Mercedes Weissenbacher

Academia Nacional de Medicina

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i-10 index

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María Mercedes Ávila

University of Oxford

Miguel A. Calello

University of Buenos Aires

Rubén P. Laguens

Favaloro University

M. J. Frigerio

University of Buenos Aires

M Boxaca

University of Buenos Aires

Silvia M. Montano

Azienda Ospedaliero-Universitaria Careggi

Diana Rossi

University of Buenos Aires

Guadalupe Carballal

Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno

O Libonatti

University of Buenos Aires

Sergio R. Samoilovich

Asociación Psicoanalítica de Buenos Aires

Cooperative Institutions

University of Buenos Aires

119

Consejo Nacional de Investigaciones Científicas y Técnicas

Henry M. Jackson Foundation

Administración Nacional de Laboratorios e Institutos de Salud

Walter Reed Army Institute of Research

Naval Medical Research Command

National Institutes of Health

Karolinska Institutet

Naval Medical Research Unit Six

Centers for Disease Control and Prevention

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Author Index, Vol. 20, 1983

Intervirology (1983)

George Klein Corinna Quan Frances W. Doane Ye Zeng J.M. Zhong

10.1159/000149396

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Nasal and intrathalamic inoculations of primates with Tacaribe virus: protection against Argentine hemorrhagic fever and absence of neurovirulence.

PubMed (1984)

Sergio R. Samoilovich Jorge Pecci Saavedra M. J. Frigerio Mercedes Weissenbacher

Callithrix jacchus marmosets were inoculated by different routes with two stocks of Tacaribe virus, one from suckling mouse brain and another from human diploid MRC5 cells. All 12 primates inoculated by nasal route developed neutralizing serum antibodies without any clinical signs. All 6 primates receiving the mouse brain-Tacaribe virus were protected against lethal challenge with pathogenic XJ strain of Junin virus, while protection was also conferred in 4 out of 6 primates receiving the diploid cell-Tacaribe virus stock. Intramuscular (i.m.) inoculation also elicited antibodies and conferred protection to 4 primates receiving the diploid cell-virus stock. Intrathalamic (i.t.) inoculation of mouse brain-virus stock caused no clinical signs or histopathologic changes in groups of 3 primates each examined on days 33 and 90 post-infection (p.i.). All primates developed antibody response, but no virus could be detected in their brain. Thus, Tacaribe virus proved harmless and immunogenic in Callithrix jacchus and protected most marmosets against challenge with the lethal XJ strain of Junin virus.

Junin virus

Arenavirus

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Citations (17)

[Antigenic variants of the respiratory syncytial virus in Argentina and Uruguay].

PubMed (1988)

Salomón He Russi Jc M Grandien Claes Örvell Avila Mm

Etiology

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Citations (2)

Tendencias de la epidemia del VIH/SIDA en América latina

Publicación oficial de la Sociedad Española Interdisciplinaria del SIDA (1998)

Mercedes Weissenbacher

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Citations (0)

Author Index, Vol. 11, 1979

Intervirology (1979)

Dominique Barbieri-Weill Serge A. Leibovitchb E Athan Rudica Emanoil-Ravicovitch J Harel

10.1159/000149061

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In vitro replication competence of a hepatitis B genotype D/A recombinant virus: dissimilar biological behaviour regarding its parental genotypes

Journal of General Virology (2013)

Julieta Trinks Masaya Sugiyama Yasuhito Tanaka Fuat Kurbanov Jorge Benetucci

Hepatitis B virus (HBV) DNA recombinants contribute to ~30% of the overall full-length sequences already deposited in GenBank. However, their biological behaviour has not been analysed so far. In this study, the in vitro replication kinetics of the first D/A recombinant from the American continent differed from its parental genotypes, exhibiting higher extracellular levels of HBV DNA and hepatitis B e antigen. Southern blots of intracellular core-associated HBV DNA were in agreement with such results. Because this recombinant was obtained from an Argentinian injecting drug user belonging to a vulnerable community, these results are of singular relevance for regional public health. Further in vivo studies are urgently needed to determine the pathogenicity of these replicative competent clones.

Orthohepadnavirus

Southern blot

10.1099/vir.0.053595-0

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Citations (1)

SEXUAL TRANSMISSION OF HEPATITIS B VIRUS, HEPATITIS C VIRUS, AND HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 INFECTIONS AMONG MALE TRANSVESTITE COMERCIAL SEX WORKERS IN MONTEVIDEO, URUGUAY

American Journal of Tropical Medicine and Hygiene (2003)

José Russi Margarita Serra José Viñoles M. T. PÉREZ Dora Ruchansky

Prostitution may constitute a risk behavior for infection with hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). We conducted a seroepidemiologic study among 200 male transvestite commercial sex workers (CSWs) in Montevideo, Uruguay in 1999. Evidence of exposure to HBV, HCV, and HIV was found in 101 (50.5%), 13 (6.5%), and 43 (21.5%) individuals, respectively. Positivity for HIV was correlated with both HBV (odds ratio [OR] = 2.15, 95% confidence interval [CI] = 1.01–4.67) and HCV (OR = 3.47, 95% CI = 0.90–12.79) infection. Predictors of infection were older age (≥ 26 years; P < 0.01) for all 3 viruses and time in CSW (≥5 years; P < 0.05) for HBV and HIV. Prior history of use of drugs (OR = 3.54, 95% CI = 1.09–11.52) and sexual contact with foreigners (OR = 9.2, 95% CI = 1.16–73.12) were found to be associated only with HCV infection. Sexual transmission of these viruses constitutes a significant problem among male transvestite CSWs.

Hepatitis virus

Sexual transmission

10.4269/ajtmh.2003.68.716

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Citations (55)

[Preliminary study on the presence of arbovirus in the populations of Corrientes and Misiones].

PubMed (1991)

Hodara Vl M Jozan H Carrera Martinez Work Th Juan Nj

Seroprevalence

Flavivirus

Parana river

Ross River virus

Alphavirus infection

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Citations (2)

Support for the RV144 HIV Vaccine Trial

Science (2004)

Robert B. Belshe Genoveffa Franchini Marc Girard Frances Gotch Pontiano Kaleebu

Currently, RV144, a phase iii clinical trial in Thailand, is evaluating the efficacy of ALVAC-HIV (vCP1521) plus gp120 (AIDSVAX B/E) as a prime-boost combination. This trial, sponsored by the U.S. and Thai governments, has been strongly criticized by D. R. Burton et al. in their Policy Forum “A

HIV vaccine

AIDS Vaccines

10.1126/science.305.5681.177b

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Citations (25)

Prevalencia de infección por el VIH-1 en enfermos de hepatitis vírica con antecedente de toxicomanía por inyección

Boletín de la Oficina sanitaria panamericana (1988)

M. Diaz Lestrem Hugo Fainboim Nápoles Méndez M Boxaca O Libonatti

L'âge moyen est de 21 ans. 90% sont du sexe masculin. On note une augmentation de la prevalence de l'agent delta dans un futur immediat

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Citations (2)