Objective To evaluate if self-limited episodes of atrial fibrillation after direct current(DC) cardioversion predict re- currence of persistent atrial fibrillation. Methods Consecutive patients with persistent atrial fibrillation, scheduled for DC cardiover- sion were prospectively included in the study. Ambulatory ECG Hoher monitoring (24 h) was performed one, three and 6 weeks after successful cardioversion. Results A total of 80 patients were prospectively included in the study. Sinus rhythm was restored in 73 pa- tients (88%). At 6 weeks of follow -up 40 patients out of 73 (54%) had sinus thythm, and 33 patients (46%) had relapsed into per- sistent atrial frbrillation. Eight out of these 34 patients (24%) had bursts of atrial fibrillation at their first Holter recording, compared to 12 patients out of 40 (30%) in sinus rhythm at 6 weeks (P > 0.05). On the first, second and third Holter recording 21 patients out of 51 (41%), 22 patients out of 43 (51%) and 15 out of 40 patients (38%) had self - limited bursts of atrial fibrillation,respeetively. Condusion In patients successfully converted to sinus rhythm self- limited bursts of atrial fibrillation do not predict recurrence of persistent atrial fibrillation during 6 weeks of follow up. Brief self- limited episodes of atrial fibrillation are common, and the incidence and duration of such episodes are constant during a 6 weeks period after DC cardioversion.
Key words:
Arrhythmia; Atrial fibrillation; Cardioversion
This study uses the finite element software Midas GTS NX (2019), combined with actual engineering projects, to establish numerical models and analyze the impact of different support types (pile-anchor support and double-row pile support) on the excavation of foundation pits near metro station tunnels. The results indicate that under both support methods, the vertical displacement of the tunnel is the greatest at the interface between the station and the tunnel, with greater vertical displacement occurring under double-row pile support. Under pile-anchor support, the horizontal displacement of the tunnel reaches its maximum value during the sixth excavation stage, while under double-row pile support, the horizontal displacement increases steadily, and the overall displacement is small. The horizontal displacement under pile-anchor support is significantly greater than that under double-row pile support. For the station, the maximum vertical displacement under pile-anchor support is smaller than that under double-row pile support. The horizontal displacement under pile-anchor support exhibits a linear change, while under double-row pile support, the displacement continuously increases from the end of the foundation pit farther from the excavation to the end closer to it. The model tests are consistent with the numerical simulation results, verifying the correctness of the numerical simulation. This study can provide references for relevant engineering projects to ensure the safety and stability of metro structures.
Radikalisch nicht homopolymerisierbare Donator- und Akzeptormonomere lassen sich miteinander co-, ter- und quaterpolymerisieren. Die dabei entstehenden Polymeren sind immer alternierend aus 50 mol-% Donator- und 50 mol-% Akzeptormonomereinheiten aufgebaut. Kinetische Untersuchungen zeigen die gleichzeitige Beteiligung von freien Monomeren und den zwischen Donator- und Akzeptormonomeren gebildeten CT-Komplexen. Bei niedrigen Monomerkonzentrationen dominiert der Mecha-nismus mit freien Monomeren, bei hohen Monomerkonzentrationen werden die Komplexe wegen ihren hoheren Reaktivitat gegenuber den freien Monomeren bevorzugt ins Polymere einge-baut, was zu einer groseren Polymerisationsgeschwindigkeit fuhrt. Tetrahydrofuran, Chloroform und Acetonitril zeigen deutliche Losungsmitteleffekte sowohl fur die Beteiligungen von freien Monomeren und von Komplexen als auch fur die Zusammensetzungen der resultierenden Polymeren, weil Komplexbildungskonstante von den Losungsmitteln abhangig ist.
Abstract In this paper, the mechanical properties (compression and impact behaviours) of three-dimension structure (3D-structure) composites based on warp-knitted spacer fabrics have been thoroughly investigated. In order to discuss the effect of fabric structural parameters on the mechanical performance of composites, six different types of warp-knitted spacer fabrics having different structural parameters (such as outer layer structure, diameter of spacer yarn, spacer yarn inclination angle and thickness) were involved for comparison study. The 3D-structure composites were fabricated based on a flexible polyurethane foam. The produced composites were characterised for compression and impact properties. The findings obtained indicate that the fabric structural parameters have strong influence on the compression and impact responses of 3D-structure composites. Additionally, the impact test carried out on the 3D-structure composites shows that the impact loads do not affect the integrity of composite structure. All the results reveal that the product exhibits promising mechanical performance and its service life can be sustained.
Microtubule‑associated protein 1 light chain 3 (LC3) is an autophagy‑associated gene, which is involved in the progression of a number of human malignancies. Such as Breast Cancer, Liver Cancer, and Lung Cancer. However, the role of LC3 in colorectal cancer (CC) remains to be fully elucidated. Therefore, the prognostic role of LC3 expression in CC was evaluated in the present study, with an emphasis on the clinicopathology and prognosis. Expression of LC3 in CC was examined using PubMed, Cochrane Library, Excerpta Medica Database, China Knowledge Infrastructure and Wanfang Data. Newcastle‑Ottawa scale was used to screen the literature quality, and RevMan 5.4 and STATA 14.0 were used for the meta‑analysis. A total of 1,689 patients from 10 studies were included in the present meta‑analysis. The findings of the present study suggested that increased LC3 expression levels were associated with histological grade [odds ratio (OR)=0.91, 95% confidence interval (CI) (0.47, 1.77), P<0.001] and TNM stage [OR=0.91, 95% CI (0.47, 1.77), P<0.001], but were not associated with sex [OR=1.14, 95% CI (0.90, 1.51)], age [OR=0.89, 95% CI (0.67, 1.20)], tumor size [OR=0.78, 95% CI (0.30, 2.34)], histological grade [OR=0.82, 95% CI (0.43, 1.95)] and lymph node metastasis [OR=2.05, 95% CI (1.19, 3.60)] in CC. In addition, the increased expression of LC3 was revealed to be a prognostic factor for the overall survival of patients with CC. In conclusion, the autophagy‑associated protein LC3 may be a prognostic indicator of human CC.
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