Jihui Tang

Anhui Medical University

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i-10 index

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Rongfeng Hu

Anhui University of Traditional Chinese Medicine

Jianwei Bao

Anhui Medical University

Qianqian Zhang

Anhui Medical University

Tijie Duan

Anhui Medical University

Siyu Guan

Jianghan University

Tori Czech

Northeast Ohio Medical University

Minxing Hu

Anhui Medical University

Feihu Chen

Anhui Medical University

Lei Ye

Wenzhou Medical University

Jue Song

Ministry of Education of the People's Republic of China

Cooperative Institutions

Anhui Medical University

Ministry of Education of the People's Republic of China

Sun Yat-sen University

Chinese Academy of Sciences

Anhui University of Traditional Chinese Medicine

Fudan University

Chinese Academy of Medical Sciences & Peking Union Medical College

Zhejiang University

University of Chinese Academy of Sciences

First Affiliated Hospital of Anhui Medical University

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In vivo pharmacokinetics and biodistribution of novel all-trans retinoic acid derivative-loaded, folate-modified poly ( l -amino acid) micelles

Journal of Drug Delivery Science and Technology (2017)

Wenxiu Hong Rongfeng Hu Xuechao Huang Xiaoqian Lu Tori Czech

Biodistribution

10.1016/j.jddst.2017.09.007

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Citations (3)

In vivo pharmacokinetics, biodistribution and antitumor effect of amphiphilic poly(l-amino acids) micelles loaded with a novel all-trans retinoic acid derivative

European Journal of Pharmaceutical Sciences (2013)

Jihui Tang Xin-Qun Wang Ting Wang Feihu Chen Jianping Zhou

Biodistribution

10.1016/j.ejps.2013.09.016

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Citations (7)

The determination of the viability of Schistosomal eggs by a novel technique: electrorotation.

PubMed (2013)

L. Liu Jihui Tang F Zhang X Wang Bin Xu

Human schistosomiasis is widespread in tropical and subtropical environments. In this study, a novel open cell with liquid medium perfusion system for electrorotation measurement to detect the viability of schistosomal eggs is proposed. With no solid top or bottom surface, the liquid medium perfusion system solves some of the problems of conventional electrorotation testing systems. This kind of open cell successfully detect schistosome egg viability, most prominently, there can be no adhesion or friction of eggs on the surface to encumber their rotation. This newly proposed system can be used to test more types of biological particles compared to a conventional system used in electrorotation measurement, providing more exact results. The new system can be used for rapid analysis of various biological particles in water, which will be potentially significant to public health.

Viability assay

Liquid medium

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Citations (1)

Research Status and Application of AirSource Heat Pump Technology

Thermal Science and Engineering (2018)

Hongtao Meng Jihui Tang Haifeng Huang

Abstract: With the improvement of people's living standards, water heaters almost into the various households. In the energy-saving emission reduction has become the trend of the times today, saving energy and reducing carbon emissions is the most fashionable way of life. Air source heat pump water heaters are increasingly being used in people's lives. It is well known that it has many advantages, safety, energy saving, comfort, environmental protection, but there are some factors that affect its development and promotion. This paper mainly discusses the development history of air source heat pump technology at home and abroad, working principle, working flow, turbo technology at present stage, efficient heat exchange, and the research status of air source heat pump technology, such as new type refrigerant and dual frequency compression frequency conversion, then it discusses the application of air source heat pump technology, has the advantage, and finally discusses its application and the existence of two major problems and suggestions for improvement. Key words:air source heat pump; water heater; energy saving and emission reduction; research status

Coefficient of performance

10.24294/tse.v1i1.363

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Citations (0)

Study on the absorption kinetics of benazepril hydrochloride

Chinese Journal of Hospital Pharmacy (2006)

Rongfeng Hu Jia-bi Zhu Jihui Tang Zhan You-qun Shuang Wang

OBJECTIVE To explore the absorption mechanism of benazepril hydrochloride from various intestinal segments.METHODS The absorption kinetics and permeability rate constants(Ka) were investigated by the in situ perfusing method in rats.The absorption mechanism of benazepril hydrochloride was studied at different concentrations.RESULTS It was shown that the small intestine was the best absorption segment.The permeability rate constants of benazepril hydrochloride were(0.789),(0.810),(0.766) h ~(-1) respectively at different concentration such as low,medium,high concentration.No saturation phenomenon occurred and at the same time,Ka was kept unchanged.CONCLUSION The absorption of benazepril hydrochloride is in conformity the passive transport mechanism and first order kinetics.

Benazepril

Absorption rate

Hydrochloride

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Mild hypothermia reduces lipopolysaccharide-induced microglial activation via down-regulation of Tent5c

Biochemical and Biophysical Research Communications (2024)

Wen‐xian Ma Shao-wen Wang Qian-wen Fan Yueyue Wang Chao-qun Chu

Proinflammatory cytokine

10.1016/j.bbrc.2024.149767

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The role of the cell cycle in the cellular uptake of folate-modified poly(l-amino acid) micelles in a cell population

Nanoscale (2015)

Jihui Tang Ziwei Liu Fenqi Ji Yao Li Junjie Liu

Nanoparticles are widely recognized as a vehicle for tumor-targeted therapies.

10.1039/c5nr03850b

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Citations (18)

The Fate of Nanoparticles In Vivo and the Strategy of Designing Stealth Nanoparticle for Drug Delivery

Current Drug Targets (2021)

Jianwei Bao Qianqian Zhang Tijie Duan Rongfeng Hu Jihui Tang

Nano-drug delivery systems (Nano-DDS) offer powerful advantages in drug delivery and targeted therapy for diseases. Compared to the traditional drug formulations, Nano-DDS can increase solubility, biocompatibility, and reduce off-targeted side effects of free drugs. However, they still have some disadvantages that pose a limitation in reaching their full potential in clinical use. Protein adsorption in blood, activation of the complement system, and subsequent sequestration by the mononuclear phagocyte system (MPS) consequently result in nanoparticles (NPs) to be rapidly cleared from circulation. Therefore, NPs have low drug delivery efficiency. So, it is important to develop stealth NPs for reducing bio-nano interaction. In this review, we first conclude the interaction between NPs and biological environments, such as blood proteins and MPS, and factors influencing each other. Next, we will summarize the new strategies to reduce NPs protein adsorption and uptake by the MPS based on current knowledge of the bio-nano interaction. Further directions will also be highlighted for the development of biomimetic stealth nano-delivery systems by combining targeted strategies for a better therapeutic effect.

Mononuclear phagocyte system

Clearance

Biocompatibility

Targeted drug delivery

10.2174/1389450122666210118105122

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Citations (19)

Synthesis and Characterization of 3D CuO Hierarchical Structure by Nanoplates Two-Step Self-Assembly

Asian Journal of Chemistry (2013)

Xiaoyan Liu Hongmei Zang Jue Song Jihui Tang Yitai Qian

Characterization

10.14233/ajchem.2014.15348