Jennifer M. Grants

Canada's Michael Smith Genome Sciences Centre

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Co-Authors

Aly Karsan

University of British Columbia

Martín E. Fernández-Zapico

Mayo Clinic

Eric B. Haura

Moffitt Cancer Center

Guolin Zhang

Ball State University

Christy Finke

Mayo Clinic in Arizona

Mrinal M. Patnaik

Mayo Clinic in Arizona

Jeffrey E. Lancet

Moffitt Cancer Center

Christopher T. Letson

Washington University in St. Louis

Luciana L. Almada

Novel (United States)

Rami S. Komrokji

Moffitt Cancer Center

Cooperative Institutions

University of British Columbia

BC Cancer Agency

Canada's Michael Smith Genome Sciences Centre

Moffitt Cancer Center

British Columbia Children's Hospital

Spinal Cord Injury BC

Terry Fox Research Institute

Simon Fraser University

Child and Family Research Institute

Mayo Clinic

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Supplementary Figure S3 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Supplemental Figure 3 shows endogenous PIM1 levels in SKM1 WT and overexpressing cells and BETi/PIMi sensitivity correlation in PIM1 overexpressing cells.

PIM1

10.1158/1078-0432.23561026

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Supplementary Figure S7 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Supplemental Figure 7 shows clonogenicity data associated with 6A broken down by patient sample and a non-transplanted control sample stained with CD45 corresponding to Figure 6E.

Sample (material)

10.1158/1078-0432.23561014.v1

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Supplementary Figure S4 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Supplemental Figure 4 contains data related to miR-33a regulation in BETi treated cells.

10.1158/1078-0432.23561023

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Supplementary Data S2 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Raw RNAseq data corresponding to Figures 2C, 4D and Supplemental Figure 2B

10.1158/1078-0432.23814923

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Supplementary Table S2 from Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

References used for filtering hits from drug screen

Table (database)

10.1158/1078-0432.27031879

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Supplementary Data S2 from Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Raw RNAseq data corresponding to Figures 2C, 4D and Supplemental Figure 2B

10.1158/1078-0432.27031903

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Supplementary Figure S3 from Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Supplemental Figure 3 shows endogenous PIM1 levels in SKM1 WT and overexpressing cells and BETi/PIMi sensitivity correlation in PIM1 overexpressing cells.

10.1158/1078-0432.27031897

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Supplementary Table S2 from Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

References used for filtering hits from drug screen

10.1158/1078-0432.27031879.v1

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Supplementary Table S2 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

References used for filtering hits from drug screen

10.1158/1078-0432.23814896.v1

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Supplementary Figure S2 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML

Christopher T. Letson Maria E. Balasis Hannah Newman Moritz Binder Alexis Vedder

Supplemental Figure 2 shows PIM1 levels over time, GSEA data demonstrating increased PIM expression and Western blot images of PIM isoforms in all other cell lines

10.1158/1078-0432.23814917.v1

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