Objective TO observe the therapeutic effect of axillary osmidrosis by excision of apocrine glands under the deep dermis with a mini-incision.Methods 180 patients with axillary bromidmsis were treated by excision of apocrine glands under the deep dermis,and all these patients were followed-up for long-term results.Results The total effective rate of 180 patients who were treated by excision of apocrine gland under the deep dermis was 100% after a follow-up period ranging from 6 to 12 months.Moreover,all the patients were with well-concealed inconspicuous scales and no axillary skin necrosis.Conclusions Excision of apocrine glands under the deep dermis via a small transverse incision might be the surgical treatment of choice for axillary osmidrosis with its high effectiveness and minimal invasiveness.