Four Schiff-base copper(II) complexes, [Cu(L1)(Phen)(H2O)](NO3)2 (1), [Cu(L1)(bipy)(H2O)](ClO4)(H2O)(NO3) (2), [Cu(L1)(Dien)](ClO4)2(H2O) (3), and [Cu(L1)(ImH)(H2O)](ClO4) (4) (L1 = N-[(1)-pyridin-2-ylmethylidene]benzohydrazide, Phen = 1,10-phenanthroline, bipy = 2,2′-bipyridine, Dien = diethylenetriamine, ImH = imidazole), have been synthesized and characterized using various physico-chemical techniques. L1 is coordinated to copper(II) neutral and uninegatively charged tridentate chelating agent via the azomethine nitrogen, pyridine nitrogen, and carbonyl oxygen. The copper(II) complexes are paramagnetic with octahedral stereochemistry. The crystal structures of the complexes reveal the presence of structure consisting of a tridentate N, N, O donor Schiff base, tridentate NNN donor polyamine or N, N donor heterocyclic base and the copper(II) center. In 1, 2, and 4, water is present as a coordinating molecule whereas in 2 and 4 it is also present as lattice water. In discrete monomeric species all complexes show significant hydrogen-bonding interactions. H-bridges are also present in the solid state structure. Complexes 1–4 effectively catalyze the dismutation of superoxide () in alkaline nitro blue tetrazolium assay and IC50 values were determined. The susceptibility of certain strains of bacteria toward the precursors L1 and their complexes were also evaluated.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Abstract The pH-dependence of the EPR spectra of a newly synthesized imidazolate-bridged Cu(II)-Zn(II) complex, [(dien)Cu(im)Zn(dien)]3+ (dien = diethylenetriamine, im = imidazolate anion), has been studied in frozen solution (50% DMSO) to explore the mode of breaking of the imidazolate bridge. The data suggest that the imidazolate bridge in the complex is stable only at high pH (>9) and breaks on the zinc side at lower pH values.
'%3e%3ccircle r='20' fill='%23008'/%3e%3ccircle r='17.5' fill='%23fff'/%3e%3ccircle r='3.5' fill='%23008'/%3e%3cg id='d'%3e%3cg id='c'%3e%3cg id='b'%3e%3cg id='a' fill='%23008'%3e%3ccircle r='.875' transform='rotate(7.5 -8.75 133.5)'/%3e%3cpath d='M0 17.5.6 7 0 2l-.6 5L0 17.5z'/%3e%3c/g%3e%3cuse xlink:href='%23a' transform='rotate(15)'/%3e%3c/g%3e%3cuse xlink:href='%23b' transform='rotate(30)'/%3e%3c/g%3e%3cuse xlink:href='%23c' transform='rotate(60)'/%3e%3c/g%3e%3cuse xlink:href='%23d' transform='rotate(120)'/%3e%3cuse xlink:href='%23d' transform='rotate(-120)'/%3e%3c/g%3e%3c/svg%3e)
