Vijay S. Ramanath

Plano Cancer Institute

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Kim A. Eagle

Michigan Medicine

James B. Froehlich

Michigan Medicine

Aaron V. Kaplan

Dartmouth–Hitchcock Medical Center

Craig A. Thompson

Purdue University West Lafayette

Jeremiah R. Brown

Dartmouth College

John F. Robb

Dartmouth–Hitchcock Medical Center

Eric M. Isselbacher

University of Michigan–Ann Arbor

Christoph Nienaber

Imperial College London

Nathaniel W. Niles

Dartmouth–Hitchcock Medical Center

Bruce Hettleman

Dartmouth–Hitchcock Medical Center

Cooperative Institutions

University of Michigan–Ann Arbor

Michigan Medicine

Society of Thoracic Surgeons

University of Pittsburgh

Johns Hopkins University

Brigham and Women's Hospital

Dartmouth–Hitchcock Medical Center

Harvard University

RELX Group (United States)

Vall d'Hebron Hospital Universitari

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Type-Selective Benefits of Medications in Treatment of Acute Aortic Dissection (from the International Registry of Acute Aortic Dissection [IRAD])

The American Journal of Cardiology (2011)

Toru Suzuki Eric M. Isselbacher Christoph Nienaber Reed E. Pyeritz Kim A. Eagle

Univariate analysis

10.1016/j.amjcard.2011.08.012

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Citations (209)

Outcomes of diabetics receiving bare‐metal stents versus drug‐eluting stents

Catheterization and Cardiovascular Interventions (2010)

Vijay S. Ramanath Jeremiah R. Brown David J. Malenka James T. DeVries Mandeep S. Sidhu

Abstract Objectives : We sought to determine if differences existed in in‐hospital outcomes, long‐term rates of target vessel revascularization (TVR), and/or long‐term mortality trends between patients with diabetes mellitus undergoing percutaneous coronary intervention (PCI) with either a drug‐eluting stent(s) (DES) or a bare metal stent(s) (BMS). Background : Short‐ and long‐term clinical outcomes of patients with diabetes mellitus undergoing PCI with DES versus BMS remain inconsistent between randomized‐controlled trials (RCTs) and observational studies. Methods : Data were collected prospectively on diabetics undergoing PCI with either DES or BMS from January 2000 to June 2008. Demographic information, medical histories, in‐hospital outcomes, and long‐term TVR and mortality trends were obtained for all patients. Results : A total of 1,319 patients were included in the study. Diabetics receiving DES had a significant reduction in index admission MACE compared to diabetics receiving BMS. Using multivariable adjustment, after a mean follow‐up of 2.5 years (maximum 5 years), diabetics who received DES had a 38% decreased risk of TVR compared to diabetics with BMS [HR 0.62 (95% CI: 0.43–0.90)]; diabetics with DES had an insignificant adjusted improvement in long‐term survival compared to diabetics with BMS [HR 0.72 (95% CI: 0.52–1.00)]. These long‐term survival and TVR rates were confirmed using propensity scoring. Conclusions : The use of DES when compared with BMS among diabetics undergoing PCI is associated with significant improvement in long‐term TVR, with an insignificant similar trend in all‐cause mortality. The long‐term results of this observational study are consistent with prior RCTs after adjusting for confounding variables. © 2010 Wiley‐Liss, Inc.

Mace

10.1002/ccd.22512

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Citations (6)

Coronary Chronic Total Occlusion Recanalisation - Current Techniques and Approaches

Vijay S. Ramanath Craig A. Thompson

Coronary chronic total occlusions (CTOs) are among the most challenging coronary artery lesions to treat percutaneously. In the last decade, great strides have been made to develop techniques to improve success rates. While success rates among high-volume operators are >90 %, non-CTO operators still continue to struggle with this lesion subset. Thus, efforts have been made to develop algorithms to help operators achieve successful recanalisation consistently and improve patient outcomes. The North American Total Occlusion (NATO) algorithm emphasises dual coronary injection using two guide catheters, which allows for switching from an antegrade to retrograde approach or vice versa should the initial strategy fail - the so-called 'hybrid' approach. Special attention is paid to four angiographic characteristics: 1) location of the proximal cap, 2) lesion length, 3) presence and suitability of collateral vessels for retrograde crossing and 4) location and quality of target vessel distal cap. The ultimate goal of this algorithm is to provide a strategy to achieve successful CTO revascularisation while using the least amount of fluoroscopy, contrast and equipment possible.

Target lesion

Coronary occlusion

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Citations (1)

Response to the Letter to the Editor by Shams Y-Hassan, M.D.: “DINO and Medina coronary bifurcation lesion classifications” (CRM-D-12-00096)

Cardiovascular revascularization medicine (2012)

David M. Zlotnick Vijay S. Ramanath Jeremiah R. Brown Aaron V. Kaplan

10.1016/j.carrev.2012.09.001

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Citations (0)

The association between guideline-based treatment instructions at the point of discharge and lower 1-year mortality in Medicare patients after acute myocardial infarction: The American College of Cardiology's Guidelines Applied in Practice (GAP) initiative in Michigan

American Heart Journal (2007)

Adam M. Rogers Vijay S. Ramanath Mary Grzybowski Arthur Riba Sandeep M. Jani

Guideline

Odds

10.1016/j.ahj.2007.05.003

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Citations (69)

A quality guarantee in acute coronary syndromes: The American College of Cardiology's Guidelines Applied in Practice program taken real-time

American Heart Journal (2006)

Smit C. Vasaiwala Elizabeth Nolan Vijay S. Ramanath Jiaming Fang Gwen Kearly

Clinical Practice

10.1016/j.ahj.2006.09.002

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Citations (36)

1-Year Results From the RANGER II SFA Randomized Trial of the Ranger Drug-Coated Balloon

КАРДИОЛОГИЯ УЗБЕКИСТАНА (2021)

Ravish Sachar Yoshimitsu Soga Mohammad M. Ansari Amane Kozuki Louis Lopez

This study sought to evaluate the safety and effectiveness of the Ranger drug-coated balloon (DCB) (paclitaxel dose density 2 μg/mm2) for treating superficial femoral artery or proximal popliteal artery lesions.Paclitaxel-coated balloon treatment prevents reinterventions, but dose and coating characteristics differ among balloons and necessitate discrete confirmation of safety and effectiveness.Patients with symptomatic lower limb ischemia (Rutherford classification 2 to 4) were randomized 3:1 to treatment with the Ranger DCB or standard percutaneous transluminal angioplasty (PTA). Twelve-month primary target lesion patency, freedom from major adverse events (i.e., target lesion revascularization, major amputations, death within 1 month of the index procedure), and patient outcomes were analyzed.Mean lesion length was 82.5 ± 48.9 mm for the Ranger DCB group (n = 278) and 79.9 ± 49.3 mm for the control group (n = 98). Ranger DCB was superior to PTA (82.9% [n = 194 of 234] vs. 66.3% [n = 57 of 86]) with observed 12-month primary patency rates yielding a difference of 16.6% (95% confidence interval: 5.5% to 27.7%; p = 0.0013). Noninferior freedom from major adverse events (94.1% [n = 241 of 256] vs. 83.5% [n = 76 of 91]) was demonstrated with a difference of 10.6% (95% confidence interval: 2.5% to 18.8%; noninferiority p < 0.0001). Primary patency rate curves showed significant separation by Kaplan-Meier analysis (log-rank p = 0.0005), with rates of 89.8% and 74.0% estimated at day 365 for the Ranger DCB and PTA cohorts, respectively.The low-dose Ranger DCB demonstrated significantly better effectiveness than standard PTA through 1 year and a good safety profile. (Ranger™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty [RANGER II SFA]; NCT03064126).

Popliteal artery

Target lesion

10.1016/j.jcin.2021.03.021

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Citations (52)

Contents

The Annals of Thoracic Surgery (2013)

Edmund S. Kassis Andrzej S. Kosinski Patrick Ross Katherine E. Koppes James G. Donahue

10.1016/s0003-4975(13)02427-2

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Diagnosis of pulmonary embolism by acute right heart morphologic and hemodynamic changes observed during exercise stress echocardiography