Abstract : This report summarizes Air Force use of hydrazines; exposure potential, experience and control techniques; instrumentation requirements, capabilities and limitations: spill management techniques: and management and control of acute exposures. It contains a review of American, German, Swedish, Russian and international agency for research on cancer workplace air standards for hydrazines and related compounds, and a selective literature review of recent important information deemed useful relative to establishing health standards for environmental exposure to the hydrazines, nitrosamines, nitrosomethylureas and nitrosomethylurethane. In addition, there is an appendix containing a comprehensive list of subject references on toxicity and biological effects of the hydrazines and their derivatives. (Author)
Abstract This study documented the formaldehyde exposures of a group of veterinary medicine students. It also investigated the feasibility of biologically monitoring the exposures. The biological monitoring was based on the fact that the formaldehyde is metabolized in the body to formic acid, and may then be excreted in the urine. Therefore, exposures to formaldehyde could theoretically create a shift in the formic acid levels in the urine. Normal baseline levels of urinary formic acid were first established for each subject. The baselines of most students were quite variable. Very few exhibited a “tight variability” in their baseline. Next, three sets of pre- and post-exposure urine samples were taken. A series of paired t-tests were run on these “pre” and “post” sets. The results indicated that no significant formic acid shift was seen. A subset of the samples was “corrected” for specific gravity. However, this adjustment did not have an effect upon the relative formic acid levels. In addition, no significant formic acid shift was seen in the adjusted group. Exposure levels of the students were less than 0.5 ppm of formaldehyde. Therefore, the main conclusion of the study was that biological monitoring of formaldehyde exposures (via formic acid shifts) at these low levels was not a feasible technique.
This study documented the formaldehyde exposures of a group of veterinary medicine students. It also investigated the feasibility of biologically monitoring the exposures. The biological monitoring was based on the fact that the formaldehyde is metabolized in the body to formic acid, and may then be excreted in the urine. Therefore, exposures to formaldehyde could theoretically create a shift in the formic acid levels in the urine. Normal baseline levels of urinary formic acid were first established for each subject. The baselines of most students were quite variable. Very few exhibited a "tight variability" in their baseline. Next, three sets of pre- and post-exposure urine samples were taken. A series of paired t-tests were run on these "pre" and "post" sets. The results indicated that no significant formic acid shift was seen. A subset of the samples was "corrected" for specific gravity. However, this adjustment did not have an effect upon the relative formic acid levels. In addition, no significant formic acid shift was seen in the adjusted group. Exposure levels of the students were less than 0.5 ppm of formaldehyde. Therefore, the main conclusion of the study was that biological monitoring of formaldehyde exposures (via formic acid shifts) at these low levels was not a feasible technique.
Pollution emissions from three representative types of jet engines were determined. Pollutants measured included nitrogen oxides, aldehydes, carbon monoxide, hydrocarbons, and odors. A method is presented for determining the magnitude of pollution emissions due to commercial jet aircraft operation by using basic emission factors.
Abstract The seal of a respirator to a worker's face can be influenced by the worker's facial dimensions. Males and females of the same and different racial/ethnic backgrounds exhibit different facial dimension measurements. This research was conducted to ascertain the relationship between facial dimensions influenced by race/ethnicity and gender to respirator fit. Facial dimensions and respirator fit were measured on 186 subjects from three racial/ethnic groups: 34 white American females, 32 white American males, 29 African-American females, 29 African-American males, 30 Mexican-American males, and 32 Mexican-American females. Fourteen facial dimension measurements were measured on each subject. A multiple analysis of variance indicated that facial dimensions between gender and race/ethnicity were significantly different (p = 0.0001). Quantitative fit tests were performed on each subject using the TSI PortaCount™ and MSA Advantage half-mask, air-purifying respirators. Subjects were fit with a small, medium, or large respirator, and respirator fit was measured by the calculation of a fit factor for each subject. Fit factor data were log transformed (LNFFs) to achieve a normal distribution. A Pearson's correlation between facial dimensions and LNFFs indicated that only nose protrusion was significantly associated with respirator fit (p = 0.0296). A multiple analysis of variance indicated that facial dimensions based on gender, race/ethnicity, and the interaction of the two were not significantly associated with respirator fit. Linear regression analysis indicated that nose protrusion and nose width accounted for 4.45 percent of the variance observed in respirator fit. It was concluded that respirator fit was not associated with facial dimensions based on race/ethnicity or gender. Respirator fit seemed to be associated with individual facial characteristics rather than facial characteristics associated with racial/ethnic groups or gender.