Abstract Our aim is to reveal the interaction of cultural and religious influences with professional equipment by determining the level of knowledge, sexual attitudes, and homophobia of medical students about LGBTI+ individuals. The study included 324 students from our faculty of medicine. The Hudson and Ricketts Homophobia scale, the Attitudes Towards Lesbians and Gay Men scale, and the Hendrick Sexual Attitudes scale were used with the sociodemograpic data form. Data were collected and analyzed using descriptive and inferential statistical tests. The mean score of the students from the Hudson and Ricketts Homophobia scale was 58.50. The findings of our study support that medical students consider that the education they receive in this regard is inadequate. One of the goals of undergraduate medical education is the provision of health services to all segments of society; therefore, it is recommended to make improvements in the curriculum in this regard.
Abstract Purpose The number of studies conducted on the role of neuroinflammation in the etiopathogenesis of bipolar disorder has been increasing in recent years. The role of Galectin‐1, Galectin‐9, and YKL‐40, which are considered to play roles in neuroinflammation and the etiopathogenesis of bipolar disorder, and the relationship of these parameters with cognitive functions were investigated in the present study. Method Serum Galectin‐1, Galectin‐9, and YKL‐40 levels were measured with the ELISA Method in 64 bipolar euthymic patients and 64 healthy controls. The Stroop and trail‐making tests were administered to assess cognitive functions in all participants. Results Serum Galectin‐1, Galectin‐9, and YKL‐40 levels were statistically and significantly lower in the patient group when compared to the healthy control group. The scores of the Stroop test and trail‐making tests were statistically higher in the patient group than in the healthy control group. There was a weak and positive correlation between serum Galectin‐1, Galectin‐9, and YKL‐40 levels and cognitive performance in all participants. Discussion and conclusion Statistically significant low levels of serum Galectin‐1, Galectin‐9, and YKL‐40 detected in the patient group suggest that these parameters have important roles in neuroinflammation. The statistically higher Stroop and trail‐making test scores of the patient group compared to the control group indicates that the cognitive performance of the patient group was weaker. Also, the positive correlation between Galectin‐1, Galectin‐9, and YKL‐40 levels and cognitive performance suggests that these molecules may have a neuroprotective role. We think that the present study will contribute to this field where there is very limited data in the literature.
Objective:
ECT is still an important treatment modality in contemporary psychiatry. Despite the evidence regarding its efficacy and safety, patients are hesitant about ECT, which is sometimes stigmatized due to disinformation. Today, YouTube, an online media platform, is mostly used as a medical information source. This study investigated the quality and reliability of electroconvulsive therapy videos available on YouTube.
Methods:
A video search on YouTube (http://www.youtube.com) was conducted on 20 October 2020, using the keywords electroconvulsive therapy schizophrenia, electroconvulsive therapy depression, and electroconvulsive therapy psychiatric disorders in this descriptive study. After applying the exclusion criteria, a total of 79 videos were included in this study. The Global Quality Scale (GQS) was used to assess educational quality and the modified DISCERN tool was used to assess reliability. Video parameters (the numbers of views, likes, dislikes, and comments for per day) were compared among the low/medium/high quality groups.
Results:
45.2% (n: 42) of the videos were of low quality, 25.8% (n: 24) were of medium quality and 14% (n: 13) were of high quality. High-quality videos were 38.5% from psychiatrists, 23.1% from academic resources, 23.1% from health-related websites. Modified DISCERN scores were higher in the high quality video group (p
Purpose: The aim of this study was to determine the relationship between childhood trauma and aggression-suicidal behavior in patients with bipolar disorder.Material and Methods: A total of 112 outpatients diagnosed with bipolar disorder in remission in the province of Siirt on the east coast of Turkey were included in this study carried out between January and June 2018. Personal Information Form, Childhood Trauma Questionnaire (CTQ), Buss–Perry Aggression Scale (BPAS) and Suicide Probability Scale (SPS) were used for data acquisition.Results: It was determined that patients with bipolar disorder have 89.3% of physical neglect, 74.1% of emotional neglect, 75.9% of physical abuse, 79.5% of emotional abuse and 40.2% of sexual abuse. The mean score of CTQ was 66.8 ± 19.2, the total score of BPAS was 94.6 ± 28.8 and the total score of SPS was 85.3 ± 17.9. A statistically significant and positive correlation was determined between CTQ, BPAS and SPS (p < 0.05).There was a weak and positive relationship between BPAS, CTQ (r = 0.325**; p < 0.05) and subscales of CTQ which are emotional abuse (r = 0.350**; p < 0.05), physical abuse (r = 0.354**; p < 0.01), physical neglect (r = 0.313**; p < 0.01) and emotional neglect (r = 0.316**; p < 0.01). A statistically significant difference was observed between the regular use of drugs, violence against others and total score of CTQ, BPAS and SPS (p < 0.05).Conclusion: It is suggested that patients diagnosed with bipolar disorder should be evaluated with regards to childhood trauma history by taking into consideration sociodemographic characteristics and psychiatric support in order to prevent their aggression and suicide attempts.
Non-adherence to treatment and hospital admissions are the common problems in severe mental disorders. To determine the contribution of community mental health center (CMHC) services to increased hospitalization rates of patients previously diagnosed with severe mental disorders such as schizophrenia spectrum and other psychotic disorders and bipolar disorders. 356 patients diagnosed with bipolar disorder, schizophrenia, schizoaffective disorder, and unspecified schizophrenia spectrum and other psychotic disorders in accordance with the DSM–5 criteria and treated in the CMHC on the south coast of Turkey were included in this retrospective study.The hospitalization records of the patients were examined over three different periods. First and second period: two divided years which patients had not yet received CMHC services before registration. Third period: one-year, during which patients using CMHC services. A total of 356 patients were included in the study. SPSS 22.0 (IBM Corporation, Armonk, New York, United States) software was used in the analysis of variables. Normal distribution of data was assessed with the Shapiro–Wilk test. The diagnosis of the participants in the study were 157 (44%) schizophrenia, 35 (9.8%) schizoaffective disorder, 102 (28.7%) bipolar disorder and 62 (17.4%) unspecified schizophrenia spectrum and other psychotic disorders. As a result of the hospitalization rates, there was a significant difference between three periods. The median number of hospitalization days during the first episod was calculated as 1.0 (mean 13.9), the second period 0.7 (mean 18.59) and third period 0.6 (mean 5.83), respectively.The rate of hospitalization was 32.9% in the first period, 42.4% in the second period and 12.9% in the third period. This study provides the new evidence regarding the ability of primary services offered in the community mental health centers.
Amaç: Bu çalışmada obsesif kompulsif bozukluk (OKB) hastalarında ürik asit, albümin, total bilirubin ve gamma glutamil transferaz (GGT) gibi serumda ölçülebilen oksidatif stres ile ilişkili basit laboratuvar parametrelerini sağlıklı kontroller ile karşılaştırılması amaçlanmıştır.
Gereç ve Yöntem: Çalışmaya Gaziantep Üniversitesi Tıp Fakültesi Hastanesi Psikiyatri polikliniğinde DSM-5 kriterlerine göre OKB tanısı ile tedavi edilen hastalar alınmıştır. OKB tanısı konulan 117 hasta ve hasta grubu ile demografik veriler ile eşleşebilecek 80 kişi sağlıklı kontrol grubu olarak alındı. Hasta ve kontrol grubu serum ürik asit, albümin, total bilirubin ve GGT açısından karşılaştırıldı. Hastaların klinik özellikleri Yale Brown Obsesyon Kompulsiyon Ölçeği (Y-BOCS) ve Klinik Global İzlenim Şiddet Ölçeği (KGI-S) ile değerlendirildi.
Bulgular: Hasta grubu yaş ortalaması 36.68±13.06 iken kontrol grubunun 35.54±8.82’di. Total bilirubin düzeyine bakıldığında hasta grubunda 0.69±2.19 mg/dL ve kontrol grubunda 0.63±0.47 mg/dL olmakla birlikte gruplar arasında anlamlı farklılık vardı. GGT düzeyi hasta grubunda 22.85±15.80 U/L ve kontrol grubunda ise 19.29±11.52 U/L olmakla birlikte gruplar arasında anlamlı fark yoktu.
Sonuç: Hastalar bilirubin dışında doğal antioksidan açısından kontrollerden farklı değildi. Çalışmamızdaki bulgular OKB ile ürik asit, albümin ve GGT arasında nedensel bir ilişki olduğunu desteklememektedir.
Objective: Suicide is the most common cause of premature death of schizophrenia. This study investigated the relationship between cholesterol levels and suicidal behaviour in chronic psychosis. Methods: The study group consisted of 109 schizophrenia, schizoaffective and other non affectice psychosis defined by Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-V) criteria. Lifetime suicide attempts of patients were retrospectively screened. The patients were divided into two groups with and without suicide. Serum cholesterol levels were compared between two groups. Results: The mean total cholesterol, triglyceride, HDL and LDL levels were 163.8 mg/dl,150.8 mg/dl,40.8 mg/dl and 132.4 mg/dl, respectively in the study group while they were 197.1 mg/dl, 194 mg/dl, 44.9 mg/dl and 124.2 mg/dl, respectively in the control group. Total cholesterol levels were significantly lower than patients with suicidal attempts compared with the patients with no suicidal attemps (p=0,03). No association was found between suicidal attempt and HDL cholesterol (p=0,24), triglyceride (p=0,193), and LDL(p=0,45). Conclusion: This result supports the hypothesis of association low plasma cholesterol levels and suicidal behavior in psychosis
Amaç: Elektrokonvulsif terapinin (EKT) majör depresyonda etkinliği bilinmektedir. Bu çalışmada majör depresyonda EKT’nin total antioksidan seviye, total oksidan seviye, oksidatif stres indeksi üzerindeki etkilerine bakılmıştır. Gereç ve Yöntem: DSM-IV’e göre majör depresyon tanısı konulan 23 hasta ve 22 sağlıklı kontrol çalışmaya alındı. Hastalara sosyodemografik ve klinik bilgilendirme formu uygulandı. Hasta ve kontrollerden venöz kan örnekleri alındı. serum total antioksidan, total oksidan düzeylerine bakıldı. Bulgular: Elektrokonvulzif terapi uygulaması öncesi hasta grubunda antioksidan seviye kontrol grubuna kıyasla daha düşük bulunmuştur. Hasta grubunda EKT uygulaması sonrası antioksidan seviye elektrokonvulzif terapi öncesine göre anlamlı düzeyde artmıştır. Elektrokonvulzif terapi uygulaması sonrası antioksidan seviye kontrol grubu ile kıyaslandığında anlamlı farklılık kalmamıştır. EKT öncesi ve sonrasında bakılan total oksidan seviye ve oksidatif stres indeksi açısından hasta ve kontrol grupları arasında anlamlı farklılık saptanmamıştır. Sonuç: EKT uygulaması sonrasında hastalarda total antioksidan seviye düzeyinin artması, EKT’nin majör depresyon hastalarında antioksidan seviye artışına neden olduğunu düşündürmektedir.
Although catatonia has been previously associated with schizophrenia, today it is more associated with mood disorders and general medical conditions. Periodic catatonia is a rare type of catatonic syndrome having frequently and constantly repeated catatonic episodes. In the pathogenesis of catatonia several mechanisms have been suggested. Benzodiazepines and electroconvulsive therapy (ECT) have been used as first line treatment in catatonia. We report about the case of a patient successfully treated with maintenance ECT in periodic catatonia.