Ivan Požgain

University of Osijek

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Pavo Filaković

University of Osijek

Ninoslav Mimica

University of Zagreb

Oliver Kozumplik

Klinika za psihijatriju Vrapče

Suzana Uzun

University of Zagreb

Dunja Degmečić

University Hospital Centre Zagreb

Dubravka Kalinić

University of Zagreb

Oliver Koić

University of Osijek

Vesna Pereković

Katarina Dodig‐Ćurković

University of Osijek

Davor Laufer

University of Osijek

Cooperative Institutions

University of Osijek

Klinički bolnički centar Osijek

University Hospital Centre Zagreb

Psychiatric Hospital Sveti Ivan

Klinika za psihijatriju Vrapče

University of Zagreb

University of Split

University Psychiatric Hospital

Ministry of Health

Klinički Bolnički Centar Split

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PARADOXAL REACTIONS TO BENZODIAZEPINES

Psychiatria Danubina (2009)

Dunja Degmečić Ivan Požgain Pavo Filaković Katarina Dodig‐Ćurković

Paradoxal reactions to benzodiazepines may be presented in different ways. In some persons, primarily older persons and children, especilally with coexisting somatic disorders, paradoxal reactions may be manifested as logoroic speech, unapropriate social behaviour, and psychomotor agitation. Although benzodiazepines lower levels of agression, few studies described that in some persons levels of agression get higher with use of benzodiazepines. From our clinical practice we will present the patient who deveoped changed 'uninhibited' behavour after use of alprazolam perorally. Patient K.M. in age of 41 years, married, with one child, works as a clark at office. He denied psychiatric disoreders in his relatives, and also he denied any somatic disorders. Patient came to the psychiatrist after he had troubles at his job, he was acused of something he didn't do. He desided to ask help after few weeks of troubles in functioning, he couldn't sleep, he was anxious, emotionally instable, he couldn't controll crying, his thougts were peocupaied with problems at job, his communication with his family was disturbed. His wife told him to seek for help. He was diagnsed as Acute reaction to stress, and prescribed alprazolam in small dose od 2x0,25 mg per day. After two weeks he came to controll and described the same symptoms, so his therapy was corrected to alprazolam 3x0,5mg per day. After ten days he came with his wife to controll exam. He was different person as his wife described him. He was angry all the time, he was verbally agressive to family members as well as to their friends. He described that he couldn't keep his mouth quiet, everything that bothered him he yelled about it. He went to his job and was verbally agressive and abusive to his working collleagues. Patient described very high levels of agitation, he couldn't be still at one place. Before his wife described him as very quiet and nice person, he never raised his voice, and always found peacefull solutions to every problem. We told him to stop taking the medication, and he came to controll exam after one week. Two days after the last medication his agression dissapeared, he was ashamed of his behaviour. But he told that lot's of things he sad last few weeks he wanted to say for many years before, but he was too anxious and affraid to do so. Therefore, in this case report it is unclear what really happened, was that desinhibition or not?

Alprazolam

Wife

Psychomotor agitation

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P.3.a.035 Psychoeducation and compliance in the treatment of the patients with schizophrenia

European Neuropsychopharmacology (2006)

Dunja Degmečić Ivan Požgain Mia Grgić Pavo Filaković

Psychoeducation

Chi-square test

10.1016/s0924-977x(06)70464-3

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Kako odabrati optimalnu terapiju za depresivnog bolesnika

Medicus (2017)

Ivan Požgain

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Doprinos terapijske zajednice liječenju posttraumatskog stresnog poremećaja

Socijalna psihijatrija (2004)

Ivan Požgain Dunja Degmečić Vesna Pereković Nada Blagojević-Damašek

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Glazba kao terapija

International Review of the Aesthetics and Sociology of Music (2005)

Dunja Degmečić Ivan Požgain Pavo Filaković

Resume The article focuses on music as a therapeutic option in psychiatry. In the first part of the article the authors have given a review of various comprehensions and definitions of music itself, as well as the effect of music on the mind. The idea of music as a healing influence which could influence health and behaviour is at least as old as the writings of Aristotle and Plato. Today, music therapy is a well-established allied segment of the health profession, similar to occupational therapy and physical therapy. It consists of using music therapeutically to address physical, psychological, cognitive, behavioural and social functioning. The music therapy experience is related to art and everyday experiences in many different ways. In other parts of the article, the authors have tried to show the importance of rhythm through life, as well as to show the functions of music therapy, and the favourable experiences that they have had with their patients who had music therapy as a therapeutic option.

Music Therapy

Everyday Life

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The influence of risperidone on cognitive functions in schizophrenia.

PubMed (2003)

Jelena Barkić Pavo Filaković Ljiljana Radanović-Grgurić Oliver Koić Davor Laufer

Introduction of the antipsychotics of the second generation (SGA) into the therapy of schizophrenia roused expectations that, finally, the cognitive dysfunction in schizophrenia could be eliminated by psychopharmacological therapy. The purpose of the study was to verify the effect of atypical antipsychotic risperidone on cognitive functions in schizophrenic patients. The study was carried out upon 48 male schizophrenic patients aged 21-47 years who were switched from the antipsychotics of the first generation (FGA) to the antipsychotic risperidone, due to intolerance, during the treatment. Intelligence, abstract and concrete thinking and mental speed, attention, and short-term non-verbal memory prior to the switch, one month after the switch, and three months after the switch to risperidone, were evaluated. One month after the switch the number of subjects with severe impairment of intellectual abilities decreased significantly from 62% to 15% and after three months the number was even lower-8%. The impairment of concrete and abstract thinking and mental speed also showed the same tendencies of decrease. The improvement of the cognitive functioning after the switch from the antipsychotics of the first generation to the antipsychotic risperidone is explained by removal of the antipsychotics of the first generation from the therapy and the consequential disinhibition of secondary cognitive impairments and by decreased average dose of anticholinergic and decreased number of patients who need anticholinergic therapy beside risperidone. The possibility of clear pro-cognitive effect of risperidone is suggested and its verification is proposed with strict control of other factors that improve cognitive functioning of schizophrenic patients during the treatment.

Cognitive remediation therapy

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THE USE OF PSYCHOPHARMACEUTICALS IN PREGNANCY

Socijalna psihijatrija (2009)

Oliver Koić Pavo Filaković Ljiljana Radanović-Grgurić Davor Laufer Ivan Požgain

Za klinicara koji lijeci psihicki poremecaj, trudnoca pacijentice je poseban problem. Tragedija izazvana talidomidom ispravila je duboko ukorijenjenu zabludu o placenti kao ucinkovitoj zastiti od stetnih tvari. S obzirom da ne postoje dobro kontrolirana, prospektivna istraživanja o utjecaju lijekova na fetus i kasniji razvoj djeteta, a sto ce iz poznatih razloga i dalje ostati takvim, klinicari ce i dalje biti nesigurni u procjenama mogucih rizika. Na temelju toga su autori u ovome radu prikazali dosadasnja saznanja o primjeni benzodiazepina, antidepresiva, antipsihotika i afektivnih stabilizatora tijekom trudnoce. Rizike i koristi primjene lijeka mora se procijeniti u svakom pojedinom slucaju, a lijecenje se mora ograniciti na one slucajeve u kojima je rizik nelijecenog psihickog poremecaja za majku i fetus veci od rizika primjene lijeka.

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Posttraumatski stresni poremećaj u hrvatskih vojnika na istočnoslavonskom bojištu

Medicinski vjesnik (1992)

Ivan Požgain Pavo Filaković Vesna Pereković

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IMPACT OF METEOROLOGICAL FACTORS ON SUICIDE ATTEMPTS AND COMPLETED SUICIDES IN CROATIA, OSIJEK - BARANJA COUNTY

→ Petra Boris Dumenčić Jasmina Rajc Ksenija Marjanović Ivan Požgain

Background: Significant changes in the values of temperature, pressure, humidity and cloud cover can participate in the human behaviour including the mood disorders (especially depression and bipolar disorders) which can trigger suicidal ideas or their realization. The aim of this study is to estimate the connection between the aforesaid weather changes and a committed suicide alongwith the suicide attempts.Subjects and methods: We conducted a retrospective study in Osijek - Baranja County in the period from 2000 to 2011.Meteorological, demographic and epidemiological analysis was performed on 569 suicides and 478 suicide attempts (total of 1047 events). We analyzed the values of the above-mentioned meteorological parameters at the exact time when the event had happened, as well as three days before the event and one day after the event, comparing it with the monthly mean values.Results: The results showed that the changes of temperature and pressure were significantly related with the suicides i.e. suicide attempts in general, while by separating genders, a connection with all examined meteorological factors was found by woman whereas men expressed significance only in the matter of temperature changes.Conclusions: Despite the fact that suicidality is caused by numerous factors, this study confirms that a sudden change of weather in the days preceding the suicide can be a trigger to suicidal behaviour. The study also suggests that in the matter of suicidal behaviour, female population is more susceptible to sudden weather changes.

Depression

Suicidal Behavior

10.31219/osf.io/a4g5m

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Emotional profile and risk behaviours among tattooed and non-tattooed students.

DOAJ (DOAJ: Directory of Open Access Journals) (2015)

Matea Zrno Maja Frencl Dunja Degmečić Ivan Požgain

To determine differences in emotional profile and frequencies of certain risk behaviours between tattooed and non-tattooed students.One hundred students fulfilled personality assessment (trust, timid, depressive, distrust, aggressive, gregarious, controlled, uncontrolled) and questionnaire of socio-demographic data that also included some questions about possession of tattoo (time, place, motive) and about certain risk behaviours (court punishment, consummation of alcohol, psychoactive substances and cigarettes).The total number of 35 (out of 100) students had a tattoo, and 67 wished to have a tattoo. There was no statistically significant difference in emotional profile between tattooed and non-tattooed individuals, yet the differences were detected when the group of subjects who wanted a tattoo and those who did not want a tattoo were compared. Higher result on the aggression scale of and lower on control scale was gained by those with the wish for tattooing. Students with bigger tattoos (23) showed higher score on depression scale. Students in the tattooed group more frequently abused drugs and committed traffic offences compared to the students in non-tattooed group.Results of this research as well as previous research show that the presence of a tattoo could be a rough indicator for possible emotional problems and risk behaviour, which could have significant implications in preventing these behaviours. Future studies are required on a larger and more representative sample as well as to clarify why young people decide to be tattooed.

Depression

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