Jianfa Chen

South China University of Technology

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Xiongqi Pang

China University of Petroleum, Beijing

Zeya Chen

Tianjin University

Kaixuan Liu

Xi'an Polytechnic University

Shengbao Shi

China University of Petroleum, Beijing

Xinjian Zhu

China National Petroleum Corporation (China)

Jian Li

Research Institute of Petroleum Exploration and Development

Tieguan Wang

China University of Petroleum, Beijing

Xiaobo Wang

Henan Polytechnic University

Meijun Li

Guizhou University

Liwen He

Huaqiao University

Cooperative Institutions

China University of Petroleum, Beijing

137

Chinese Academy of Sciences

129

Research Institute of Petroleum Exploration and Development

China National Petroleum Corporation (China)

Sun Yat-sen University

Guangzhou University of Chinese Medicine

University of Chinese Academy of Sciences

Sinopec (China)

Peking University

South China University of Technology

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Hydrogen isotopic compositions of individual n-alkanes from crude oil in the central region of Junggar Basin

Goldschmidt Abstracts (2023)

Xuanyu Chen Jianfa Chen Yang Bai

Hydrogen isotope

10.7185/gold2023.16200

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[Small interfering RNA targeting Apollon enhances the chemosensitivity of hepatocellular carcinoma cells in vitro].

PubMed (2011)

Jianfa Chen Yuhua Li Yin-xiang Chen Kui-long Xie Ming Fu

To investigate the effect of small interfering RNA (siRNA) targeting Apollon in enhancing the chemosensitivity of hepatocellular carcinoma (HCC) cells in vitro.HCC cells transfected with the siRNA targeting Apollon were tested for Apollon protein expression using Western blotting. MTT assay and ELISA were used to evaluate the proliferation and apoptosis of HCC cells transfected with siRNA after exposure to 5-FU or adriamycin.Apollon siRNA obviously down-regulated Apollon protein expression in HCC cells. The siRNA-mediated suppression of Apollon expression resulted in a marked inhibition of cell growth and increased apoptotic rate of HCC cells, and enhanced both the growth-inhibiting and apoptosis-inducing effects of the chemotherapeutic drugs.Apollon siRNA can enhance the chemosensitivity of HCC cells to the chemotherapeutic drugs. Apollon can be a potentially important and feasible therapeutic target for HCC.

MTT assay

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Curing and Cross-Linking Processes in the Poly(3,3-bis-azidomethyl oxetane)-tetrahydrofuran/Toluene Diisocyanate/Trimethylolpropane System: A Density Functional Theory and Accelerated ReaxFF Molecular Dynamics Investigation

ACS Omega (2024)

Chenglong Qiu Jianfa Chen Feicheng Huan Shengwei Deng Zihao Yao

The physical and chemical properties of solid propellant are influenced by the composition and structure of the binder, with its network structure being formed through curing and cross-linking reactions. Therefore, understanding the mechanisms of these reactions is crucial. In this study, we investigated the curing and cross-linking mechanisms of poly(3,3-bis-azidomethyl oxetane)-tetrahydrofuran (PBT), toluene diisocyanate (TDI), and trimethylolpropane (TMP) using a combination of density functional theory (DFT) calculations and accelerated ReaxFF molecular dynamics (MD) simulations. DFT calculations revealed that the steric effect of the -CH

Oxetane

Trimethylolpropane

Tetrahydrofuran

Toluene diisocyanate

10.1021/acsomega.4c04558

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西湖凹陷低渗储层“甜点”预测关键技术研究与应用——以黄岩A气田为例

曹冰 Cao Bing 秦德文 Qin DeWen 陈践发

西湖凹陷目的层埋藏深，储层具有低孔渗特征，通过储层改造方能释放产能，而确定'甜点'储层发育区是储层改造成功的关键。通过岩石物理分析优选低渗储层的岩性、物性及含气性敏感参数，并设定'甜点'储层敏感参数的门槛值；利用地震正演模拟分析'甜点'储层的地震反射特征，并进行孔隙度及含气性预测的可行性分析；运用相控-叠前同步反演技术得到高精度的敏感参数体，进行目的层砂体厚度、地层切片、孔隙度、含气性及脆性指数展布特征的刻画；根据地区'甜点'储层下限值圈定各属性有利区，解释优选得到目的层储层改造'甜点'有利区；依据'甜点'预测结果设计了水平井分段压裂井的井轨迹，该井的钻探结果验证了预测结果的可靠性，水平段实现了砂岩和气层的'双百'钻遇率。

10.3969/j.issn.1000-0550.2018.020

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SOURCE ROCK AND OIL GEOCHEMISTRY AND CORRELATION IN SHUANGCHENG-TAIPINGCHUAN AREA, THE SONGLIAO BASIN

Shiyou Shiyan Dizhi (2009)

Jie Wang Wenhui Liu Tieguan Wang Jianfa Chen

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Palaeo-environmental evolution and organic matter enrichment of Eopalaeozoic shales, northwestern Tarim Basin, China: Integrated organic and inorganic geochemistry approach

Palaeogeography Palaeoclimatology Palaeoecology (2022)

Feng Li Xiuxiang Lü Jianfa Chen Rui Wang Yangyang Wang

Phytane

Isotopic signature

10.1016/j.palaeo.2022.111123

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Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid induces apoptosis and cell cycle arrest in CNE-2Z nasopharyngeal carcinoma cells

Oncology Reports (2013)

Kefeng Wu Yi Liu Yingnian Lv Liao Cui Wende Li

Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid (5F), a compound isolated from Pteris semipinnata L. (PsL), inhibits cell proliferation and induces cell apoptosis in several cancer lines. We found that 5F induced apoptosis and G2 phase cell cycle arrest in the CNE-2Z nasopharyngeal carcinoma (NPC) cells, accompanied by a decrease of NF-κB expression. 5F suppressed the viability of CNE-2Z cells in a time- and dose-dependent manner. 5F induced G2/M phase cell cycle arrest, but did not induce p21. Further analysis revealed that CNE-2Z cells harbored two p53 mutations. 5F treatment resulted in mitochondrial apoptosis, associated with increased Bax/Bcl-2 ratio, upregulation of cytochrome c in the cytosol, decreased NF-κB-p65 and increased IκB. Of note, 5F significantly sensitized CNE-2Z cells to cisplatin. 5F did not increase ROS, but reduced ROS production alone or in combination with cisplatin. Our data suggest that 5F is a potential anti-NPC drug for the development of single agent therapy and therapy in combination with cisplatin.

Viability assay

10.3892/or.2013.2375

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Freeform surface optical design of Zernike polynomials based on nodal aberration theory

sihao pan Jianfa Chen Zhifeng Pan

From the nodal aberration theory, aberration nodes will move to other locations of field of view when the optical element is decentered or tilted in rotationally symmetric system, which will lead to uncorrected off-axis aberration at locations of large field of view; cause the terms of wavefront aberration function are linked directly to the terms of Zernike polynomials, the aberrated wavefront of the system can be fitted by Zernike polynomials. At the same time, specific terms of Zernike polynomials can be selected to correct wavefront aberration efficiently by evaluating full-field display. Based on the method above, an off-axis optical system with field of view of 3°×3°is designed with two freeform surfaces and one aspheric surface, and certain Zernike polynomials are chosen as the descriptor of freeform surfaces. Keywords:Nodal aberration theory, freeform surface, Zernike polynomials, full-field display.

10.1117/12.2507971

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A STUDY ON GEOCHEMICAL CHARACTERISTICS OF CONDENSATE

Science China Chemistry (1989)

Yongchang Xu Ping Shen Jianfa Chen Wen Qi-bin

Carbon fibers

Coal measures

10.1360/yb1989-32-10-1271

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FPGA Implementation of High Throughput 2D-DCT

Journal of Xiamen University (2005)

Jianfa Chen

The discrete cosine transform(DCT) has been widely used in the implementation of low bit rate codes for video compression as an integral part of several international standards.In this paper,we present a high throughput 2D-DCT architecture with circuit designs in details,based on the algorithm of matrix row-column transposition.In order to improve the throughput performance,two technologies of pipeline structure and Double RAM Buffer are employed.At the end of this paper,the FPGA implementation and Verilog synthesis results are provided,which shows that the clock rate can achieve up to 140 MHz.It is well suited for the application in real time image and video compression system.

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