Roger B. Rehr

Virginia Commonwealth University Medical Center

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Co-Authors

James L. Tatum

National Cancer Institute

Craig R. Malloy

Advanced Imaging Research (United States)

Jerry I. Hirsch

Virginia Commonwealth University

Ronald M. Peshock

The University of Texas Southwestern Medical Center

William B. Campbell

Medical College of Wisconsin

George W. Vetrovec

Virginia Commonwealth University

L. David Hillis

The University of Texas at San Antonio

Neil Filipchuk

University of Calgary

Geoffrey D. Clarke

Royal Bolton Hospital

Brian G. Firth

Johnson & Johnson (United States)

Cooperative Institutions

Virginia Commonwealth University Medical Center

Virginia Commonwealth University

The University of Texas Southwestern Medical Center

University of Texas Health Science Center at Dallas

Southwestern Medical Center

Johns Hopkins University

Hunter Holmes McGuire VA Medical Center

The University of Texas Health Science Center at Houston

University of Virginia

University of Michigan–Ann Arbor

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Detection and localization of recent myocardial infarction by magnetic resonance imaging

The American Journal of Cardiology (1986)

Neil Filipchuk Ronald M. Peshock Craig R. Malloy James R. Corbett Roger B. Rehr

10.1016/0002-9149(86)90049-4

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Citations (72)

Comparison of atrial contribution to cardiac hemodynamics in patients with normal and severely compromised cardiac function

Clinical Cardiology (1990)

Jhulan Mukharji Roger B. Rehr A Hastillo Jeremy Thompson Michael L. Hess

Abstract The importance of atrial contribution to cardiac function in patients with congestive heart failure is controversial. Ten patients with severe congestive failure (Group A) and 10 patients with normal ventricular function (Group B) were studied during atrial and ventricular pacing. Left ventricular ejection fraction, baseline pulmonary capillary wedge pressure, and baseline cardiac index were different between Group A and Group B patients: 22±10 vs. 65±11 (p<0.01); 21±5 vs. 8±4, (p<0.01); and 2.8±0.5 vs. 3.5±1.0 (p=0.05). Compared with atrial pacing, cardiac index decreased from 2.8±0.6 to 2.2±0.5 (p<O.01) in Group A and from 3.6±0.7 to 2.9±0.5 (p<0.01) in Group B, during ventricular pacing. Pulmonary capillary wedge pressure increased by similar amounts in both groups during ventricular pacing. The change in cardiac index, % change in cardiac index, and change in pulmonary capillary wedge pressure from atrial to ventricular pacing, were not different between Group A and Group B patients. By logistic regression analysis, no association was found between the % change in cardiac index and the following variables: left ventricular ejection fraction, left ventricular end‐diastolic volume, baseline pulmonary capillary wedge pressure, change in pulmonary capillary wedge pressure, and baseline cardiac index. The atrial contribution to resting steady‐state cardiac function is similar between patients with severe congestive failure and those with preserved ventricular function.

Pulmonary wedge pressure

Cardiac index

10.1002/clc.4960130910

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Citations (42)

Aortic regurgitation and sinus of Valsalva-right atrial fistula after blunt thoracic trauma.

Heart (1982)

Roger B. Rehr M Mack Brian G. Firth

Non-penetrating chest trauma commonly causes a wide variety of cardiac injuries. Disruption of the aortic valve with resultant aortic regurgitation is not uncommon; conversely, a sinus of Valsalva-right atrial fistula, in the absence of a congenital sinus of Valsalva aneurysm, has been reported only once previously. This report describes the detection by preoperative cardiac catheterisation of both aortic regurgitation, and a sinus of Valsalva-right atrial fistula after blunt chest trauma, and its surgical management. The need for preoperative cardiac catheterisation in patients suffering from non-penetrating cardiac trauma is emphasised, even when the diagnosis appears cleas, because of the diverse nature and possible multiplicity of cardiac lesions.

Sinus (botany)

Aortic sinus

10.1136/hrt.48.4.410

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Citations (12)

Reperfused-viable and reperfused-infarcted myocardium: differentiation with in vivo P-31 MR spectroscopy.

Radiology (1989)

Roger B. Rehr James L. Tatum Jerry I. Hirsch R Quint G Clarke

The ability of in vivo phosphorus-31 magnetic resonance (MR) spectroscopy to permit accurate distinction between reperfused-viable and reperfused-infarcted myocardium was examined in a canine model of acute coronary occlusion. In vivo myocardial pH and phosphocreatine, adenosine triphosphate, and inorganic phosphate levels were measured at baseline and for the first 90 minutes after reperfusion of a total coronary artery occlusion producing either predominantly viable (nine animals) or infarcted (nine animals) myocardium in the region of metabolic study. Myocardial viability was assessed in each animal by means of postmortem triphenyltetrazolium chloride staining. Tissue was characterized from the in vivo P-31 MR data by means of logistic regression analysis. The accuracy of using the P-31 MR data for distinguishing reperfused-viable from reperfused-infarcted myocardium was 100% (69 of 69 data points, 18 of 18 animals). Results of the logistic regression procedure indicated that phosphocreatine was the metabolic variable enabling most effective separation of reperfused-viable and reperfused-infarcted myocardium. Thus, metabolic data obtained with P-31 MR spectroscopy permit effective separation of reperfused-viable from reperfused-infarcted myocardium.

Coronary occlusion

10.1148/radiology.172.1.2740521

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Citations (30)

Magnetic resonance imaging in aortic valve, ascending aortic and isthmic aortic disease

The American Journal of Cardiology (1985)

Roger B. Rehr Neil Filipchuk Craig R. Malloy Ronald M. Peshock

Proton magnetic resonance

Thoracic aortic aneurysm

10.1016/0002-9149(85)90683-6

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Citations (1)

Cardiovascular nuclear magnetic resonance imaging and spectroscopy

Current Problems in Cardiology (1991)

Roger B. Rehr

10.1016/0146-2806(91)90024-5

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Citations (2)

Differentiation of reperfused-viable (stunned) from reperfused-infarcted myocardium at 1 to 3 days postreperfusion by in vivo phosphorus-31 nuclear magnetic resonance spectroscopy

American Heart Journal (1991)

Roger B. Rehr Bryan E. Fuhs Francis Lee James L. Tatum Jerry I. Hirsch

Coronary occlusion

10.1016/0002-8703(91)90273-k

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Citations (12)

Thallium-201/technetium-99m-RP-30A disparity in the course of myocardial infarction after attempted reperfusion.

PubMed (1988)

James L. Tatum Roger B. Rehr Germano DiSciascio D W Romhilt Melvin J. Fratkin

Recent reports have established that 201Tl may be taken up in areas of recent myocardial infarction after myocardial blood flow is re-established. In addition, there is accelerated 201Tl "washout" from these regions producing a pattern of "reverse redistribution." We present a case in which these phenomena may have contributed to a disparity of findings between a 201Tl stress imaging study and a repeat stress imaging study performed with a [99mTc] isonitrile (99mTc-RP-30A).

Thallium

Technetium-99m

Myocardial imaging

Source

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Citations (9)

Improved in vivo magnetic resonance imaging of acute myocardial infarction after intravenous paramagnetic contrast agent administration

The American Journal of Cardiology (1986)

Roger B. Rehr Ronald M. Peshock Craig R. Malloy Andrew Keller Robert W. Parkey

Pentetic acid

Intensity

10.1016/0002-9149(86)90628-4

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Citations (96)

Effect of Variation in Heart Size on Quantitative Thallium SPECT

Angiology (1991)

R Quint Roger B. Rehr John J. Pippin James L. Tatum

Quantitative single-photon emission tomographic (SPECT) thallium 201 (201Tl) cardiac studies are frequently used to improve test accuracy. One common technique uses polar mapping of relative tracer distribution to compare patient data to emplates from "normal" patient data. Commercial software does not correct for cardiac size variations. This study's purpose was to determine the effect of uncorrected variations in heart size on the variance of the normal population, which is the basis of template significance levels. Twenty-one male volunteers with low probability (less than 5%) for coronary disease underwent SPECT-Tl stress test. Data analysis with and without size correction was performed. Data were corrected for size by use of a three-dimensional compression/expansion algorithm. Quantitative data were generated by radial search to maximum activity in short-axis reconstructions. The mean activity and its variance was calculated from 288 points encompassing the myocardium. Mean and variance differences were analyzed by paired t test. There was no difference in activity means (pT greater than .9), indicating that size correction does not distort the data. The corrected data had, however, significantly lower variance (pT less than .0001). This shows that ventricular size variation contributes significantly to "normal" template variance and may adversely affect diagnostic accuracy in the absence of volume correction.

Thallium

Variation (astronomy)

10.1177/000331979104200907

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Citations (2)