Ana Lia Anbinder

Universidade Estadual Paulista (Unesp)

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i-10 index

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Yasmin Rodarte Carvalho

Universidade Estadual Paulista (Unesp)

Estela Kaminagakura

Universidade Estadual Paulista (Unesp)

Renata Mendonça Moraes

Universidade Estadual Paulista (Unesp)

Janete Días Almeida

Universidade Estadual Paulista (Unesp)

Ana Sueli Rodrigues Cavalcante

Universidade Estadual Paulista (Unesp)

Jaqueline Lemes Ribeiro

Universidade Estadual Paulista (Unesp)

Noala Vicensoto Moreira Milhan

Universidade Estadual Paulista (Unesp)

Juliana Campos Junqueira

Universidade Estadual Paulista (Unesp)

Rosilene Fernandes da Rocha

Universidade Estadual Paulista (Unesp)

Mônica Ghislaine Oliveira Alves

Universidade Estadual Paulista (Unesp)

Cooperative Institutions

Universidade Estadual Paulista (Unesp)

159

Universidade de São Paulo

Universidade Estadual de Campinas (UNICAMP)

Fundação Faculdade de Odontologia

Universidade de Taubaté

Universidade Federal de Minas Gerais

Universidade Federal do Rio de Janeiro

Institute of Science and Technology

Universidade Federal do Rio Grande do Norte

Universidade do Vale do Paraíba

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The Oral and Maxillofacial Pathologist: The Dentist Behind the Microscope

Frontiers for Young Minds (2024)

Luisa Souza Battistelli Thaís Aguiar Santos Ana Lia Anbinder

Lots of people think that all dentists use little mirrors and loud tools like dental drills, but there is a type of dentist who does not need these things: the oral and maxillofacial pathologist. Can you believe that oral pathologists do not actually treat the teeth or even meet the patient? The oral pathologist receives a tiny piece of tissue from the patient, usually obtained through a small surgery called a biopsy. Then, a super tiny slice of that tissue is prepared and placed on a glass slide, and the oral pathologist looks at it through a microscope to figure out what disease the patient might have. This information is important to give the patient the right treatment. Do you want to learn more about this process and about the healthcare professional who does not meet the patient face-to-face? Keep reading to find out all these answers and more!

Hard tissue

10.3389/frym.2024.1389097

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Citations (0)

UNCOMMON VARIANT OF A WELL-KNOWN LESION: DIAGNOSTIC DISCUSSION

JORDI - Journal of Oral Diagnosis (2018)

Ana Lia Anbinder Milagros del Valle El Abras Ankha Felix de Castro Jaqueline Lemes Ribeiro Yasmin Rodarte Carvalho

10.5935/2525-5711.20170072

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COLLAGEN-RICH MANDIBULAR LESION: CASE REPORT AND DIFFERENTIAL DIAGNOSIS

JORDI - Journal of Oral Diagnosis (2018)

Ana Lia Anbinder Ana Sueli Rodrigues Cavalcante Victor Costa Fernanda Vieira Amorim da Costa Yasmin Rodarte Carvalho

10.5935/2525-5711.20170095

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Oral pyogenic granuloma: An 18‐year retrospective clinicopathological and immunohistochemical study

Journal of Cutaneous Pathology (2021)

Jaqueline Lemes Ribeiro Renata Mendonça Moraes BRUNA FERNANDES DO CARMO CARVALHO Anderson de Oliveira Nascimento Noala Vicensoto Moreira Milhan

Abstract Background Pyogenic granuloma (PG) is a lesion characterized by the proliferation of blood vessels, commonly affecting the skin and the mouth. We aimed to compare clinical, microscopic, and immunohistochemical features of the two types of oral PG: lobular capillary hemangioma (LCH) and non‐LCH (NLCH). Methods Epidemiological and clinical data from 2000 to 2018 were collected from the archives of our institution, and histopathological sections of PG were reviewed. Immunohistochemical analyses (CD34, D2‐40, SMA, mast cell, and Ki‐67) were performed in 34 cases. Results Sixty‐two LCH and 107 non‐LCH samples were included. The mean (±SD) age of the patients was 38.59 ± 16.96 years; 55.62% were female; 39.64% of cases occurred in the gingiva, 44% of the nodules were pedunculated, and 13.02% of patients reported a history of trauma. NLCH was more prevalent among older patients than LCH. The most prevalent site of LCH was the lips, while NLCH occurred more in the gingiva ( P < 0.05). Epithelial atrophy, microvessels, SMA‐positive areas, and Ki‐67‐positive nuclei were more prevalent in LCH ( P < 0.05). Conclusions PG accounted for 2.25% of lesions archived in the pathology service and most cases were NLCH. LCH and NLCH exhibited clinicopathological differences in terms of age, site, epithelial atrophy, vascularization, and proliferation rate.

Pyogenic granuloma

Capillary hemangioma

10.1111/cup.13970

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Citations (10)

Oral Syphilis: Case Report of a Re-Emerging Disease

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology (2018)

Jaqueline Lemes Ribeiro Adriana Mota Delgado Noala Vicensoto Moreira Milhan Yasmin Rodarte Carvalho Ana Lia Anbinder

Lamina propria

10.1016/j.oooo.2018.02.183

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Citations (1)

LOCALIZED JUVENILE SPONGIOTIC GINGIVAL HYPERPLASIA: REPORT OF TWO CASES.

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology (2024)

Yuri Cavalcante SANTOS Jaqueline Lemes Ribeiro Elis Andrade de Lima Zutin Márcia Gimenes Américo Lígia Ângelo Tavares Schwarzmeier

10.1016/j.oooo.2023.12.086

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Stromal Myofibroblasts in Correlation With Inflammation and Impacted Tooth in Odontogenic Cysts: An Immunohistochemical Comparative Study

Research Square (Research Square) (2023)

Karina Helen Martins CAMILA DE OLIVEIRA BARBEIRO Roberto Henrique Barbeiro Ana Lia Anbinder R. Guardia

Abstract Aim Stromal myofibroblasts may act favoring growth and progression of odontogenic lesions, notably odontogenic keratocyst (OKC). While little explored the associated inflammation, it has been shown that OKC associated with an impacted tooth has a tendency toward rapid growth. Whether this finding is associated with the differential expression of myofibroblast immunomarkers, is unknown. Materials and methods Thirteen cases of each, pericoronal follicle (PF), inflamed dentigerous cyst (iDC), noninflamed DC (nDC), OKC associated with (OKC-A) or not associated (OKC-N) with impacted tooth, were evaluated through vimentin, α-SMA, calponin and h-caldesmon immunomarkers The data obtained were analyzed using the Shapiro-Wilk, Kruskal-Wallis and Dwass-Steel-Critchlow-Fligner Multiple Comparisons tests, with p < 0.05 being considered statistically significant. Results All cases were vimentin positive, with few cases exhibiting mild expression. All PFs were α-SMA negative. OKCs showed significant higher expression of α-SMA than DCs (p < 0.05). With similar expression between DC groups, the α-SMA expression was higher in OKC-A than OKC-N (p = 0.882). Also, the mean age of OKC-A was significantly lower than OKC-N patients. Only 4 cases (1 iDC, 3 OKC-N) showed mild expression of calponin. All cases were h-caldesmon negative. Conclusions Our results suggest lack of myofibroblastic differentiation in PFs. Inflammation does not seem to influence the myofibroblast population in DCs. Although not significant, a higher expression of α-SMA can explain the clinicopathological features of OKC-A patients. Calponin seems not to be a reliable marker for myofibroblasts in these cases. Clinical relevance Lack of myofibroblastic differentiation seems to be consistent with the nature and function of PF. OKC (still, OKC-A than OKC-N) presents higher α-SMA expression than DC, which can help to explain its distinctive growth potentials.

Keratocyst

Myofibroblast

Calponin

Caldesmon

10.21203/rs.3.rs-3179661/v1

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Fluoxetine Inhibits Inflammatory Response and Bone Loss in a Rat Model of Ligature‐Induced Periodontitis

Journal of Periodontology (2011)

Luciana Salles Branco-de-Almeida Gilson César Nobre Franco Myrella Léssio Castro Juliana Guimarães dos Santos Ana Lia Anbinder

Background: Fluoxetine, a selective serotonin reuptake inhibitor, has been found recently to possess anti‐inflammatory properties. The present study investigates the effects of fluoxetine on inflammatory tissue destruction in a rat model of ligature‐induced periodontal disease. Methods: Thirty male Wistar rats were randomly assigned into three groups (n = 10 animals per group): 1) control rats (without ligature); 2) rats with ligature + placebo (saline; oral gavage); and 3) rats with ligature + fluoxetine (20 mg/kg/day in saline; oral gavage). Histologic analyses were performed on the furcation region and mesial aspect of mandibular first molars of rats sacrificed at 15 days after ligature‐induced periodontal disease. Reverse transcription‐polymerase chain reaction and zymography were performed to analyze the mRNA expression of interleukin (IL)‐1β, cyclooxygenase (COX)‐2, matrix metalloproteinase (MMP)‐9 and inducible nitric oxide synthase and the MMP‐9 activity, respectively, in gingival tissues samples. Results: Compared to the ligature + placebo group, alveolar bone loss was reduced in the fluoxetine group ( P <0.05), and the amount of collagen fibers in the gingival tissue was maintained. Moreover, in gingival tissue sampled 3 days after ligature attachment, fluoxetine administration reduced IL‐1β and COX‐2 mRNA expression. Fluoxetine downregulated MMP‐9 activity, without affecting MMP‐9 mRNA expression induced by ligature, compared to the ligature + placebo group ( P <0.05). These data suggest that fluoxetine suppressed proinflammatory responses, as well as proteolytic enzyme activity, induced by ligature. Conclusion: In the present study, fluoxetine suppresses the inflammatory response and protects against periodontal bone resorption and destruction of collagen fibers, suggesting that fluoxetine can constitute a promising therapeutic approach for periodontal diseases.

Ligature

Inflammatory response

Rat model

10.1902/jop.2011.110370

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Citations (70)

Low-Grade Central Osteosarcoma in Mandible: Case Report

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology (2014)

Renata Rodrigues Acay Walter Niccoli‐Filho Vivian Narana Ribeiro El Achkar Gabriela de Morais Gouvêa Lima Estela Kaminagakura

Osteoid

Mandible (arthropod mouthpart)

Pleomorphism (cytology)

10.1016/j.oooo.2013.12.103

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Congenital ranula: a case report.

PubMed (2009)

Ana Sueli Rodrigues Cavalcante Luiz Eduardo Blumer Rosa Nívea Cristina Sena Costa Márcia Hatakeyama Ana Lia Anbinder

The purpose of this study was to report a case of bilateral swelling on the floor of the mouth of a 7-month-old patient. The lesion was congenital and had started to cause feeding problems. After the clinical diagnosis of ranula was made, the lesion was marsupialized. The obtained specimen was submitted for histopathological examination, which revealed an epithelial-lined cystic lesion. These results led to the final diagnosis of mucus retention cyst. After an 8-year follow-up period, the patient is in good general health with no recurrences.

Ranula

Histopathological examination

Floor of mouth

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Citations (8)