Chinese Academy of Sciences

Harbin Institute of Technology

Guangdong Academy of Medical Sciences

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A novel multi-information fusion CNN for defect detection in laser soldering of SAC305

Microelectronics Reliability (2024)

Wei Wang Hongyun Zhao Biao Yang Fuyun Liu Lianfeng Wei

10.1016/j.microrel.2024.115519

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An unresectable and metastatic intrahepatic cholangiocarcinoma with EML4-ALK rearrangement achieving partial response after first-line treatment with ensartinib: a case report

Frontiers in Oncology (2023)

Senmiao Huang Dianhe Li Yongye Huang Guojie Lu Ying Tian

Systemic chemotherapies are the primary treatment options for patients with unresectable and metastatic intrahepatic cholangiocarcinoma (ICC), but the effectiveness of current systemic therapies is limited. The development of targeted-therapy has changed the treatment landscape of ICC, and comprehensive genome sequencing of advanced cholangiocarcinoma patients could be beneficial to identify potential targets to guide individualized treatment. Herein, we reported an unresectable and metastatic ICC patient who detected EML4-ALK rearrangement in peripheral blood, which was later confirmed on tissue-based testing, and achieved partial response (PR) after first-line treatment with ensartinib. This case suggests that the liquid biopsy is of clinical value for unresectable or metastatic ICC, and the discovery of rare molecular targets provides new therapeutically approaches for advanced ICC patients.

Intrahepatic Cholangiocarcinoma

Targeted Therapy

Complete response

10.3389/fonc.2023.1191646

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Melt pool behavior of pure copper-stainless steel multi-materials fabricated by the coaxial hybrid blue-infrared lasers additive manufacturing

Journal of Manufacturing Processes (2024)

Wei Yang Yaling Wen Jingguang Du Yinqian Tian Heng Zhou

Coaxial

10.1016/j.jmapro.2024.07.049

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Citations (1)

Achieving crack-free CuCrZr/AlSi7Mg interface by infrared-blue hybrid laser cladding with low power infrared laser

Journal of Alloys and Compounds (2022)

Huihui Yang Zijue Tang Le Wan Qianglong Wei Jiayin Wu

Cladding (metalworking)

Power density

10.1016/j.jallcom.2022.167572

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Citations (29)

Stable cladding of high reflectivity pure copper on the aluminum alloy substrate by an infrared-blue hybrid laser

Additive Manufacturing Letters (2022)

Huihui Yang Jiayin Wu Qianglong Wei Zijue Tang An Wang

A coaxial infrared-blue hybrid laser system was adopted in the cladding of high reflectivity pure copper on an AlSi7Mg alloy substrate, and the cladding stability, molten pool size and microstructure of the cladded samples by three types of laser sources (infrared, blue and their hybrid sources) were compared. The infrared-blue hybrid laser was validated to compensate for the forming instability of a high-power infrared laser and a low-power density blue laser. In addition, the heat accumulation in the cladding process with the hybrid laser was more obvious and the cooling rate was slower (1.36 × 104 K/s), which led to a coarser microstructure (1.56∼2.42 μm). Therefore, the hybrid laser can bring about stability and a larger molten pool size in cladding pure copper on the aluminum substrate, which is closely related to the great increase in the total laser absorption rate of the high reflectivity alloy and the reduction in the fluctuation of the absorption rate.

Cladding (metalworking)

10.1016/j.addlet.2022.100040

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Citations (31)

Improving the efficiency of identifying malignant pulmonary nodules before surgery via a combination of artificial intelligence CT image recognition and serum autoantibodies

European Radiology (2022)

Yu Ding Jingyu Zhang Weitao Zhuang Zhen Gao Kaiming Kuang

Nomogram

Neuroradiology

Univariate

Univariate analysis

10.1007/s00330-022-09317-x

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Citations (9)

Vector control strategy for small-scale grid-connected PMSG wind turbine converter

Chunxue Wen Guojie Lu Peng Wang Zhengxi Li Xiong-Wei Liu

The purpose of this paper is to find an innovative, high efficiency, practical and low cost control system structure with an optimized control strategy for small-scale grid-connected wind turbine with direct-driven permanent magnet synchronous generator (PMSG). This research adopts the sensorless vector control strategy based on phase-locked loop (PLL) for PMSG control, and the grid-side inverter control strategy is based on the single-phase PLL. The simulation demonstrates that the sensorless control strategy and single-phase grid-side inverter control strategy are practical solutions for grid-connected PMSG wind turbines, and they can provide both generator speed control for optimized wind power tracking and good power quality control for electricity delivered to the grid. The designed system offers many unique advantages, including simple topology, optimized control strategy, cost-effective and fast respond to grid failures.

10.1109/isgteurope.2011.6162678

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Citations (14)

Achieving an improved formability and microstructure in infrared-blue laser hybrid cladding of pure Cu on AlSi7Mg substrate via infrared laser beam circular oscillating scanning

Optics & Laser Technology (2024)

Huihui Yang Qianglong Wei Jiayin Wu Zijue Tang Le Wan

Cladding (metalworking)

10.1016/j.optlastec.2024.110785

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Microstructure and molten pool morphology of TiB2/ AlSi7Mg composites fabricated by infrared-blue hybrid laser powder bed fusion

Heliyon (2024)

Jiayin Wu Huihui Yang Guojie Lu Yi Wu Hongze Wang

A hybrid laser composed of infrared and blue laser is applied in fabricating TiB2/AlSi7Mg composites on AlSi7Mg substrate by LPBF. The effect on formability, molten pool morphology, molten pool size and microstructure under infrared, blue and hybrid laser were compared. It was confirmed that hybrid laser can make up for the unbalanced energy distribution of infrared laser and the low energy density of blue laser. The increased energy input improves the molten pool size and cellular dendrites size. Therefore, the hybrid laser can improve the formability and forming stability in the LPBF process of low absorption rate alloys.

Morphology

10.1016/j.heliyon.2024.e25196

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Citations (1)

Microstructure and Molten Pool Morphology of Tib2/ Alsi7mg Composites Fabricated by Infrared-Blue Hybrid Laser Powder Bed Fusion

Jiayin Wu huihui Yang Guojie Lu Yi Wu Hongze Wang

A coaxial hybrid infrared-blue laser is applied in fabricating TiB2/ AlSi7Mg composites on AlSi7Mg substrate by LPBF. The effect on formability, molten pool morphology, molten pool size and microstructure under infrared, blue and hybrid laser were compared. It was confirmed that hybrid laser can make up for the unbalanced energy distribution of infrared laser and low energy density of blue laser. The increased energy input improves the molten pool size and cellular dendrites size. Therefore, hybrid laser can improve the formability and forming stability in LPBF process of low absorption rate alloys.

Morphology

10.2139/ssrn.4482228

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