Pavel S. Vydrin

S. M. Kirov Military Medical Academy

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Svetlana N. Kalinina

North-Western State Medical University named after I.I. Mechnikov

Oleg O. Burlaka

St. Petersburg State Medical Academy "City Hospital No. 26"

D. G. Korenkov

North-Western State Medical University named after I.I. Mechnikov

Irina S. Gonchar

S. M. Kirov Military Medical Academy

S. A. Zamyatnin

Saint Petersburg State Pediatric Medical University

V. N. Fesenko

North-Western State Medical University named after I.I. Mechnikov

МВ

Михаил Вениаминович Мошарев

Alexandrovska Hospital

Vladimir V. Chrishtop

S. M. Kirov Military Medical Academy

AА

Alexey А. Semenov

S. M. Kirov Military Medical Academy

Vladimit Yu Startsev

North-Western State Medical University named after I.I. Mechnikov

Cooperative Institutions

North-Western State Medical University named after I.I. Mechnikov

Ministry of Health of the Russian Federation

S. M. Kirov Military Medical Academy

Alexandrovska Hospital

St Petersburg University

Saint Petersburg State Pediatric Medical University

ITMO University

Ufa Research Institute of Occupational Health and Human Ecology

Ivanovo State Medical Academy

Military Medical Academy

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Assessment of copulative function and severity of lower urinary tract symptoms in patients with benign prostatic hyperplasia after transurethral enucleation

Urology reports (St - Petersburg) (2021)

Pavel S. Vydrin Svetlana N. Kalinina Oleg O. Burlaka Michail S. Aleksandrov

AIM: was to conduct a comparative assessment of copulative function and the severity of lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH) who underwent laser and bipolar transurethral enucleation of the prostate and who treated conservatively. MATERIALS AND METHODS: 143 BPH patients aged 50 to 80 years (mean age 65 years) with complaints of copulatory and urinary disorders were under observation. All patients were divided into two groups. The 1st (main) group included 102 patients who underwent surgical treatment: transurethral laser enucleation of the prostate (n = 55) and transurethral bipolar enucleation of the prostate (n = 47). Patients of the 2nd group (n = 41) received conservative treatment. Control examinations were performed before treatment, 4, 12 and 24 weeks after it. RESULTS: All 102 patients of group 1, regardless of the type of surgery, noted retrograde ejaculation four weeks after surgery. In the majority of patients of the 1st group during these periods weakening of orgasm was noted, in a significant number deterioration of erection and decreased libido were noted. Upon further observation, by the 12th week after the operation, restoration of all components of the copulatory function was noted, with the exception of ejaculation. By the 24th week of observation, only in 2 patients of the 1st group the normal mechanism of ejaculation was restored. Surgical treatment of patients in group 1, regardless of the method of surgery, led to a significant decrease in the severity of LUTS, an increase in the maximum urine flow rate, a decrease in the volume of the prostate gland and the amount of residual urine. There were no significant differences in the dynamics of these indicators depending on the method of transurethral enucleation. The patients of the 2nd group also had an improvement in clinical parameters, but it was much less pronounced than in the 1st group. CONCLUSION: Laser and bipolar transurethral enucleation of the prostate are effective surgical techniques that significantly improve the outflow of urine from the bladder, reduce the severity of LUTS and improve the sexual function of patients. Surgery is well tolerated by patients. At the same time, almost all patients operated on by these methods develop retrograde ejaculation.

Ejaculation

Retrograde ejaculation

10.17816/uroved55409

Cite

Citations (2)

Influence of constitutional typology on human cell-tissue homeostasis: A review

Morphology (2024)

Vladimir V. Chrishtop Ivan V. Gaivoronsky Л. М. Железнов Аlexey I. Gaivoronsky Alexey А. Semenov

Historically, the formation of body types by a number of authors is inextricably linked with the tissue structure of the human body and embryogenesis, as evidenced by the works of W. Sheldon and A.A. Bogomolets. Taking into account the need of modern medicine for personalized diagnostics, the goal was set: to assess the state of the interdisciplinary segment of research at the intersection of data on body types and structural features of organs and tissues. The results obtained indicate that existing research in this area is fragmented. At the same time, the features of the histological structure of nervous, bone, connective tissue and blood were demonstrated. The results obtained indicate that existing research in this area is fragmented. At the same time, the features of the histological structure of nervous, bone, connective tissue and blood were demonstrated. The structural features of the digestive system organs of different body types are shown. Data on the male and female reproductive systems are quite widely presented. The results obtained allow us to consider the somatotyping method in the context of modern personalized medicine. Systematization and further study of constitutional tissue patterns will be an invaluable contribution to fundamental anatomy, as a science that combines micro- and macroanatomical features of the body, which will form the fundamental basis for early diagnosis and prevention of diseases of internal organs.

Human body

10.17816/morph.627409

Cite

Citations (2)

Treatment and prevention of reproductive disorders, oxidative stress in male idiopathic infertility

Фармакология & Фармакотерапия (2020)

Svetlana N. Kalinina Vladimit Yu Startsev Pavel S. Vydrin S. A. Zamyatnin Irina S. Gonchar

Male reproductive system

10.46393/2713-2129_2020_72-80

Cite

Citations (0)

Results of ultrasound dopplerography of the penis in patients with before and after transurethral enucleation of benign prostatic hyperplasia

Urology reports (St - Petersburg) (2021)

Pavel S. Vydrin Svetlana N. Kalinina D. G. Korenkov

BACKGROUND: The development of modern technologies for the surgical treatment of urological diseases poses new questions for urologists. One of them is to evaluate the effect of transurethral enucleation of benign prostatic hyperplasia on the erectile function of patients. AIM: The aim of the study was to assess the state of erectile function in patients before and after transurethral enucleation of benign prostatic hyperplasia using Doppler ultrasound of the vessels of the penis. MATERIALS AND METHODS: The study included 102 patients with benign prostatic hyperplasia aged 50 to 80 years (average 65 years) with complaints of erectile dysfunction and urinary disorders. All patients underwent transurethral enucleation of benign prostatic hyperplasia: 55 patients with the laser method (HoLEP, group 1) and 47 patients with the bipolar method (TUEB, group 2). The severity of ED was assessed using the IIEF-5 questionnaire (International Index of Erectile Function). To assess the state of blood flow in the penis, ultrasound dopplerography of the vessels of the penis was performed using a vasoactive erection stimulator. The studies were carried out before surgery and 24 weeks after it. RESULTS: The results of ultrasound dopplerography of the vessels of the penis before surgery revealed the arteriogenic type of ED in 18 (17.6%) patients, the venous type in 45 (44.2%) patients, the mixed arteriovenogenic type in 22 (21.6%) patients. In 17 (16.7%) patients ED was regarded as psychogenic. 24 weeks after the operation in patients of both the 1st and 2nd groups, according to the data of the IIEF-5 questionnaire, positive dynamics of the severity of erectile function was noted, regardless of the type of ED. For patients with vasculogenic types of ED, similar trends were noted regardless of the type of surgery. Thus, in patients with arteriogenic and arteriovenogenic ED a significant increase in the maximum systolic blood flow velocity (Vmax) in the cavernous arteries was recorded, while the values of the resistance index (RI) did not change significantly. At the same time, the Vmax values in these patients were initially low before the operation, and after the operation did not reach the reference values. In patients with venogenic ED, there was no significant improvement in penile blood flow, as evidenced by the absence of significant differences in Vmax and RI values. At the same time, the RI in these patients before the operation was reduced, and the Vmax values were in the range of normal values. CONCLUSIONS: The erectile function of patients after transurethral enucleation of benign prostatic hyperplasia improves regardless of the type of operation and the type of erectile dysfunction. Ultrasound dopplerography of the vessels of the penis is a minimally invasive and highly informative diagnostic method that makes it possible to detect circulatory disorders in the penis and assess its state in dynamics during treatment.

Psychogenic disease

10.17816/uroved89701

Cite

Citations (1)

TREATMENT OF ACUTE URINARY RETENTION CAUSED BY BENIGN PROSTATE HYPERPLASIA IN THE UROLOGY DEPARTMENT OF HOSPITAL

EMERGENCY MEDICAL CARE (2019)

Svetlana N. Kalinina Oleg O. Burlaka M. S. Alexandrov Pavel S. Vydrin

In the article the results of conservative and operative treatment of 122 patients ranging in age from 42 to 80 years of age with acute delay of urine caused by benign prostate hyperplasia in the urology Department Alexander Hospital 2016 to 2018 years. n men, the most common cause of SSM is safe giperplazia (adenoma) prostate (BPH), found in the 45–53% of observations, tending to cause heart attacks in prostate tissue and increased Alpha-adrenergic activity. The main pathogenetic factor SSM in men is BPH, where heart attacks occur in the prostate tissue and increased Alpha-adrenergicheskaja activity. In 1 group comprised 42 patients diagnosed for the first time, SSM, caused by BPH, in Group 2–80 patients with multiple SSM caused by BPH. All patients of Group 1 after combination therapy of Alpha alfuprost MICRORAION adrenoblokatorom in combination with jelefloksom noted restore self-sustaining urination. In Group 2 at 72 patients recovered partially and urinating they have plus sizes BPH, they performed Transurethral enucleation of BPH with positive effect.

Urination

Urinary retention

10.24884/2072-6716-2019-0-3-46-51

Cite

Citations (1)

Тактика лечения больных при перекруте яичка

Urology reports (St - Petersburg) (2019)

Светлана Николаевна Калинина V. N. Fesenko Oleg O. Burlaka Михаил Вениаминович Мошарев Михаил Сергеевич Александров

Source

Cite

Citations (0)

Assessment of blood flow in the prostate before and after transuretral enucleation of benign hyperplasia prostate

Urology reports (St - Petersburg) (2022)

Pavel S. Vydrin Svetlana N. Kalinina D. G. Korenkov

BACKGROUND: Transrectal Doppler ultrasound is the leading method for studying blood flow in the prostate. Despite a significant number of studies on the use of ultrasound of the prostate in patients with BPH, many aspects of its clinical use remain unclear. One of these issues is the features of changes in blood flow in the prostate after transurethral surgical interventions. AIM: to assess the state of blood flow in the prostate gland in patients with BPH before and after transurethral enucleation by laser and bipolar methods. MATERIALS AND METHODS: The study included 88 patients with BPH aged 50 to 79 years who complained of urinary disorders. All patients underwent transurethral enucleation of BPH: 41 patients with the laser method (HoLEP) (1st group) and 47 patients with the bipolar method (TUEB) (2nd group). Before surgical treatment, 4, 12 and 24 weeks after surgery, patients underwent transrectal Doppler ultrasound of the prostate. RESULTS: The results of the study indicate a significant impact of surgery on the state of blood flow in the prostate gland. Examination 12 weeks after the operation showed a significant decrease in the peak blood flow velocity and values of the resistance index in patients of the 1st and 2nd groups compared with the corresponding values before the surgery and 4 weeks after the surgery. By 24 weeks after surgery, all patients showed normalization of blood flow parameters, while in patients of the 1st group (HoLEP) this process occurred faster than in patients of the 2nd group (TUEB). CONCLUSIONS: The high diagnostic efficiency and informativeness of transrectal Doppler ultrasound in the assessment of blood circulation in the prostate in patients with BPH has been confirmed. The blood flow velocity in the subcapsular and especially paraurethral arteries, as well as the values of the resistance index, were higher in patients with large prostates, which must be taken into account when planning surgical interventions.

10.17816/uroved105171

Cite

Citations (1)