Líbia Sanz

Research Field

The purification, crystallization and identification by X-ray diffraction analysis of a horse kallikrein is reported. The protein was purified from horse seminal plasma. Crystals belong to space group C2 and the structure was solved by the MIRAS method, with two heavy-atom derivatives of mercury and platinum. X-ray diffraction data to 1.42 Å resolution were collected at the ESRF synchrotron-radiation source.

Protein crystallization

10.1107/s0907444901009805

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Citations (3)

Respuesta a tratamiento hormonal en cáncer de próstata diseminado

Actas Urológicas Españolas (2005)

P. Serrano Frago M.J. Gil Sanz M. Allué López A. Martínez D. Pascual Regueiro

FIGURA 1. Adenopatías iliacas de aproximadamente 7 cm

10.4321/s0210-48062005000600016

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[Non-functioning retroperitoneal paraganglioma].

PubMed (1991)

O Cavero Rebollo P Urruchi Fernández A Cay Diarte M.J. Gil Sanz Carmen González Enguita

Chemodectoma

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Citations (3)

Studies on the venom proteome of Bothrops asper: Perspectives and applications

Toxicon (2009)

Alberto Alape‐Girón Marietta Flores-Dı́az Líbia Sanz Marvin Madrigal José Escolano

Proteome

Antivenom

Bothrops

10.1016/j.toxicon.2009.06.011

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Citations (52)

Proteomics and antivenomics of Papuan black snake ( Pseudechis papuanus ) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms

Journal of Proteomics (2016)

Davinia Plá Benjamin W. Bande Ronelle Welton Owen Paiva Líbia Sanz

Antivenom

Proteome

Elapidae

10.1016/j.jprot.2016.09.007

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Citations (25)

Priapism as an inicial presentation of chronic myeloid leukaemia

Actas Urológicas Españolas (2004)

M. Allué López A. Martínez D. Pascual Regueiro E. Mallén Mateo A. Villanueva Benedicto

Priapism

Chronic myeloid leukaemia

Presentation (obstetrics)

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Analysis of O-Glycosylation

Humana Press eBooks (2003)

Juan J. Calvete Líbia Sanz

AbstractSecreted as well as membrane-associated eukaryotic proteins are most commonly glycosylated. Saccharides are attached to proteins mainly through N- and O-glycosydic bonds or as part of the glycosylphosphatidyinositolmembrane anchor. In contrast to N-glycosylation, which involves the co-translational transfer in the endoplasmic reticulum (ER) of the glycan portion of Glc3Man9GlcNAc2-PP-dolichol to suitable Asn residues on nascent polypeptides, O-glycosylation begins with the addition of a single monosaccharide. Contrary to N-glycosylation, which involves an asparagine residue in the sequon Asn-Xaa-Thr/Ser (Xaa can be any amino acid except Pro, and it is rarely Cys), no particular sequence motif has been described for O-glycosylation. This may reflect the fact that: (1) the specificity of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is presently unknown; and (2) seems to be modulated by sequence context, secondary structure, and surface accessibility (1). An internet server, accessible at http://www.cbs.dtu.dk/netOglyc/cbsnetOglyc.html, produces neural network predictions of mucin-type GalNAc O-glycosylation sites in mammalian proteins based on 299 known and verified mucin-type O-glycosylation sites. The sequence context of glycosylated threonines was found to differ from that of serine, and the sites were found to cluster. Nonclustered sites had a sequence context different from that of clustered sites, and charged residues were disfavored at position −1 and +3.KeywordsNeutral SugarSequence ContextMALDI Mass SpectrometryFPLC SystemAutomate Amino Acid AnalyzerThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Sequence motif

N-linked glycosylation

10.1385/1-59259-181-7:089

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Citations (2)

Neovascularización de un tumor vesical infiltrante

Actas Urológicas Españolas (2001)

J. Oliva Encina V. Andrés Lázaro Líbia Sanz

10.1016/s0210-4806(01)72719-2

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Solution structure of jerdostatin mutant R24K from Trimeresurus jerdonii with end C-terminal residues N45G46 deleted