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10.1001/jamainternmed.2016.4544

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Citations (2)

Trichomonas Vaginalis Treatment Reduces Vaginal HIV-1 Shedding

Sexually Transmitted Diseases (2008)

Patricia Kissinger Angela M. Amedee Rebecca A. Clark Jeanne Dumestre Katherine P. Theall

Vaginal HIV-1 shedding has been associated with Trichomonas vaginalis (TV) infection and could play a role in HIV transmission. The purpose of the study was to examine if effective TV treatment reduces the presence of vaginal HIV-1 RNA.TV+ women attending an HIV outpatient clinic in New Orleans, LA, who resolved infection (n = 58) and TV-negative controls (n = 92), matched on antiretroviral therapy (ART) were examined and interviewed at baseline, 1, and 3 months. TV status was tested by culture and the amount of cell free HIV-1 RNA in the vaginal fluids was determined by the Amplicor HIV-1 Monitor ultrasensitive assay.: Most women (81.3%) were black and the mean age was 37.5 (SD 8.7). At baseline, 46.0% had plasma HIV-1 RNA >/=10,000 copies/mL, 26.4% had CD4<200 cells/muL, 54.7% were taking ART, and only 26.0% had detectable HIV-1 RNA in their vaginal fluids. TV-positive women who were effectively treated for TV were less likely to shed HIV vaginally at 3-months post-treatment compared to baseline (R.R. 0.34, 95% CI: 0.12-0.92, P = 0.03), whereas there was no change for TV-negative women.This study provides additional support that reducing TV infection among HIV-positive women may have an impact on the prevention of HIV transmission. Reasons for the delayed treatment effect and the effect on cervical shedding need further investigation.

Outpatient clinic

Vaginal discharge

Trichomonas Vaginitis

Trichomonas

Trichomoniasis

10.1097/olq.0b013e318186decf

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Citations (161)

Beer Consumption and Premature Mortality in Louisiana

Deborah Cohen Karen Mason Thomas A. Farley

Consumption

Source

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Citations (1)

Fourier transform Raman spectroscopy of illicit drugs

Journal of Raman Spectroscopy (1989)

Colin M. Hodges P.J. Hendra H.A. Willis Thomas A. Farley

Abstract Fourier transform (FT) Raman spectroscopy was investigated as a means of characterizing pure amphetamine sulphate, cocaine hydrochloride, heroin and diluted (‘cut’) samples of these drugs at drug concentrations down to 5%. The pure compounds give spectra that are excellent for rapid identification, as do samples cut with sorbitol. Some cutting agents are fluorescent, however, and identification then presents difficulties. The major advantage of FT Raman spectroscopy over other techniques for the testing of illicit drugs is that no sample preparation is needed. The test is very fast (3 min), and after examination the sample can be completely recovered in the same form as that in which it was received, so that it can, if required, be submitted to other test procedures.

Drug Detection

Hydrochloride

Sample Preparation

10.1002/jrs.1250201108

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Citations (49)

Half-Life ofTh232and the Branching Ratio ofBi212

Physical Review (1956)

F.E. Senftle Thomas A. Farley N. H. Lazar

The half-life of ${\mathrm{Th}}^{232}$ has been calculated by determining an absolute gamma-disintegration rate for ${\mathrm{Tl}}^{208}$ in equilibrium with ${\mathrm{Th}}^{232}$ for three old thorium nitrate salts and one natural thorite sample. The branching ratio, $\frac{\ensuremath{\alpha}}{(\ensuremath{\alpha}+\ensuremath{\beta})}$, for ${\mathrm{Bi}}^{212}$, a necessary parameter in the calculation, was also measured. The half-life of ${\mathrm{Th}}^{232}$ was found to be 1.42\ifmmode\times\else\texttimes\fi{}${10}^{10}$ years within an estimated error of 5%, which is essentially in agreement with the presently accepted value. The branching ratio, $\frac{\ensuremath{\alpha}}{(\ensuremath{\alpha}+\ensuremath{\beta})}$, of ${\mathrm{Bi}}^{212}$ was found to be 0.362\ifmmode\pm\else\textpm\fi{}0.006, about 7.4% higher than the currently accepted value.

Branching fraction

10.1103/physrev.104.1629

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Citations (41)

The Impact of Influenza Vaccination on Respiratory Illness at a Boarding School

Journal of American College Health (1992)

Thomas A. Farley J.-M. Germain Linda A. Chamberlain Leonard S. Krassner

We studied the impact of influenza vaccine during an outbreak of influenza at a 989-student boarding school in January to March, 1989. By February 6, 120 (17%) of 690 students completing survey questionnaires had been ill with fever and respiratory symptoms. Eighty-seven students had received influenza vaccine in the previous 18 months; these students had an attack rate half that of the unvaccinated students (9% v 19%; vaccine efficacy = 50%, confidence interval = 0%-70%). We estimate that, if the entire student body had been vaccinated, influenza-like illness could have been prevented in 162 students (16% of the school), and that preventing this illness could have avoided at least 482 student-days of missed classes, or approximately one student-day for each 1.8 additional doses of vaccine given. This study suggests that, when feasible, a broad influenza immunization policy for healthy students at residential schools should substantially decrease the disruption of school activities caused by influenza.

Respiratory illness

Pandemic

10.1080/07448481.1992.9936312

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Citations (12)

Where Do the Children Play? The Influence of Playground Equipment on Physical Activity of Children in Free Play

Journal of Physical Activity and Health (2008)

Thomas A. Farley Rebecca A. Meriwether Erin T. Baker Janet C. Rice Larry S. Webber

Background: Promotion of physical activity in children depends on an understanding of how children use play equipment. Methods: We conducted observations over 2 years of children in 2nd through 8th grades in a schoolyard with 5 distinct play areas with different amounts of play equipment. Results: Children were more likely to play in areas with more installed play equipment, with densities of children in equipped areas 3.3 to 12.6 times higher than in an open grassy field. There were no significant differences by play area in the percent of children who were physically active at all, but children were more likely to be very active in areas with basketball goals and an installed play structure than in an open field. Conclusions: Playground equipment appeared to have a strong influence on where children played and a moderate influence on levels of activity. To maximize physical activity in children, playgrounds should be designed with ample and diverse play equipment.

Promotion (chess)

Basketball

10.1123/jpah.5.2.319

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Citations (89)

Measuring the Food Environment: Shelf Space of Fruits, Vegetables, and Snack Foods in Stores

Journal of Urban Health (2009)

Thomas A. Farley Janet C. Rice J. Nicholas Bodor Deborah A. Cohen Ricky N. Bluthenthal

Healthy food

Snack food

10.1007/s11524-009-9390-3

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