Haicheng Yan

CRC for Rail Innovation

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Changwu Dou

Inner Mongolia Medical University

Songtao Qi

Southern Medical University

Wei Wang

Union Hospital

Youle Su

Inner Mongolia Medical University

Wuyun Su

Inner Mongolia Medical University

Fuming Tian

Inner Mongolia Medical University

Fu-Ming Tian

Inner Mongolia Medical University

Lian Shuang

Inner Mongolia Medical University

Fei Wang

Inner Mongolia Medical University

Youle Su

Inner Mongolia Medical University

Cooperative Institutions

Inner Mongolia Medical University

Southern Medical University

Inner Mongolia Medical College Hospital

Chinese Academy of Medical Sciences & Peking Union Medical College

Chongqing Medical University

Fujian Medical University

Nanfang Hospital

Sichuan University

Capital Medical University

Weifang People's Hospital

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

RETRACTED ARTICLE: Relationships of LDLR genetic polymorphisms with cerebral infarction: a meta-analysis

Molecular Biology Reports (2014)

Haicheng Yan Wei Wang Changwu Dou Fu-Ming Tian Songtao Qi

genetic model

10.1007/s11033-014-3313-4

Cite

Citations (5)

Association of LIG4 and XRCC4 gene polymorphisms with the risk of human glioma in a Chinese population.

PubMed (2015)

Youle Su Songtao Qi Changwu Dou Lian Shuang Haicheng Yan

We conducted a case-control study to assess the LIG4 and XRCC4 genes polymorphisms and development of glioma. A case-control study including 162 glioma cases and 324 controls was conducted in a Chinese population. Genotypes of rs10131 and rs1805388 in LIG4 and rs2075685 and rs1805377 in XRCC4 were conducted by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) assay. Conditional logistic regression analysis showed that subjects carrying AA genotype of LIG4 rs10131 was associated with increased risk of glioma when compared with GG genotype, and the OR (95% CI) was 3.26 (1.50-7.23). We found that GA+AA of LIG4 rs10131 was associated with increased risk of glioma in those without family history of cancer, and the OR (95% CI) was 1.78 (1.12-2.83). However, no association was found between variants of LIG4 rs1805388, XRCC4 rs2075685 and XRCC4 rs1805377 and development of glioma. In conclusion, our results suggest that LIG4 rs10131 polymorphism in the DNA repair pathways plays an important role in the risk of glioma in a Chinese population.

Source

Cite

Citations (12)