Maria Luisa Pontecorvo

Università Cattolica del Sacro Cuore

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Giampaolo Niccoli

University of Parma

Cristina Spaziani

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Marcello Marino

Azienda Ospedaliera Ospedale Maggiore

Marco Bacà

Ospedale generale di zona San Camillo Treviso

Filippo Crea

Agostino Gemelli University Polyclinic

Nicola Cosentino

AstraZeneca (Italy)

Miriam Shanks

University of Alberta

Eduardo Bossone

University of Naples Federico II

Diego Sangiorgi

Maria Cecilia Hospital

Alessandro Martinoni

Aziende Socio Sanitarie Territoriale Ovest Milanese

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Istituti di Ricovero e Cura a Carattere Scientifico

University of Milan

IRCCS Policlinico San Donato

Università Cattolica del Sacro Cuore

Azienda Ospedaliera Ospedale Civile di Legnano

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda

Centro Cardiologico Monzino

Istituti Ospitalieri di Cremona

Agostino Gemelli University Polyclinic

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

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The American Journal of Cardiology (2010)

Giampaolo Niccoli Cristina Spaziani Marcello Marino Maria Luisa Pontecorvo Miriam Shanks

10.1016/s0002-9149(10)00427-3

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Effect of Chronic Aspirin Therapy on Angiographic Thrombotic Burden in Patients Admitted for a First ST-Elevation Myocardial Infarction

The American Journal of Cardiology (2010)

Giampaolo Niccoli Cristina Spaziani Marcello Marino Maria Luisa Pontecorvo Nicola Cosentino

10.1016/j.amjcard.2009.10.040

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[Myocardial no-reflow phenomenon: recent knowledges].

Maria Luisa Pontecorvo Cristina Spaziani Rocco A. Montone Nicola Cosentino Silvia Minelli

Early revascularization of the infarct-related artery by primary percutaneous coronary intervention (PPCI) has become the gold standard therapy in ST-segment elevation myocardial infarction (STEMI). However, in a number of patient undergoing PPCI, epicardial coronary artery reperfusion: does not translate into myocardial reperfusion: a phenomenon called as no-reflow. The no-reflow phenomenon has a multifactorial pathogenesis, including: distal embolization, ischemia-reperfusion injury, and individual predisposition of coronary microcirculation to injury. Angiographic and electrocardiographic indexes may be used for the diagnosis. Also, lack of ST-segment elevation resolution is considered an established marker of no-reflow. Importantly, the no-reflow phenomenon provides prognostic information in STEMI patients because it is associated with low ventricular ejection fraction, adverse left ventricular remodelling and mortality at follow-up. Various mechanical devices and pharmacological approaches have been proposed to prevent and to treat the phenomenon: the assessment of mechanisms of no-reflow might guide the development of personalized form of treatment. This paper will be focused on the postulated mechanisms of the phenomenon, modalities for the diagnosis, and the main treatment options.

No reflow phenomenon

10.1701/552.6589

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Spontaneous coronary dissection as cause of recurring myocardial infarction

Journal of Cardiovascular Medicine (2010)

Ilaria Dato Giampaolo Niccoli Marco Bacà Maria Luisa Pontecorvo Filippo Crea

Dato, Ilaria; Niccoli, Giampaolo; Bacà, Marco; Pontecorvo, Maria L; Crea, Filippo Author Information

Artery dissection

10.2459/jcm.0b013e32833a085d

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Citations (2)