Stewart J. Friedman

Sidney & Lois Eskenazi Hospital

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

W. George Bingham

Doctors Hospital

Robert Ruffolo

Research Triangle Park Foundation

Jan Knofel

The Ohio State University

David Yashon

The Ohio State University

Harold Goldman

University of Delaware

William E. Hunt

Lawrence Livermore National Laboratory

Sharon Murphy

Wayne State University

Joseph H. Goodman

The Ohio State University

David J. Doedens

Indiana University – Purdue University Indianapolis

George R. Aronoff

Colorado Kidney Care

Cooperative Institutions

The Ohio State University

Neurological Surgery

Ohio State University Hospital

Indiana University School of Medicine

Indiana University – Purdue University Indianapolis

Walter Reed Army Institute of Research

Wayne State University

Sidney & Lois Eskenazi Hospital

Doctors Hospital

University of California, San Francisco

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Blood flow in normal and injured monkey spinal cord

Journal of neurosurgery (1975)

W. George Bingham Harold Goldman Stewart J. Friedman Sharon Murphy David Yashon

✓ The authors used indicator fractionation techniques to determine blood flow in normal and bluntly traumatized spinal cords of Macaca rhesus monkeys. Normal flow rates were determined for several levels of spinal cord as well as differential values for white and gray matter from representative areas. Flow rates in traumatized tissue, obtained at several different time intervals up to 4 hours after injury, demonstrated marked differences in regional perfusion of the white matter and gray matter after trauma. Gray matter perfusion was nearly obliterated while white matter blood flow persisted and in fact was higher than uninjured controls. The findings do not support the concept of ischemia as a factor in white matter failure. If toxic pathobiochemical alterations are induced by trauma, it may be possible to reverse these changes by exploiting the preserved white matter blood flow for chemotherapeutic intervention.

Grey matter

10.3171/jns.1975.43.2.0162

Cite

Citations (111)

Norepinephrine and dopamine levels in normal dog and monkey spinal cord

Life Sciences (1975)

W. George Bingham Robert Ruffolo Joseph H. Goodman Jan Knofel Stewart J. Friedman

Lumbosacral joint

10.1016/0024-3205(75)90069-7

Cite

Citations (13)

Catecholamine levels in the injured spinal cord of monkeys

Journal of neurosurgery (1975)

W. George Bingham Robert Ruffolo Stewart J. Friedman

The authors report a study of catecholamine levels in the spinal cords of monkeys following a 300 gm-cm blow to the midthoracic spinal cord. There was a progressive decrease in norepinephrine (NE) activity as a first-order process with a half-life of 6.4 hours. The NE activity in injured tissue never exceeded control levels, which remained unchanged both above and below the injured segment. Dopamine activity remained unchanged in the injured tissue as well as in control segments above and below the area of trauma for the first hour.

10.3171/jns.1975.42.2.0174

Cite

Citations (44)

Case Report Increased serum iodide concentration from iodine absorption through wounds treated topically with povidone-iodine

The American Journal of the Medical Sciences (1980)

George R. Aronoff Stewart J. Friedman David J. Doedens Kevin J. Lavelle

Serum concentration

10.1097/00000441-198005000-00007

Cite

Citations (40)