István Ling

Janssen (Belgium)

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Sándor Sólyom

Vichem Chemie (Hungary)

László G. Hársing

Semmelweis University

GÁ

Gizella Ábrahám

State Institute for Drug Control

Emese Csuzdi

State Institute for Drug Control

Tamás Hámori

Magyar Agrár- és Élettudományi Egyetem

József Barkóczy

Egis Pharmaceuticals (Hungary)

István Pallagi

Vichem Chemie (Hungary)

Michael Spedding

Clinical Research Solutions

Gábor Szénási

Semmelweis University

F. Antoni

University of Edinburgh

Cooperative Institutions

Egis Pharmaceuticals (Hungary)

Hungarian Academy of Sciences

Egis (France)

Semmelweis University

Eötvös Loránd University

Janssen (Belgium)

Budapest University of Technology and Economics

State Institute for Drug Control

University of Debrecen

Budapest Institute

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ChemInform Abstract: Synthesis of 1‐Azabicyclo(3.3.1)nona‐3,6‐diene Derivatives by a Modified Prins Reaction.

ChemInform (1994)

Emese Csuzdi István Ling Gizella Ábrahám I. PALLAGI Sándor Sólyom

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Diene

10.1002/chin.199435192

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Asymmetric reduction of a carbon–nitrogen double bond: enantioselective synthesis of 4,5-dihydro-3H-2,3-benzodiazepines

Journal of the Chemical Society. Perkin transactions I/Journal of the Chemical Society. Perkin transactions. I (1995)

István Ling Benjamin Podányi Tamás Hámori Sándor Sólyom

A highly specific enantioselective reduction, elaborated for the reduction of the 3,4-carbon–nitrogen double bond of 4-methyl-7,8-methylenedioxy-1-(4-nitrophenyl)-4,5-dihydro-3H-2,3-benzodiazepine 4 made possible the synthesis of the enantiomers of the potent non-competitive AMPA/kamate antagonists 2a, b. NMR Investigations of the reducing complex show that there is no formation of an 1,3,2-oxazaborolidine ring as may have been presumed on the basis of literature data.

Methylenedioxy

10.1039/p19950001423

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A novel GABAA alpha 5 receptor inhibitor with therapeutic potential

European Journal of Pharmacology (2015)

István Ling Balázs Mihalik L.-A. Etherington Gábor Kapus Adrienn Pálvölgyi

Moiety

Isoquinoline

10.1016/j.ejphar.2015.07.005

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Citations (25)

2,3-Benzodiazepine-type AMPA receptor antagonists and their neuroprotective effects

Neurochemistry International (2007)

Gábor Szénási Miklós Végh Tamás Szabó Szabolcs Kertész Gábor Kapus

Excitotoxicity

10.1016/j.neuint.2007.07.002

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Negative allosteric modulators of AMPA-preferring receptors inhibit [3H]GABA release in rat striatum

Neurochemistry International (2000)

László G. Hársing Viola Csillik‐Perczel István Ling Sándor Sólyom

Nipecotic acid

NBQX

Aminooxyacetic acid

Kainate receptor

10.1016/s0197-0186(00)00005-x

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Citations (19)

Synthesis of 1‐Azabicyclo[3.3.1]nona‐3,6‐diene Derivatives by a Modified Prins Reaction

Liebigs Annalen der Chemie (1994)

Emese Csuzdi István Ling Gizella Ábrahám István Pallagi Sándor Sólyom

Abstract Intramolecular electrophilic cyclization reactions were performed with 1‐(3‐oxo‐3‐phenylpropyl)‐1,2,5,6‐tetrahydropyridine derivatives 1a–p in strong acids to give 4,6‐diphenylsubstituted 1‐azabicyclo[3.3.1]nonadienes 2a–p . Some qualitative observations were made on substituents and reaction conditions influencing the ring closure reaction. Naphthylsubstituted starting compounds 3a, b were converted into pentacyclic compounds 4a, b which represent a new ring system, suggesting the occurrence of a carbenium ion intermediate in the ring closure reaction. Some of the compounds 2a–p show remarkable antifungal and antibacterial effects. magnified image

Diene

Closure (psychology)

Prins reaction

10.1002/jlac.199419940406

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Selective inhibition of extra-synaptic α5-GABA A receptors by S44819, a new therapeutic agent

Neuropharmacology (2017)

Lori‐An Etherington Balázs Mihalik Adrienn Pálvölgyi István Ling Katalin Pallagi

10.1016/j.neuropharm.2017.08.012

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Citations (46)