Objetivo: Avaliar a alteração da função cardÃaca em pacientes com câncer de mama tratadas com quimioterapia. Métodos: Estudo observacional retrospectivo com coleta de dados em prontuário no Hospital Mário Covas (Santo André â Brasil). Avaliou-se a fração de ejeção obtida pelo ecocardiograma (ECO) antes do tratamento quimioterápico, em comparação com o ECO ao final do tratamento. Resultados: Foram incluÃdas 234 pacientes com câncer de mama submetidas a QT, das quais 100 realizaram ao menos um ECO e 33, pelo menos dois exames. Desse total, apenas 18 puderam ser analisados, pois apresentavam ECO feito corretamente, i.e., antes e depois do tratamento quimioterápico. Analisando esses ECOs, observou-se diferença da fração de ejeção média de 5% (IC95% 2,9-7,6; p=0,0001). Conclusão: A alta prevalência e o expressivo aumento da sobrevida de pacientes com câncer de mama indicam a necessidade de acompanhamento adequado dos efeitos a longo prazo da QT. A análise dos ECO feitos adequadamente nos pacientes com câncer de mama nesse estudo demonstrou significante queda da fração de ejeção, confirmando os efeitos cardiotóxicos da QT. Apesar disso, apenas uma fração pouco expressiva dos pacientes apresentou acompanhamento adequado.
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