Jason Boyer

New York University Langone Orthopedic Hospital

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Peter S. Walker

New York University Langone Orthopedic Hospital

Gökçe Yıldırım

Bingöl University

Jonathan Sussman-Fort

BAE Systems (Sweden)

Bert R. Mandelbaum

Cedars-Sinai Kerlan-Jobe Institute

Marco Delcogliano

Università della Svizzera italiana

Jack Farr

Indiana Orthopaedic Hospital

James Bicos

Beaumont Hospital, Royal Oak

Andrew I. Su

Scripps Research Institute

Serge Batalov

Rady Children's Hospital-San Diego

Chunlei Wu

China University of Petroleum, East China

Cooperative Institutions

Genomics Institute of the Novartis Research Foundation

San Diego State University

University of Gothenburg

Technical University of Munich

University of Pittsburgh Medical Center

Scripps Research Institute

University of California, San Diego

Washington University in St. Louis

Western University

New York University Langone Orthopedic Hospital

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Double-bundle versus single-bundle ACL reconstruction.

PubMed (2010)

Jason Boyer Robert J. Meislin

Surgical repair of the anterior cruciate ligament is a fairly common necessity in knee injuries, usually with good to excellent outcomes. However a successful repair and return to activities for a subpopulation of patients, 10% to 30%, remain elusive. Additionally, some athletes have arthritic changes, even with ligament repair. These issues are likely multi-factorial in nature but the debate continues even over which primary operative technique will produce the most favorable outcome. This review examines and discusses the anatomic and historical rationale of double-bundle ACL reconstruction techniques, the published kinematics of double-bundle reconstructions, and the clinical literature comparing double-bundle outcomes to those of the more traditional single-bundle constructs. Conclusions regarding surgical care include a need for more standardization of measuring parameters and the future application of advanced technologies that would inform more correct models of knee kinematics for comparison to various ACL construction approaches, potentially allowing improvement in the techniques of ACL reconstruction.

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Citations (12)

Design Features of Total Knees for Achieving Normal Knee Motion Characteristics

The Journal of Arthroplasty (2008)

Peter S. Walker Jonathan Sussman-Fort Gökçe Yıldırım Jason Boyer

Rollback

10.1016/j.arth.2007.11.002

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Citations (31)

Total knees designed for normal kinematics evaluated in an up‐and‐down crouching machine

Journal of Orthopaedic Research® (2009)

Gökçe Yıldırım Peter S. Walker Jason Boyer

Abstract We constructed a crouching machine to study the motion of the knee joint, in which a motor was used to wind the quadriceps tendon so as to move the knee from high flexion to extension and back into flexion, while springs simulated hamstrings forces. Seven human cadaveric knees were tested intact and then after anterior cruciate ligament (ACL) resection. Motions of the femur, tibia, and patella were recorded by an optical tracking system. We then inserted plastic models representing commonly used total condylar and posterior stabilized knee replacement designs. Femoral motion was described by successive positions of the transverse axis of the femur projected onto the tibial surface. In the knee replacements, motions were similar to that of an ACL‐deficient knee. We then tested two new designs with features intended to prevent anterior paradoxical sliding and to promote a medial pivot motion with femoral rollback primarily on the lateral side. The motion path more closely followed that of the normal intact knee. We concluded that motion guiding features in a total knee replacement could reproduce a normal neutral path that might result in functional improvements for the patient. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27: 1022–1027, 2009

Cadaveric spasm

Quadriceps tendon

10.1002/jor.20839

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Citations (24)

Contributors

Elsevier eBooks (2010)

Jens D. Agneskirchner Peter Behrens Jan Philipp Benthien James Bicos Brice W. Blatz

10.1016/b978-1-4377-0878-3.10028-2

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Alaska Wastewater Standards

Coast Guard Journal of Safety & Security at Sea, Proceedings of the Marine Safety & Security Council (2014)

Jason Boyer

Alaska’s Inside Passage has many areas that are a far enough distance from the shore that vessels were allowed to legally discharge sewage and gray water without restriction. This was known as the doughnut hole loophole. The loophole was closed in 2000, when legislation was introduced that made it illegal for large cruise ships to discharge without meeting strict regulations. All cruise ships in Alaskan waters are subject to compliance inspection and enforcement for noncompliance with applicable regulations. The program has been successful in maximizing compliance and reducing harm to the environment.

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Next Generation Knee Replacements: A New Approach to Replicate the Function of the ACL

ASME 2007 Summer Bioengineering Conference (2007)

Gökçe Yıldırım Peter S. Walker Jonathan Sussman-Fort Jason Boyer

Current total knee replacements solve the problem of arthritic knee joints, but the evidence is that normal patterns of knee motions are not restored (1) In addition; paradoxical anterior sliding of the femur on the tibia can occur in the first half of the flexion range (2). Achieving natural motion is likely to be important for daily activities which involve higher angles of flexion, in terms of restoring normal soft tissue lengths and patello-femoral mechanics. Studies have shown the damaging effects of anterior femoral slide on the tibia affecting both the patella and the patellar tendon (3). Our paper examines new knee replacement designs which incorporate geometrical features to regain anatomical knee motion.

Knee flexion

Biomechanics

Quadriceps tendon

10.1115/sbc2007-176201

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Citations (1)

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

Genome biology (2009)

Chunlei Wu Camilo Madariaga Orozco Jason Boyer Marc Leglise James Goodale

Online gene annotation resources are indispensable for analysis of genomics data. However, the landscape of these online resources is highly fragmented, and scientists often visit dozens of these sites for each gene in a candidate gene list. Here, we introduce BioGPS http://biogps.gnf.org, a centralized gene portal for aggregating distributed gene annotation resources. Moreover, BioGPS embraces the principle of community intelligence, enabling any user to easily and directly contribute to the BioGPS platform.

Human genetics

Gene Annotation

Extensibility

Genome Biology

10.1186/gb-2009-10-11-r130

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Citations (1,352)

Patient Evaluation and Treatment Algorithms

Elsevier eBooks (2010)

Marco Delcogliano Jason Boyer Bert R. Mandelbaum

10.1016/b978-1-4377-0878-3.10002-6

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