Tuğba Kınay

Sağlık Bilimleri Üniversitesi

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Fulya Kayıkçıoğlu

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

Yaprak Engin Üstün

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

ÖM

Özlem Moraloğlu Tekın

Ankara Bilkent City Hospital

ÖL

Ömer Lütfi Tapısız

Güven Hospital

Funda Akpınar

Sağlık Bilimleri Üniversitesi

ŞA

Şule Atalay Mert

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

Seval Yılmaz Ergani

Memorial Ankara Hospital

Berna Dilbaz

Sağlık Bilimleri Üniversitesi

ŞK

Şadıman Kiykaç Altinbaş

Zübeyde Hanim Maternity Hospital

Jale Karakaya

Hacettepe University

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Zübeyde Hanim Maternity Hospital

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi

University of Health Sciences

University of Health Science

Ministry of Health

Memorial Ankara Hospital

Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi

Women’s Health Care

Başkent University

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Periüretral Apseye Neden Olan Üretral Divertikülit Olgusunun Tanı Ve Minimal İnvaziv Tedavisi

Türk Kadın Sağlığı ve Neonatoloji Dergisi (2019)

Sefanur Karaca Tuğba Kınay Ali Rıza Doğan Tufan Çiçek Şadıman Kiykaç Altinbaş

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Prevalence of endometrial polyps coexisting with uterine fibroids and associated factors

Journal of Turkish Society of Obstetric and Gynecology (2016)

Tuğba Kınay Zehra Öztürk Başarır Serap Fırtına Tuncer Funda Akpınar Fulya Kayıkçıoğlu

Amaç: Çalışmanın amacı uterin fibroid olgularında bulunan endometrial polip prevalansını ve bu iki patolojinin birlikteliği ile ilişkili faktörleri araştırmaktı

Endometrial Polyp

Uterine Fibroids

Endometrial hyperplasia

10.4274/tjod.36043

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Percentage change in body mass index or gestational weight gain: Which is a better predictor of foetal macrosomia?

Journal of Obstetrics and Gynaecology (2015)

İnci Kahyaoğlu Tuğba Kınay Fulya Kayıkçıoğlu Serkan Kahyaoğlu Leyla Mollamahmutoğlu

The aim of the study was to evaluate gestational weight gain (GWG) and percentage change in body mass index (BMI) for prediction of foetal macrosomia. A total of 409 term pregnant women, of whom 86 delivered macrosomic infants (> 4000 g) and 323 delivered non-macrosomic infants were recruited for the study. GWG and body mass index at delivery were significantly higher in the macrosomic than non-macrosomic group (15.8 ± 5.6 vs 13.9 ± 5.6, and 31.4 ± 4.3 vs 29.5 ± 4.3, respectively) (p < 0.05). The receiver operating characteristic curve analysis for testing the significance of weight gain in prediction of macrosomia showed an area under curve of 0.58 (p = 0.012, 95% confidence interval [CI] = 0.52-0.65), and significance of percentage change in BMI in prediction of macrosomia revealed an area under curve of 0.52 (p = 0.51, 95% CI = 0.46-0.59). BMI percentage changes both in obese (BMI ≥ 25) and non-obese (BMI < 25) groups were not statistically significant (p > 0.05). BMI percentage change does not seem to be a strong predictor of foetal macrosomia, and GWG was not found to be an independent risk factor after multivariate regression analysis was performed.

Fetal macrosomia

Mass index

10.3109/01443615.2015.1019435

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Histopathological Findings of Cystic Endometrial Morphology Based on Ultrasonographic Imaging in Premenopausal Women

Gynecology Obstetrics and Reproductive Medicine (2018)

Tuğba Kınay Metin Kaplan Fulya Kayıkçıoğlu Jale Karakaya

Objective: To evaluate the histopathological findings of cystic endometrial morphology based on ultrasonographic imaging in premenopausal women.Study Design: The medical records of 3607 premenopausal women that underwent ultrasonographic examination at a tertiary care center were reviewed, as were endometrial biopsy findings in 816 of the women. These 816 women were divided in 2 groups according to ultrasonographic endometrial findings: the cystic group and the non-cystic group. Clinical and histopathological findings in the 2 groups were compared. Statistical analysis was performed using independent samples t test, chi-square test, and binary logistic regression analysis.Results: Three hundred and eighty one (46.7%) of the women that underwent endometrial biopsy had cystic endometrium, whereas 435 (53.3%) had non-cystic endometrium. The most common histopathological finding in the cystic group was endometrial hyperplasia without atypia (44.6%). Cystic morphology was nearly 8-fold more common in the women with endometrial hyperplasia without atypia (95% CI: 5.43-11.67). The premalignant and malignant pathology rates in the cystic group and non-cystic group were similar (1.1% vs. 0.5% [p=0.426] and 0.8% vs. 0.5% [p=0.669], respectively). Secretory endometrium was less common in the cystic group than in the non-cystic group (5.0% vs. 37.9% [p< 0.001])Conclusion: Cystic endometrial morphology based on ultrasonographic imaging was more common in women with endometrial hyperplasia without atypia. There wasn’t an association between cystic endometrium and other endometrial pathologies or functional endometrium. Keywords: Cystic endometrium, Endometrium, Endometrial hyperplasia, Premenopausal, Ultrasonography

Atypia

Endometrial hyperplasia

Endometrial biopsy

Atypical Hyperplasia

10.21613/gorm.2018.773

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Results of fetal anomaly screening performed at 11–14 weeks of gestation at a tertiary center

Perinatal Journal (2016)

Tuğba Kınay Metin Kaplan Mehmet Metin Altay Şafak Özdemirci Sinan Karadeniz

Center (category theory)

Tertiary care

10.2399/prn.16.0242010

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Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience

Gynecology Obstetrics and Reproductive Medicine (2021)

Gulnihal Reyhan Toptas Eylem Ünlübilgin Tuğba Kınay Rıza Doğan Mehmet Akif Akgül

OBJECTIVE: The objective of this study was to determine the incidence of perioperative “severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)” infection among women, operated during Coronavirus disease-2019 (COVID-19) era. STUDY DESIGN: All patients who were operated on between March 11, 2020, and December 31, 2020, in our gynecology clinic were included in this cross-sectional study. The clinical and demographic characteristics of the patients, preoperative and postoperative SARS-CoV-2 positivity, the progress of the infection, and the survival rates in positive cases were analyzed. COVID-19 cases were diagnosed by reverse transcription-polymerase chain reaction testing for SARS-CoV-2. RESULTS: Operations of 133 (33%) of 406 patients were canceled for various reasons. 275 patients were operated on. Preoperatively three patients were diagnosed with COVID-19. One of these patients died and two were operated on after treatment and self-isolation. Only one (0.4%) patient was diagnosed with COVID-19 30 days postoperatively and completely recovered. We calculated the perioperative SARS-CoV-2 positivity rate as 1.4% (276 surgeries were planned and 4 patients were diagnosed with COVID-19). During the study, 107 physicians worked in our clinic alternately. Two (1.8%) of these physicians were diagnosed with COVID-19 and completely recovered without the need for intensive care. In addition, nine patients who were previously diagnosed with COVID-19 were operated on. Postoperative respiratory and other system complications did not occur in nine patients, previously diagnosed with COVID-19. CONCLUSION: The results of our study show that gynecological surgical procedures do not increase the transmission and mortality rates of SARS-CoV-2 among patients and healthcare professionals as long as infection control measures are followed.

Isolation

10.21613/gorm.2021.1206

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Do the change in β-hCG values between the 0th and 4th days in tubal ectopic pregnancy treatment with a single-dose methotrexate (MTX) protocol predict the need for a second dose of MTX?

Archives of Gynecology and Obstetrics (2023)

Yıldız Akdaş Reis Arife Akay Merve Özkan Fahri Burçin Fıratlıgil Murat Levent Dereli

Regimen

10.1007/s00404-023-07116-3

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The Predictive Value of Systemic Inflammation Markers for the Success of Labor Induction with Foley Catheter

Türk Kadın Sağlığı ve Neonatoloji Dergisi (2022)

Tuğba Kınay Şule Atalay Mert Caner Köse Sinan Karadeniz Yaprak Engin Üstün

Amaç: Sistemik inflamasyon belirteçlerinin foley kateter ile doğum indüksiyonu başarısını öngörmedeki değerini araştırmak. Gereç ve Yöntem: Retrospektif kohort çalışmaya foley kateter ile doğum indüksiyonu uygulanan ≥ 37 hafta, tek, canlı, verteks geliş olan düşük riskli gebeler dahil edildi. Doğum indüksiyonu sonrası sezaryen ile doğumun gerçekleşmesi indüksiyon başarısızlığı olarak kabul edildi. Çalışma popülasyonu doğum indüksiyonu sonrası vajinal doğum yapanlar ve sezaryen doğum yapanlar olarak iki gruba ayrıldı. İki grubun demografik ve klinik özellikleri, prepartum tam kan sayımı değerleri, nötrofil/lenfosit oranı ve platelet/lenfosit oranı karşılaştırıldı. Bulgular: Çalışmaya toplam 308 gebe dahil edildi. Olguların 159’unda (%51,6) doğum indüksiyonu sonrası vajinal yolla doğum gerçekleşirken, 149’unda (%48,4) sezaryen doğum ile gebelik sonlandı. Nulliparite oranı sezaryen ile doğum yapan olgularda (%68,5) vajinal yolla doğum yapanlara (%54,1) göre daha yüksek bulundu (p=0,01). Vajinal yolla doğum yapan ve sezaryen doğum gereksinimi olan olguların lökosit sayıları (9804,9 ± 3283,4 h/mm3’e karşı 10437,1 ± 4439,8 h/mm3), nötrofil/lenfosit oranı (4,7 ± 4,1’e karşı 4,4 ± 3,9) ve trombosit/lenfosit (149,3 ± 67,0’e karşı 139,3 ± 50,1) oranı arasında istatistiksel olarak anlamlı bir fark saptanmadı (p>0,05). Sonuç: Doğum indüksiyonu öncesi bakılan sistemik inflamasyon belirteçleri ile doğum indüksiyon başarısı arasında anlamlı ilişki bulunmadı. Bununla birlikte nulliparitenin foley kateter ile doğum indüksiyon başarısızlığı için bir risk faktörü olduğu saptandı.

Foley catheter

10.46969/ezh.1096673

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Incidence and outcome of occult uterine sarcoma: A multi-centre, retrospective study of 18604 operations performed for presumed uterine leiomyoma

Mehmet Mutlu Meydanlı AYÇAĞ YORGANCI Nezaket Kadıoğlu Salih Taşkın Fulya Kayıkçıoğlu

Occult

Uterine sarcoma

Uterine Leiomyoma

10.26226/morressier.5d43ffa5baa7e4c58300ab6d

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ANTENATAL EĞİTİMİN NULLİPAR KADINLARDA MATERNAL VE PERİNATAL SONUÇLAR ÜZERİNE ETKİSİ Effects of Antenatal Education on Maternal and Perinatal Outcomes in Nulliparous Women

Bozok Tıp Dergisi (2019)

Mustafa Bakırcı Fulya Kayıkçıoğlu Tuğba Kınay Özlem Moraloğlu Tekın

OZET Amac: Ev yerine hastanede yapilan dogumlarin bir sonucu olarak, kadinlari dogum icin hazirlamak amaciyla antenatal egitim programlari gelistirilmistir. Antenatal egitimin gebelik sonuclari ve dogum sureci uzerindeki etkisi henuz net degildir. Sunulan calismanin amaci, antenatal egitimin nullipar kadinlarda maternal ve perinatal sonuclari etkileyip etkilemedigini degerlendirmektir. Gerec ve Yontemler: Retrospektif vaka kontrol calismasinda, Ocak 2010-Aralik 2016 tarihleri arasinda ucuncu basamak bir merkezde dogum yapan 513 dusuk riskli nullipar kadinin tibbi kayitlari incelendi. Antenatal egitim alan 85 kadin calisma grubuna, egitim programina katilmayan 428 kadin kontrol grubuna dahil edildi. Gruplarin demografik ve klinik ozellikleri ile maternal ve perinatal sonuclari karsilastirildi. Bulgular: Antenatal egitim alan kadinlarin kontrol grubuna gore ortalama yasi (26.0 ± 4.4 vs. 23.5 ± 4.4; p <0.001) dusuk oykusu orani (5.9% vs. 0%; p<0.001) daha yuksek; sezaryen dogum orani ise (% 11.8 ve% 25.5, p 0.006) daha dusuktu. Gruplarin sezaryen endikasyonlari, dogum evrelerinin suresi, vajinal dogum yapan kadinlarda epizyotomi oranlari, postpartum komplikasyon oranlari ve perinatal sonuclari ise benzerdi. Sonuc: Antenatal egitim dusuk sezaryen dogum oranlari ile iliskili bulundu. Antenatal egitimin diger maternal ve perinatal sonuclar uzerine etkisi ise saptanmadi. Anahtar kelimeler: Antenatal egitim; Sezaryen seksiyo; Vaginal dogum; Nulliparite; Maternal sonuc; Perinatal sonuc ABSTRACT Aim: As a result of births in hospital instead of homes, antenatal education programs have been developed with the aim of preparing women for birth. The effect of antenatal education on pregnancy outcomes and birth process has not yet been fully clarified. The aim of the presented study was to evaluate whether antenatal education affects the maternal and perinatal outcomes in nulliparous women. Material and Methods: In this retrospective case-control study, medical records of 513 low-risk nulliparous women who gave birth between January 2010 and December 2016 at a tertiary care centre were reviewed. 85 women with antenatal education were included in the case group and 428 women who did not participate in the education program were included in the control group. The demographic, clinical characteristics, maternal and perinatal outcomes of groups were compared. Results: Mean age of women (26.0±4.4 vs. 23.5±4.4; p<0.001), history of abortion rate (5.9% vs. 0%; p<0.001) were higher and caesarean section rate (11.8% vs. 25.5%, p 0.006) was lower in women with antenatal education than in the control group. Caesarean indications, length of labour stages, episiotomy rates of women with vaginal delivery, postpartum complication rates, and perinatal outcomes of groups were similar. Conclusion: Antenatal education was associated with lower caesarean birth rates. There was no effect of antenatal education on the other maternal and perinatal outcomes. Keywords: Antenatal education; Caesarean section; Vaginal birth; nulliparity; Maternal outcome; Perinatal outcome

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