Oya F

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Clinical evaluation of antibody sensitized latex particles method for Australia antigen in serum.

PubMed (1974)

Oya T Oya F K Tomimura

There are several testing methods for the detection of Australia antigen. Among them an antibody sensitized latex particle agglutination assay (LAT) for the detection is technologically simple, sensitive, and rapid. So the detection of the antigen in the 896 specimens from hepatic diseases was carried out by LAT. IEOP. and SRID and the detection of rheumatoid factor in the LAT positives was also made by the modified method of Heller et al. The results of testing the 896 specimens from blood donors are positive in 0.8%. negative in 4.1%. false positive in 5.1%. and false negative in 0.1%. And also. it is suggested that false positive to LAT is partially due to rheumatoid factor. since 7 specimens of 9 positives for rheumatoid factor were to LAT (a rate of 67.8%). and partially due to the freshness of blood, since of 59 storage specimens at 4°C for a week there were different reactions in 21 specimens between storage specimens and fresh specimens. Two false negatives in the 61 specimens from hepatic diseases showed positive reactions in diluted specimens for LAT. The cause of false negative reactions to LAT is unclear but it may partly be due to the rheumatoid factor and other factors. These results led us to the conclusions that the LAT requires further development and that the LAT appears to be useful as a preliminary screening for detection of the antigen.

Latex fixation test

Rheumatoid factor

Agglutination (biology)

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Serum lipoprotein estimation by polyacrylamide gel disc electrophoresis.

PubMed (1974)

Oya F Oya T Kyoko Toda

A simple, rapid method is described for separating the serum lipoproteins into clear, discrete and reproducible bands by polyacrylamide disc gel electro phoresis. The sample is prestained with Sudan Black B in a sample gel and resolved by electrophoresis in a discontinuous pH system consisting of a sample gel, concentrating gel and separating gel. 30 young healthy males and 20 young healthy females were examined with the method. The examination of 22 young people of them showed trace amount of chylomicrons. No significant sex difference could be demonstrated in the plasma concentrations of chylomicrons, {3. and pre· f3. and a·lipoproteins as a whole.

Chylomicron

Plasma lipoprotein

Polyacrylamide

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[Giant cell tumor originating in the sphenoid bone: a case report].

PubMed (1999)

Yukinari Kakizawa Yuu Tanaka Hideki TAKASAWA Oya F Takuhito Tada

The authors report a case of giant cell tumor originating in the sphenoid bone. A 29-year-old woman presented with headache and diplopia. Bilateral ophthalmoplegia developed and MRI showed rapid growth of the tumor in spite of transnasal removal and conventional radiation therapy. The second transnasal surgery was performed 3 weeks after completion of radiotherapy. The symptoms were relieved except for right abducens palsy. Chemotherapy with cisplatin and etoposide was started after the second operation. The patient regained full ocular movement several months after the operation. Clinical remission has continued for four years. We conclude that the combination of repeated operations in the initial phase of rapid tumor growth, irradiation and chemotherapy is important to achieve tumor control.

Abducens nerve

Sphenoid bone

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A case of gastric cancer with liver metastasis showing a positive serologic test for 1 -fetoglobulin.

PubMed (1971)

Oya F Haruhiko Makino Hanako Kuhara

Liver Cancer

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