S S Daniel

Instituto Nacional de Pediatria

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Gerardo Barragán Mejía

Instituto Nacional de Pediatria

Hugo Juárez Olguı́n

Universidad Nacional Autónoma de México

David Calderón Guzmán

Instituto Nacional de Pediatria

Ernestina Hernández García

Universidad Nacional Autónoma de México

Norma Osnaya Brizuela

Instituto Nacional de Pediatria

L. Stanley James

Cork University Hospital

Norma Labra Ruíz

Instituto Nacional de Pediatria

Romana Stark

Australian Regenerative Medicine Institute

Ivonne Espitia-Vázquez

Instituto Nacional de Pediatria

Francisca Trujillo Jiménez

Universidad Nacional Autónoma de México

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Instituto Nacional de Pediatria

Columbia University

Universidad Nacional Autónoma de México

Instituto Nacional de Neurología y Neurocirugía

The University of Texas Health Science Center at Houston

The University of Texas Health Science Center at San Antonio

Columbia University Irving Medical Center

Universidad Autónoma Metropolitana

NewYork–Presbyterian Hospital

Harvard University

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EFFECTS OF POSITIVE PRESSURE VENTILATION OF THE MOTHER UPON THE ACID-BASE STATE OF THE FETUS

Survey of Anesthesiology (1966)

Hisayo O. Morishima S S Daniel Karlis Adamsons L. Stanley James Gertie F. Marx

MORISHIMA, H. O.; DANIEL, S. S.; ADAMSONS, K. JR.; JAMES, L. S.; MARX, GERTIE F. M.D. Author Information

Base (topology)

Positive pressure ventilation

10.1097/00132586-196608000-00037

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Citations (1)

Assessment of mexican arnica (Heterotheca inuloides Cass) and rosemary (Rosmarinus officinalis) extracts on dopamine and selected biomarkers of oxidative stress in stomach and brain of Salmonella typhimurium infected rats

Pharmacognosy Magazine (2017)

David Calderón Guzmán Maribel Ortíz Herrera Norma Osnaya Brizuela Gerardo Barragán Mejía Ernestina Hernández García

Pharmacognosy Magazine ,2017,13,50,203-208.DOI:10.4103/0973-1296.204553Published:April 2017Type:Original Article Authors:David Calderón Guzmàn, Maribel Ortiz Herrera, Norma Osnaya Brizuela, Gerardo Barragàn Mejía, Ernestina Hernàndez García, Hugo Juàrez Olguín, Armando Valenzuela Peraza, Norma Labra Ruíz, and Daniel Santamaría Del Angel Author(s) affiliations:David Calderón Guzmàn, Maribel Ortiz Herrera1 , Norma Osnaya Brizuela, Gerardo Barragàn Mejía, Ernestina Hernàndez García2 , Hugo Juàrez Olguín2 , Armando Valenzuela Peraza, Norma Labra Ruíz, Daniel Santamaría Del Angel Laboratorio de Neurociencias, Instituto Nacional de Pediatría (INP), Mexico City 1Laboratorio de Bacteriología Experimental, INP, SSA, Mexico City 2Laboratorio de Farmacología, INP, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico Abstract:Background: The effects of some natural products on dopamine (DA) and 5-hydroxyindole acetic acid (5-HIAA) in brain of infected models are still unclear. Objective: The purpose of this study was to measure the effect of Mexican arnica/rosemary (MAR) water extract and oseltamivir on both biogenic amines and some oxidative biomarkers in the brain and stomach of young rats under infection condition. Methods: Female Wistar rats (weight 80 g) in the presence of MAR or absence (no-MAR) were treated as follows: group 1, buffer solution (controls); oseltamivir (100 mg/kg), group 2; culture of Salmonella typhimurium (S. Typh) (1 × 106 colony-forming units/ rat) group 3; oseltamivir (100 mg/kg) + S. Typh (same dose) group 4. Drug and extracts were administered intraperitoneally every 24 h for 5 days, and S.Typh was given orally on days 1 and 3. On the fifth day, blood was collected to measure glucose and hemoglobin. The brains and stomachs were obtained to measure levels of DA, 5-HIAA, glutathione (GSH), TBARS, H2 O2 , and total ATPase activity using validated methods. Results: DA levels increased in MAR group treated with oseltamivir alone but decreased in no-MAR group treated with oseltamivir plus S. Typh. 5-HIAA, GSH, and H2 O2 decreased in this last group, and ATPase activity increased in MAR group treated with oseltamivir plus S. Typh. TBARS (lipid peroxidation) increased in MAR group that received oseltamivir alone. Most of the biomarkers were not altered significantly in the stomach. Conclusion: MAR extract alters DA and metabolism of 5-HIAA in the brain of young animals infected. Antioxidant capacity may be involved in these effects. Keywords:5-HIAA, DA, Glutathione, Mexican rosemary plant, Mexican arnica plant, Salmonella typhimuriumView:PDF (570.19 KB)

Rosmarinus

10.4103/0973-1296.204553

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Citations (2)

Effect of valproic acid on levels of GABA and glutamic acid in pentylenetetrazole-damaged rat brain.

PubMed (2003)

Calderón Guzmán D Ivonne Espitia-Vázquez Gerardo Barragán Mejía Labra Ruiz N Rodríguez Pérez R

Valproic Acid

Glutamic acid

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Citations (6)

Response of Ovine Uterine Blood Flow to Angiotensin II

Obstetric Anesthesia Digest (1982)

Samuel L. Bruce Hisayo O. Morishima Roy H. Petrie Kaori Sakuma S S Daniel

Bruce, S. L.; Morishima, H. O.; Petrie, R. H.; Sakuma, K.; Daniel, S. S.; Yeh, S. -Y.; Johnson, Robert W. F.F.A.R.C.S. Author Information

10.1097/00132582-198203000-00008

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Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate

Andrologia (2011)

David Calderón Guzmán Eugene Bratoeff E. Ramírez López Ernestina Hernández García Francisco Pierdant Rioja

Flutamide is a steroid used to treat androgen-dependent disorders and as antiepileptic, but it induces a number of non-desirable side effects. This work was aimed at assaying the effect of flutamide and two novel synthetic steroids on the levels of GABA, glutamine and oxidative stress markers. Male Wistar rats (weight 180 g) received a single diazepam dose (5 mg/kg) 30 min prior to sacrifice (group A). Group B, flutamide; group C, 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione; group D, estrone-3-hemisuccinate; group E, testosterone; group F, progesterone; all administered intraperitoneally at 10 mg/kg, daily for 3 days. Brain and prostate were obtained to assess lipid peroxidation (TBARS), Na(+) , K(+) ATPase activity, reduced glutathione (GSH), γ-amino butiric acid (GABA), glutamine and serotonin (5-HT) concentrations through spectrophotometry, fluorescence and HPLC. GABA levels increased and glutamine decreased in group A (P < 0.05). Total ATPase activity increased in group F and TBARS decreased in group B (P < 0.05). GSH decreased in A, B and C groups. 5-HT increased in group A and the prostate weight was increased in group E. The conclusion is that 16β-methyl-17α-benzoyloxypregnen-4-en-3,20-dione may be considered novel and promising to treat androgen-dependent diseases and epilepsy, since it showed an antioxidant effect and seemed to impair the GABAergic and serotonergic metabolism.

Flutamide

TBARS

10.1111/j.1439-0272.2010.01051.x

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Citations (2)

Effects of terbutaline on the pregnant baboon and fetus.

PubMed (1977)

Steve N. Caritis H O Morishima Romana Stark S S Daniel L. Stanley James

The effects of terbutaline on the mother and fetus were evaluated in 8 near-term pregnant baboons. Significant suppression of postoperative spontaneous and oxytocin-augmented uterine activity was achieved with infusion rates of 0.36 and 0.56 microgram/kg/min, respectively. Maternal and fetal blood pressure and acid-base states as well as fetal heart rate were unaffected by the administration of terbutaline to the mother, but a mild maternal tachycardia was observed. Both maternal and fetal blood glucose increased during terbutaline infusion. Direct administration of terbutaline to the fetus did not alter the fetal cardiovascular or acid-base state. It is concluded that in the baboon, terbutaline is an effective tocolytic agent with minimal untoward effects on either mother or fetus.

Terbutaline

Tocolytic

Tocolytic agent

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Citations (17)

Hypothermia and the resuscitation of asphyxiated fetal rhesus monkeys

The Journal of Pediatrics (1966)

S S Daniel G. S. Dawes L. Stanley James Bernhard Roß William F. Windle

Neonatal Resuscitation

10.1016/s0022-3476(66)80421-3

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Citations (39)

Assessment of Oxidative Damage Induced by Acute Doses of Morphine Sulfate in Postnatal and Adult Rat Brain

Neurochemical Research (2006)

David Calderón Guzmán Ivonne Espitia-Vázquez Norma Osnaya Brizuela Raquel García-Álvarez Gerardo Barragán Mejía

10.1007/s11064-006-9053-7

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Citations (61)

Effect of nutritional status and ozone exposure on Na+/K+ ATPpase and lipid peroxidation in rat brain.

PubMed (2005)

David Calderón Guzmá José Luis Hernández Islas Gerardo Barragán Mejía S S Daniel Ernestina Hernández García

The aim of this study was to analyze the effect of nutritional status and exposure to ozone on the activity of Na+/K+ ATPase and lipid peroxidation in rat brain. Male Wistar rats were fed 7% and 23% protein diets. Two groups were formed for each nutritional status: one group was exposed for 15 successive days to 0.75 ppm of ozone in air and the other was exposed to air. Subsequently, the brain was dissected and cortex, hemispheres, cerebellum and brainstem separately homogenized to measure the activity of thiobarbituric acid reactive substances (TBARS) and ATPase in the presence and absence of ouabain. The activity of Na+/K+ ATPase increased in cerebellum of well-nourished rats exposed to ozone, while total ATPase and TBARS decreased in all studied areas in the malnourished groups. These results suggest that nutritional status and exposure to ozone generate changes in lipid membrane composition, in turn changing the activity of sodium pump with similar consequences for brain metabolism.

TBARS

Thiobarbituric acid

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Citations (1)

Morphine Alters Calcium Levels and ATPase Activity in the Brain Regions of Rats with Insulin-induced Hypoglycemia

Asian Journal of Biological Sciences (2014)

David Calderón Guzmán Gerardo Barragán Mejía Ernestina Hernández García Hugo Juárez Olguı́n Norma Labra Ruíz

10.3923/ajbs.2014.172.177

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Citations (0)