Journal Article Assessment of Biological Age by Multiple Regression Analysis Get access Toshiyuki Furukawa, MD, PhD, Toshiyuki Furukawa, MD, PhD Search for other works by this author on: Oxford Academic PubMed Google Scholar Michitoshi Inoue, MD, PhD, Michitoshi Inoue, MD, PhD Search for other works by this author on: Oxford Academic PubMed Google Scholar Fumihiko Kajiya, MD, Fumihiko Kajiya, MD Search for other works by this author on: Oxford Academic PubMed Google Scholar Hiroshi Inada, MD, PhD, Hiroshi Inada, MD, PhD Search for other works by this author on: Oxford Academic PubMed Google Scholar Seiichi Takasugi, MD, Seiichi Takasugi, MD Search for other works by this author on: Oxford Academic PubMed Google Scholar Sugao Fukui, MD, Sugao Fukui, MD Search for other works by this author on: Oxford Academic PubMed Google Scholar Hiroshi Takeda, MD, Hiroshi Takeda, MD Search for other works by this author on: Oxford Academic PubMed Google Scholar Hiroshi Abe, MD, PhD Hiroshi Abe, MD, PhD 1First Dept. of Medicine, Osaka Univ. Medical SchoolOsaka, Japan. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Gerontology, Volume 30, Issue 4, July 1975, Pages 422–434, https://doi.org/10.1093/geronj/30.4.422 Published: 01 July 1975
Digital radiography (100 pixels/mm2) combined with the technique of 3H-labeled desmethylimipramine deposition was employed to visualize regional blood flow distributions in rabbit left ventricular myocardium. A fluctuated pattern of myocardial flow and its dependence on arterial oxygen tension (PaO2) was evaluated with the coefficient of variation (CV) computed at each step of coarse-graining; flow images were revisualized by increasing pixel area (PA) step by step from 0.01 to 1 mm2. The CV values decreased with hypoxia at all resolution levels, suggesting that there is a vascular regulatory mechanism for making myocardial perfusion uniform in response to decreased PaO2. In both perfusion states, CV decreased with increasing PA. The relationship between CV and PA fitted the noninteger power law function, implying an apparent fractality of CV.
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