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Susan G. Marantz

Respiratory Health Association

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Supriya Jasuja

Cook County Department of Public Health

Baby M. Djojonegoro

University of Houston

Anna Lee

Chinese University of Hong Kong

Elizabeth Fair

University of California, San Francisco

Dolly Katz

Centers for Disease Control and Prevention

C. Robert Horsburgh

Boston University

Christine Ho

Centers for Disease Control and Prevention

Lauren A. Lambert

Centers for Disease Control and Prevention

Pei-Jean Feng

Centers for Disease Control and Prevention

Raymond MacDonald

University of Edinburgh

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Centers for Disease Control and Prevention

National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention

National Center for Immunization and Respiratory Diseases

Rutgers, The State University of New Jersey

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Cook County Department of Public Health

Chicago Department of Public Health

Florida Department of Health

Illinois Department of Public Health

Florida College

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LATENT TUBERCULOSIS INFECTION SCREENING OF FOREIGN BORN PATIENTS USING QUANTIFERON-GOLD (QFT-G) IN SUBURBAN COOK COUNTY TB CLINICS IN ILLINOIS

CHEST Journal (2007)

Supriya Jasuja Anna Lee Raymond MacDonald Susan G. Marantz

QuantiFERON

Skin test

Gold standard (test)

Tuberculin test

10.1378/chest.132.4_meetingabstracts.433

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Impact of Choice of Test for Latent Tuberculosis Infection on Treatment Acceptance and Completion

Microbiology Insights (2018)

Lauren A. Lambert Dolly Katz Pei-Jean Feng Baby M. Djojonegoro Elizabeth Fair

The aim of this study is to assess whether choice of test for tuberculosis (TB) infection affects decisions to accept and complete treatment among contacts to TB cases.Retrospective study is conducted in which TB contacts, ⩾15 years old during 2005 and 2009, were tested for infection with either a tuberculin skin test (TST) or an interferon-gamma release assay test, the QuantiFERON-TB Gold In-Tube (QFT-GIT).Of 658 persons with valid test results, 185 (28%) had positive results, including 128 of 406 (32%) who had TST and 57 of 252 (23%) who received QFT-GIT. Treatment acceptance was 43 of 57 (75%) among QFT-GIT-positive and 97 of 128 (76%) among TST-positive persons (risk ratio [RR] = 1.0, 95% confidence interval [CI], 0.83-1.2). Treatment completion was 56% among QFT-GIT-positive (32 of 57) and 59% (75 of 128) among TST-positive persons (RR = 0.96, 95% CI, 0.73-1.26).Our study showed no difference in proportions of TB contacts ⩾15 years old with positive TST results who accepted or completed LTBI treatment compared with those with positive QFT-GIT results. Future studies should include high-risk persons with no known TB exposure, who constitute the main reservoir for TB cases in the United States.

Skin test

QuantiFERON

10.1177/1178636118811311

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Citations (2)