Kalikhevich Vn

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Ardemasova Za

Kharchenko Ep

Institute of Evolutionary Physiology and Biochemistry

Shestak Ki

ТВ

Т. В. Соколова

Institute of Evolutionary Physiology and Biochemistry

Kamenskiĭ Aa

Lomonosov Moscow State University

Churkina Si

Sarycheva NIu

Koval'zon Vm

Severtsov Institute of Ecology and Evolution

Barashkova Gm

M Kimura-Takeuchi

Zhejiang University Medical College Affiliated Stomatological Hospital

Cooperative Institutions

Ministry of Health of the Russian Federation

Russian Academy of Sciences

Lomonosov Moscow State University

University of Tennessee Health Science Center

Institute of Evolutionary Physiology and Biochemistry

University of Szeged

Severtsov Institute of Ecology and Evolution

Zhejiang University Medical College Affiliated Stomatological Hospital

The University of Tokyo

Kyushu University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

[Effect of low-molecular peptides on the transformation of fibrinogen into fibrin].

PubMed (1987)

Levitskaia Ng Kleĭmenov An Petrosian Mt Rozenfel'd Ma Kalikhevich Vn

The influence of synthetic peptides on fibrinogen transformation to fibrin under the action of thrombin and fibrin-monomer polymerization was investigated. Peptides Gly-Pro-Arg-Pro; Gly-Pro-Arg-Pro-Lys; Gly-Pro-Arg-Pro-Lys-Boc; Gly-Pro-Arg-Pro-Arg are specific inhibitors of fibrin formation. These peptides interfere with the hydrolysing effect of thrombin due to binding to the central domain of fibrinogen. The interaction of peptides with peripheral D-domains of fibrin-monomer may account for polymerization inhibition. The latter peptide has the largest anticoagulation activity. It is likely that arginine in the fifth position stabilizes the structure of the peptides, with the additional epsilon NH2-group activating its interaction with protein.

Source

Cite

Citations (1)

[The effect of synthetic opiate-like peptides identical to protein fragments with different functions and their structural analogs on the basal activity of the striatal adenylate cyclase in the rat brain].

PubMed (1998)

Shestak Ki Kalikhevich Vn Ardemasova Za

Opiate

Basal (medicine)

Endorphins

Source

Cite

Citations (0)

[Synthesis of poly-S-carbobenzomethoxy-L-cysteine and studies on its structure].

PubMed (1965)

Anufrieva Ev Volchek Bz Illarionova Ng Kalikhevich Vn Korotkina Oz

Source

Cite

Citations (6)

[Peptidergic modulation of sleep: a comparative study of analogs of the peptide DSIP].

PubMed (1986)

Koval'zon Vm F. Obál Kalikhevich Vn

Effects of intracerebroventricular administration of 3 DSIP analogues with higher stability against proteolysis, on subsequent sleep were studied in rabbits and rats previously implanted with electrodes and cannulas. Significant increase of total sleep time (mainly due to slow wave sleep) after administration of the peptides (D-Trp1) DSIP and (D-Tyr1) DSIP as compared with the control injections to the same animals was found during the first 3-5 hours in rabbits and 12 hours in rats. Shortened analogue (D-Trp1) DSIP1-6 had no effect on rabbit sleep and significantly reduced slow wave sleep in rats during the first 3 hours. It is concluded that some DSIP-like peptides which are more stable against aminopeptidases, can modulate rodent sleep.

Sleep

Proteolysis

Source

Cite

Citations (2)

[Adrenopeptide connections in the mechanisms regulating gastric secretory function in dogs].

PubMed (1992)

Barashkova Gm Klimov Pk Kalikhevich Vn

Source

Cite

Citations (0)

[The elimination of disorders in the acquisition of a conditioned active avoidance reaction by using the C-termination fragment of lysyl vasopressin].

PubMed (1988)

С. А. Титов Shamakina IIu Nikonova Ab Voskresenskaia Og Kalikhevich Vn

In experiments with male white rats it was shown that 0.001 and 0.01 mg/kg of lysyl vasopressin C-terminal fragment--Pro-Lys-Gly (PLG) being injected intraperitoneally fails to influence the acquisition of active and passive avoidance and also T-maze food rewarded behaviour. The injection of PLG removed by disturbances of active avoidance caused by cyproheptadine and oxytocin. The inhibition of passive avoidance and food-rewarded behaviour was not removed by PLG.

Active compound

Avoidance response

Source

Cite

Citations (0)

[Peptide antibiotics based on a fragment from human preproenkephalin A].

PubMed (1989)

Kharchenko Ep Samedov ASh Kalikhevich Vn Ardemasova Za Т. В. Соколова

Fragment (logic)

Source

Cite

Citations (0)

[Opiate-like non-enkephalin peptides].

PubMed (1988)

Kharchenko Ep Kalikhevich Vn Т. В. Соколова Shestak Ki Ardemasova Za

Opiate

Endorphins

Source

Cite

Citations (1)

[Taftsin correction of pharmacologically induced behavioral disorders in white rats].

PubMed (1987)

Ashmarin Ip Syracheva NIu Т.И. Власова Kalikhevich Vn Kamenskiĭ Aa

Tetrapeptide tuftsin in doses adapted to its physiological blood concentrations partially normalized locomotor activity and orientation behaviour of rats altered by drugs affecting aminergic brain systems. At the same time tuftsin had no effect when applied after the treatment by dopaminergic drugs (DTC, haloperidol, apomorphine). It can be concluded that the central effect observed in the first minutes after tuftsin administration is mediated through dopaminergic system. Elimination of some drug-induced behavioural disturbances by tuftsin opens new prospects for its therapeutic application.

Tuftsin

Apomorphine

Tetrapeptide

Source

Cite

Citations (0)

[Use of angiotensin II to control systemic arterial pressure].

PubMed (1981)

Pugovkin Ap Kalikhevich Vn Ardemasova Za Osadchiĭ Li

Source

Cite

Citations (0)