Katherine J. Karriker‐Jaffe

RTI International

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Thomas K. Greenfield

Alcohol Research Group

Nina Mulia

Alcohol Research Group

William C. Kerr

Alcohol Research Group

Sarah E. Zemore

Alcohol Research Group

Amy A. Mericle

Alcohol Research Group

D.J. Patterson

Alcohol Research Group

Meenakshi S. Subbaraman

Public Health Institute

Won Kim Cook

Alcohol Research Group

Susan T. Ennett

University of North Carolina at Chapel Hill

Yu Ye

Public Health Institute

Cooperative Institutions

Alcohol Research Group

Public Health Institute

RTI International

University of California, Berkeley

University of California, San Francisco

University of Washington

University of Michigan–Ann Arbor

Virginia Commonwealth University

University of California, Los Angeles

University of North Carolina at Chapel Hill

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Differential Consequences: Racial/Ethnic and Gender Differences in the Enduring Impact of Early Disadvantage on Heavy Drinking in Midlife

Prevention Science (2019)

Katherine J. Karriker‐Jaffe Jane Witbrodt Nina Mulia

Disadvantage

Educational Attainment

Health psychology

Longitudinal Study

Life course approach

10.1007/s11121-019-01033-1

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Citations (3)

Impact of the policy environment on substance use among sexual minority women

Drug and Alcohol Dependence Reports (2022)

Laurie A. Drabble Cat Munroe Amy A. Mericle Sarah Zollweg Karen F. Trocki

Sexual minority women (SMW) are at greater risk for heavy episodic drinking, frequent marijuana use, and tobacco use than heterosexual women. Because past research has suggested the political and social environment may influence disparities in substance use by sexual orientation, this study examined associations of the U.S. state-level policy environment on substance use by SMW.A total of 732 SMW participants were recruited from two national online panels: a general population panel (n = 333) and a sexual minority-specific panel (n = 399). Past year substance use was defined by number of days of heavy episodic drinking (HED; 4+ drinks in a day), weekly tobacco use (once a week or more vs. less or none), and weekly marijuana use (once a week or more vs. less or none). Comprehensive state policy protection was defined by enactment of five policies protecting rights of sexual minorities. Regression models compared substance use outcomes for SMW living in states with comprehensive policy protections to SMW living in states with fewer or no protections. Models also assessed the impact of state policies related to alcohol (state monopoly on alcohol wholesale or retail sales), tobacco (state enactment of comprehensive smoke-free workplace laws) and marijuana (legalization of purchase, possession, or consumption of marijuana for recreational use).Comprehensive policy protections were associated with fewer HED days. Recreational marijuana legalization was associated with higher odds of weekly use.Findings underscore the importance of policy protections for sexual minorities in reducing substance use, particularly HED, among SMW.

Legalization

10.1016/j.dadr.2022.100058

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Citations (6)

Time-specific and cumulative effects of exposure to parental externalizing behavior on risk for young adult alcohol use disorder

Addictive Behaviors (2017)

Alexis C. Edwards Sara Larsson Lönn Katherine J. Karriker‐Jaffe Jan Sundquist Kenneth S. Kendler

Alcohol use disorder

10.1016/j.addbeh.2017.03.002

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Citations (14)

Modeling the impact of a long‐term horizon and multiple treatment episodes on estimates of the cost‐effectiveness of alcohol treatment in the United States

Alcohol Clinical and Experimental Research (2023)

Carolina Barbosa William N. Dowd Katherine J. Karriker‐Jaffe Gary A. Zarkin

Abstract Background Most clinical studies of alcohol use disorder (AUD) treatment have short follow‐up periods, underestimating the full benefits of alcohol treatment. Furthermore, clinical studies only consider one treatment cycle and do not account for the need for multiple episodes to treat a chronic recurrent condition. Methods A validated microsimulation model of the long‐term drinking patterns of people with AUD in the United States simulated 10,000 individuals resembling those from a large clinical trial. The model was used to assess the impact of (1) 1‐year, 5‐year, and lifetime horizon on alcohol treatment cost‐effectiveness estimates and (2) no, one, two, four, and unlimited additional treatment episodes on alcohol treatment cost‐effectiveness estimates. Model outcomes included healthcare costs, crime costs, labor market productivity, life expectancy, quality‐adjusted life years (QALYs), alcohol‐related hospitalizations, and deaths. Cost‐effectiveness analyses were conducted for two perspectives: a healthcare perspective that included costs from hospitalization and AUD treatment, and a broader societal perspective that also included crime costs and productivity. Results The incremental cost per additional QALY gained for alcohol treatment compared with no treatment decreased from $55,590 after 1 year to $78 when healthcare costs and QALYs were tracked over the lifetime, that is, treatment became more cost effective. Treatment was cost saving for any time frame when the impacts on crime and labor productivity were also accounted for in a societal perspective. Access to multiple treatment episodes dominated (i.e., it was more effective and less costly) than no‐treatment and one‐episode scenarios. From a healthcare perspective, incremental costs per additional QALY for increasing from a maximum of two to four treatment episodes was $499 and from four to unlimited episodes was $5049. The unlimited treatment scenario dominated all others from a societal perspective. Results were robust in sensitivity analyses. Conclusions A long‐term perspective and multiple episodes of alcohol treatment improve cost‐effectiveness estimates. When societal impacts are included, alcohol treatment is cost saving. Results support the value of alcohol treatment.

Time horizon

10.1111/acer.15186

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Citations (2)

Neighborhood Context Measure

PsycTESTS Dataset (2007)

Vangie A. Foshee Susan T. Ennett Karl E. Bauman Douglas A. Granger Thad Benefield

10.1037/t16136-000

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Citations (0)

Receipt of Medications for Alcohol and Opioid Use Disorders: The Importance of Service Utilization Patterns

The Journal of Behavioral Health Services & Research (2024)

Kara M. Bensley Katherine J. Karriker‐Jaffe Joanne Delk Libo Li Yu Ye

Receipt

Alcohol use disorder

10.1007/s11414-024-09918-y

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Citations (0)

Review: Environmental influences on alcohol use: Informing research on the joint effects of genes and the environment in diverse U.S. populations

American Journal on Addictions (2017)

Karen G. Chartier Katherine J. Karriker‐Jaffe Cory Cummings Kenneth S. Kendler

Background and Objectives This review aimed to inform the current state of alcohol research on the joint effects of genes and the environment conducted in U.S. racial/ethnic minority populations, focusing on African Americans, Latinos/Hispanics, Asians, and American Indians. Methods A key‐word and author‐based search was conducted and supplemented with direct contact to researchers in this area to ensure a comprehensive inclusion of published, peer‐reviewed studies. These studies were considered in terms of the racial/ethnic population groups, phenotypes, genetic variants, and environmental influences covered. Research findings from alcohol epidemiologic studies were highlighted to introduce some potential environmental variables for future studies of gene and environment (G–E) relationships. Results Twenty‐six ( N = 26) studies were reviewed. They predominantly involved African American and Asian samples and had a very limited focus on Latinos/Hispanics and American Indians. There was a wide range of alcohol‐related phenotypes examined, and studies almost exclusively used a candidate gene approach. Environmental influences focused on the most proximate social network relationships with family and peers. There was far less examination of community‐ and societal‐level environmental influences on drinking. Epidemiologic studies informing the selection of potential environmental factors at these higher order levels suggest inclusion of indicators of drinking norms, alcohol availability, socioeconomic disadvantage, and unfair treatment. Conclusions The review of current literature identified a critical gap in the study of environments: There is the need to study exposures at community and societal levels. Scientific Significance These initial studies provide an important foundation for evolving the dialogue and generating other investigations of G–E relationships in diverse racial/ethnic groups. (Am J Addict 2017;26:446–460)

Disadvantage

10.1111/ajad.12478

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Citations (36)

Alcohol- and Drug-Related Mortality Among Adults Within and Outside the U.S.–Mexico Border Region

Journal of Studies on Alcohol and Drugs (2022)

Sarah E. Zemore Libo Li Kara M. Bensley Katherine J. Karriker‐Jaffe Cheryl J. Cherpitel

Objective: Although researchers and policy makers have often considered the U.S.–Mexico border region to be at high risk for substance use problems, epidemiological studies of this region have been hard to interpret because of their modest geographic coverage, reliance on self-report, and mixed results. The current study addresses limitations of existing studies and extends the knowledge base by comparing alcohol- and drug-related mortality in counties on versus off the border across all four U.S. border states. Method: Data were from the 2008–2017 Centers for Disease Control and Prevention WONDER Multiple Causes of Death data set, American Community Survey, and Rural Urban Continuum Codes, including all four border states. Spatial lag models tested differences across on- and off-border counties in total alcohol- and drug-related mortality (“total mortality”), alcohol-related mortality, and drug-related mortality. Results: In multivariate models, mortality rates were significantly higher in off- versus on-border counties for all three outcomes (ps < .05). Rates for total mortality, alcohol-related mortality, and drug-related mortality were 28%, 82%, and 30% higher, respectively, off versus on the border. Border effects were similar, excluding California; robust over time; and stronger for Latinx versus White decedents. Conclusions: Results suggest a revised understanding of the border, revealing that residents of interior counties of border states are at highest risk of severe substance use consequences. Results are consistent with other research finding that border counties were protected against drug overdose deaths, particularly for Latinx residents.

10.15288/jsad.2022.83.175

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Citations (4)

Neighborhood Disadvantage and Adult Alcohol Outcomes: Differential Risk by Race and Gender

Journal of Studies on Alcohol and Drugs (2012)

Katherine J. Karriker‐Jaffe Sarah E. Zemore Nina Mulia Rhonda Jones‐Webb Jason Bond

We examined whether relationships of neighborhood disadvantage with drinker status, heavy drinking, alcohol-related consequences, and dependence differed by race and/or gender. We hypothesized that neighborhood disadvantage would be negatively associated with drinker status but positively associated with heavy and problem drinking, with more pronounced relationships among African American and Hispanic men than other groups.Data consisted of nationally representative, randomly selected, cross-sectional samples of White, African American, and Hispanic adults (N = 13,864, of which 52% were female; with 7,493 drinkers, of which 48% were female) from the 2000 and 2005 National Alcohol Surveys merged with 2000 Census data. Analyses included logistic and linear regression using weights to adjust for sampling and nonresponse.Hypotheses were partly supported. Bivariate relationships were in the expected direction. Multivariate main effect models showed that neighborhood disadvantage was significantly associated with increased abstinence and marginally associated with increased negative consequences experienced by drinkers, but race/ethnicity and gender modified these associations. Disadvantage was significantly associated with increased abstinence for all groups except African American and Hispanic men. Among drinkers, disadvantage was significantly negatively associated with heavy drinking by Whites but significantly positively associated with heavy drinking by African Americans. Disadvantage also was associated with elevated alcohol-related consequences for White women and African American men.The findings have implications for the development of targeted interventions to reduce the unequal impacts of neighborhood disadvantage on alcohol outcomes. Future research should examine the contribution of multiple types of disadvantage to heavy drinking and alcohol problems.

Disadvantage

Heavy drinking

10.15288/jsad.2012.73.865

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Citations (98)

To drive or not to drive? A study of travel behavior for a recent drinking occasion

Travel Behaviour and Society (2020)

Kara E. MacLeod Mikkel Thorhauge Víctor Villalobos Jeroen van Meijgaard Katherine J. Karriker‐Jaffe

Mode choice

Taxis

Binge drinking

Consumption

Risk Perception

Affect

10.1016/j.tbs.2020.02.008

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Citations (7)